A COMPARISON OF AIRWAY CLEARANCE EFFICACY OF SINE WAVE AND TRIANGULAR WAVE HIGH

正弦波与三角波高气道清除效率比较

• 批准号: 7606073
• 负责人: Robert R KEMPAINEN
• 金额: $ 1.35万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606073
• 关键词: Agreement; Air; Chest; Computer Retrieval of Information on Scientific Projects Database; Cystic Fibrosis; Daily; Devices; Drainage procedure; Excision; Funding; Grant; High-Frequency Chest Wall Compression; Institution; Lung; Minnesota; Mucous body substance; Patients; Physiologic pulse; Pulse taking; Research; Research Personnel; Resources; Source; System; Techniques; United States; United States National Institutes of Health; Universities; cystic fibrosis patients; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Patients with cystic fibrosis (CF) must perform daily bronchial drainage therapy (BD) to keep their airways clear of secretions. Many different techniques are available to achieve this and there is currently no agreement as to which form of therapy is most effective. High frequency chest wall oscillation (HFCWO) was developed at the Minnesota CF Center and currently it is used by CF patients throughout the United States and abroad. To perform this therapy, the patient wears a vest which fits over the entire torso and is connected to an air compressor. The compressor generates oscillating air pulses that are transmitted to the lungs, thereby mobilizing secretions. The oscillations produced by the most commonly used device have a sinusoidal wave form (The Vest Airway Clearance System, Hill-Rom Inc, St. Paul, MN). Previous studies indicate this form of therapy is as effective as more tradtional cumbersome forms of therapy. The design of the pulse generator has been recently modified so that the oscillations produced have a triangular wave form (Respitech, Inc, MN). Studies done at the University of Minesota found that the air flows induced in the airways can vary substantially depending on the wave form applied to the chest. At present, the impact of using a triangular wave form on mucus removal is unknown. The proposed study will compare mucous clearance using a device generating sine wave oscillations to a device generating triangular wave oscillations.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 囊性纤维化患者（CF）必须每天进行支气管排水疗法（BD），以使其气道远离分泌。许多不同的技术可以实现这一目标，目前尚无关于哪种形式的治疗最有效的共识。高频胸壁振荡（HFCWO）是在明尼苏达州CF中心开发的，目前在美国和国外的CF患者使用它。为了进行这种疗法，患者穿着适合整个躯干的背心，并连接到空气压缩机。压缩机会产生传播到肺部的振荡空气脉冲，从而动员分泌物。最常用的设备产生的振荡具有正弦波形式（背部气道通关系统，Hill-Rom Inc，明尼苏达州圣保罗）。先前的研究表明，这种治疗形式与更繁琐的治疗形式一样有效。最近对脉冲发生器的设计进行了修改，以使产生的振荡具有三角波形（Respitech，Inc，MN）。在米内斯塔大学进行的研究发现，在气道中诱导的空气流可以根据施加到胸部的波形形式而有很大差异。目前，使用三角波形对去除粘液的去除的影响尚不清楚。拟议的研究将使用产生正弦波振荡的设备与产生三角波振荡的设备进行比较。