MEASUREMENT OF VENTRICULAR DYSSYNCHRONY WITH CARDIAC MRI

用心脏 MRI 测量心室不同步

• 批准号: 7600822
• 负责人: SRIDHAR R CHARAGUNDLA
• 金额: $ 1.65万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7600822
• 关键词: Acceleration; Blur; Cardiac; Compatible; Computer Retrieval of Information on Scientific Projects Database; Detection; Development; Funding; Grant; Heart failure; Imaging Techniques; Institution; Magnetic Resonance Imaging; Measurement; Methods; Motion; Physiological; Radial; Research; Research Personnel; Resources; Sampling; Simulate; Source; Symptoms; United States National Institutes of Health; Ventricular; design; improved

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Ventricular dyssynchrony is an important contributing factor in the development of heart failure symptoms, however detection of this entity is suboptimal with existing imaging techniques. We seek to develop improved methods of detecting and quantifying dyssynchrony using tagged cardiac MRI. To this end, we have designed an MR-compatible motion phantom that simulates physiologic cardiac displacements, velocities, and acceleration. Preliminary results suggest that radial k-space sampling is less sensitive to motion blurring and benefits from viewsharing to a greater extent.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 心室异位障碍是心力衰竭症状发展的重要因素，但是对该实体的检测与现有成像技术相比是最佳的。 我们寻求使用标记的心脏MRI来开发改进的检测和量化失调的方法。 为此，我们设计了一个兼容MR的运动幻影，该运动模拟了生理心脏位移，速度和加速度。 初步结果表明，径向K空间采样对运动模糊和益处的敏感程度较大。