Carbon Nanotube Field Emission Micro-focus X-ray Tube

碳纳米管场发射微焦点X射线管

• 批准号: 7627961
• 负责人: Peng Wang
• 金额: $ 32.1万
• 依托单位: XINTEK, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7627961
• 关键词: Address; Animal Experimentation; Animal Sources; Animals; Anodes; Area; Binding; Biomedical Research; Carbon; Cathodes; Deposition; Development; Diagnostic radiologic examination; Dimensions; Disadvantaged; Electronics; Electrons; Film; Goals; Growth; Hour; Image; Imaging Techniques; Laboratory Animals; Length; Medical Research; Methods; Modification; Optics; Phase; Phase I Clinical Trials; Phase II Clinical Trials; Physiological; Production; Published Comment; Research Design; Resolution; Roentgen Rays; Signal Transduction; Small Animal Imaging Systems; Source; Spottings; Structure; System; Techniques; Tube; Vacuum; base; cost; design; design and construction; detector; interest; manufacturing process; meetings; particle; seal; simulation; success; tool; voltage

DESCRIPTION (provided by applicant): This is a revised Phase II application based on 2006 application and reviewers' comments. In this version, we made significant modifications, including: change the two rings cathode design to three rings structure, adding the synchronization gating control effort, and details of the processing and manufacturing of the carbon nanotube (CNT) cathodes and x-ray tubes. During this period, we achieved dramatic progress on the CNT x-ray technique, which makes us confident the success of this development. Substantial technological growth has spurred a new interest in imaging techniques, and their usage has grown considerably. High-resolution small animal imaging systems have emerged as important new tools for laboratory animal research. X-ray imaging is widely used in diagnostic radiology, biomedical research and a wide variety of industrial applications. We propose to design and construct a portable, low cost micro-focus x-ray tube using the carbon nanotube (CNT) field emission source as the cathode to overcome disadvantages of the hot electron sources in the present x-ray tubes. After Phase II, we expect to be able to develop the CNT field emision micro-focus x-ray tube with the following features: spatial resolution (effective focal spot size): adjustable with 10 5m, 30 5m, and 100 5m three levels; temporal resolution: adjustable, from 0.1 to 100 ms; X-ray tube current: adjustable, up to 2 mA peak current at 100 5m resolution; anode voltage: 40-60 KVp; synchronization gating control; and lifetime: up to 3000 hours. The primary application of the proposed x-ray source is for small animal imaging related medical research and diagonosis. The major research design and methods to achieve the proposed development goals include: 1) Construction of the micro-focus x-ray tube with resolution of 30 5m based on Phase I study; 2) Development of the compact CNT field emission 10 5m micro-focus x-ray source meeting key Phase II targets; 3) Design and assembly of the compact electronic control system for the x-ray source of Aim 2; 4) Construction of a sealed and portable micro-focus x-ray tube with the specifications of Aim 2; and 5) Demonstration of the high resolution dynamic micro-CT imaging.

描述（由申请人提供）：这是根据 2006 年申请和评审员意见修改的第二阶段申请。在此版本中，我们进行了重大修改，包括：将两环阴极设计更改为三环结构，增加了同步门控控制工作，以及碳纳米管（CNT）阴极和X射线管的加工和制造细节。在此期间，我们在碳纳米管X射线技术上取得了巨大的进展，这使我们对这项开发的成功充满信心。 技术的巨大发展激发了人们对成像技术的新兴趣，其使用量也大幅增长。高分辨率小动物成像系统已成为实验室动物研究的重要新工具。 X 射线成像广泛应用于诊断放射学、生物医学研究和各种工业应用。我们建议设计和构造一种使用碳纳米管（CNT）场发射源作为阴极的便携式、低成本微焦点X射线管，以克服现有X射线管中热电子源的缺点。二期之后，我们预计能够开发出具有以下特点的CNT场发射微焦点X射线管： 空间分辨率（有效焦斑尺寸）：有10 5m、30 5m、100 5m三个级别可调；时间分辨率：可调，从0.1到100 ms； X射线管电流：可调，100 5m分辨率下峰值电流可达2 mA；阳极电压：40-60KVp；同步门控；使用寿命：长达 3000 小时。所提出的 X 射线源的主要应用是用于小动物成像相关的医学研究和诊断。 实现拟定发展目标的主要研究设计和方法包括： 1）基于一期研究构建分辨率为30×5m的微焦点X射线管； 2）开发满足二期关键目标的紧凑型CNT场发射10 5m微焦点X射线源； 3）Aim 2 X射线源紧凑型电控系统的设计与组装； 4) 构造符合Aim 2规格的密封便携式微焦点X射线管； 5）高分辨率动态显微CT成像演示。