ANAL DYSPLASIA AND ANAL HPV IN HIV-POSITIVE AND HIV-NEGATIVE MEN

HIV 阳性和 HIV 阴性男性的肛门发育不良和肛门 HPV

• 批准号: 7604174
• 负责人: TIMOTHY J. WILKIN
• 金额: $ 8.61万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604174
• 关键词: Anus; Computer Retrieval of Information on Scientific Projects Database; Dysplasia; Funding; Grant; HIV; HIV Infections; Highly Active Antiretroviral Therapy; Human Papillomavirus; Immunologics; Infection; Institution; Prevalence; Race; Recording of previous events; Reporting; Research; Research Personnel; Resources; Sex Behavior; Source; Squamous intraepithelial lesion; United States National Institutes of Health; men

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aims of this study are: to define the prevalence of anal squamous intraepithelial lesions (ASIl) among HIV+ men in the era of highly active anti-retroviral therapy (HAART) as compared to HIV-negative controls; to examine the association of immunologic parameters, reported sexual behavior, race, HIV infection and HPV infection on prevalent ASIL; and to compare the prevalence and persistence of anal HPV infection between HIV+ men with a history of receptive anal intercourse, HIV+ men without this history, and HIV-negative controls.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是：与HIV阴性对照相比，在高度活跃的抗逆转录病毒疗法（HAART）的时代，在HIV+男性中定义了肛门鳞状内病变（ASIL）的患病率；检查免疫学参数的关联，报告的性行为，种族，艾滋病毒感染和HPV感染的关联；为了比较艾滋病毒+男性之间的肛门HPV感染的患病率和持久性，具有接受肛门性交的病史，没有这种病史的艾滋病毒+男性和艾滋病毒阴性控制。