A Comprehensive Patient Based Outcome Measure for Heavy Menstral Bleeding

针对月经大量出血的基于患者的综合结果测量

基本信息

批准号：
7676689
负责人：
Kristen A Matteson
金额：
$ 16.21万
依托单位：
WOMEN AND INFANTS HOSPITAL-RHODE ISLAND
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-01 至 2013-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7676689
关键词：
Advisory Committees Affect Age Award Characteristics Clinical Medicine Clinical Research Collaborations Complex Data Data Analyses Data Collection Development Development Plans Device or Instrument Development Discipline of obstetrics Disease Educational Curriculum Electronics Ethnic Origin Etiology Evaluation Fertility Functional disorder Future Goals Gynecologic Gynecologist Gynecology Health Hemorrhage Hospitals Infant Life Measurement Measures Menstruation Disturbances Mentors Methods Outcome Outcome Measure Paper Patient Self-Report Patients Phase Population Population Heterogeneity Pregnant Women Property Psychometrics Public Health Quality of life Questionnaires Race Reporting Research Rhode Island Structure Survey Methodology Systemic disease Technology Testing Time Translating United States Universities Woman Women&apos s Health base career career development clinical care clinical practice cost design electronic data expectation experience health care service utilization innovation instrument interest member patient oriented research professor programs psychologic reproductive social

项目摘要

DESCRIPTION (provided by applicant): Dr. Kristen Matteson is Assistant Professor of Obstetrics and Gynecology at Brown University/Women and Infants Hospital of Providence, Rhode Island. The candidate's long-term goal is to develop an independent career combining clinical research with clinical medicine. The candidate is interested in the evaluation and treatment of heavy menstrual bleeding, a prevalent problem that has many causes including structural abnormalities, systemic diseases (such as bleeding disorders), and ovulatory dysfunction. Heavy menstrual bleeding has a major effect on women's health and the quality of women's lives. "Patient experience" with this condition must be evaluated and a high quality patient-based outcome measure must be developed. The proposed career development plan incorporates a multi-disciplinary program designed to provide a closely mentored patient-oriented research experience in association with a structured didactic curriculum in survey methodology and complex data analyses. In collaboration with a 7 member advisory committee, the candidate will develop a valid and reliable patient-based outcome measure ("The Menstrual Bleeding Questionnaire") for heavy menstrual bleeding. The most advanced available technology will be explored and employed for the development of the electronic format of "The Menstrual Bleeding Questionnaire". The specific aims of this study are (1)To determine the content and characteristics that gynecologists would require of an instrument for evaluation of women with heavy menstrual bleeding; (2)To explore the physical, psychological, and social factors that affect the quality of life of women with heavy menstrual bleeding; (3)To develop a menstrual bleeding-specific questionnaire that assesses amount of bleeding and "condition"-specific quality of life; (4)To develop innovative electronic methods of collecting data on patient-based outcome measures for heavy menstrual bleeding. RELEVANCE TO PUBLIC HEALTH: Heavy menstrual bleeding is a common problem that has a major impact on quality of life and health care utilization and costs. The quality of both clinical research and clinical care is adversely affected by the lack of a standardized comprehensive patient base outcome measure for women reporting heavy menstrual bleeding. This career development and research plan aims to develop a high quality patient - based outcome measure for heavy menstrual bleeding that can be used in clinical care and future research.

描述（由申请人提供）：克里斯汀·马特森（Kristen Matteson）博士是布朗大学/罗德岛州普罗维登斯妇女和婴儿医院的妇产科助理教授。候选人的长期目标是发展独立的职业，将临床研究与临床医学相结合。候选人对重度月经出血的评估和治疗感兴趣，这是一个普遍的问题，有许多原因，包括结构异常，全身性疾病（例如出血疾病）和排卵功能障碍。大量月经出血对妇女的健康和妇女生活的质量有重大影响。必须评估具有这种状况的“患者经验”，并且必须制定高质量的基于患者的结果措施。拟议的职业发展计划纳入了一项多学科计划，旨在提供密近患者的研究经验，并在调查方法和复杂的数据分析中与结构化的教学课程相关联。与7会员咨询委员会合作，候选人将针对重量出血，制定有效且可靠的基于患者的结果指标（“月经出血问卷”）。最先进的技术将被探索和使用，用于开发“月经出血问卷”的电子格式。这项研究的具体目的是（1）确定妇科医生所需的内容和特征，以评估重量大量出血的妇女；（2）探索影响月经大量出血的妇女生活质量的身体，心理和社会因素；（3）制定月经特定的问卷调查表，评估出血和“条件”特定的生活质量；（4）开发创新的电子方法，以收集有关大量月经出血的基于患者的结果指标的数据。与公共卫生相关的是：大量月经出血是一个普遍的问题，对生活质量和医疗保健利用和成本产生重大影响。临床研究和临床护理的质量都受到缺乏标准化的综合患者基础结局指标的不利影响，以报告月经出血的妇女。这项职业发展和研究计划旨在制定高质量的患者 - 基于重度月经出血的基于临床护理和未来研究的结果。