SEA Influenza Clinical Research Network

东南亚流感临床研究网络

• 批准号: 7664710
• 金额: $ 388.2万
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-26 至 2008-09-25
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7664710
• 关键词: SEA; Influenza; Clinical; Research; Network

NIH awarded a contract for $8 million to expand the Southeast Asian Influenza Clinical Research Network, a collaborative partnership of hospitals and institutions in Indonesia, Thailand, the United Kingdom, the United States, and Vietnam. The funding is accelerating the establishment of additional clinical research sites whose mission is to advance the scientific knowledge and management of human influenza through research into the development of therapeutics, diagnostics and vaccines. The SEA Network is currently conducting one multi-center multinational clinical trial to evaluate the efficacy of high vs. standard dose of oseltamivir for patients with severe seasonal influenza and those with avian influenza. A study has been completed on the pharmacokinetics of loading dose oseltamivir and probenecid/oseltamivir combination. Additional studies are in development.

NIH授予了800万美元的合同，以扩大东南亚流感临床研究网络，这是印度尼西亚，泰国，英国，美国和越南的医院和机构的合作伙伴关系。资金正在加速建立其他临床研究地点，其使命是通过研究治疗，诊断和疫苗的发展来推动人类流感的科学知识和管理。 SEA Network目前正在进行一项多个中心的跨国临床试验，以评估高剂量和标准剂量的Oseltamivir对严重季节性流感的患者和患有禽流感的患者的疗效。一项研究已经完成，对加载剂量oseltamivir和probenecid/oseltamivir组合的药代动力学已经完成。其他研究正在发展。