PEARLS Dissemination

珍珠传播

基本信息

批准号：
7680280
负责人：
Mark Snowden
金额：
$ 32.96万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-30 至 2011-09-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7680280
关键词：
PEARLS Dissemination

项目摘要

DESCRIPTION: Depression Care Management is a model of depression treatment demonstrating effectiveness in diverse settings and studies. The Program to Encourage Active and Rewarding Lives for Seniors (PEARLS) is a specific, multi-component, depression care management intervention that effectively treats minor depression and dysthymia in homebound elders. Despite its effectiveness, successful translation into everyday practice has been slow and incomplete. Use of an implementation consultant has been shown to effectively overcome organizational barriers. The purpose of this research application is to study the effects of adding consultation by an implementation management team to usual PEARLS implementation through case manager referral. The investigators hypothesize that the consultation team will facilitate greater reach of PEARLS to homebound elderly depressed patients across a county-wide region as compared to current referral-based implementation efforts. The Seattle Aging and Disabilities Services program has 50 case managers serving over 2000 homebound elderly clients, of whom 400 have depression scores consistent with dysthymia or minor depression. 25 case managers will be randomly allocated to work with PEARLS referral-based care augmented by an implementation management team and the remaining 25 will continue with usual referral-based care. One of the specific aims is to develop an implementation management team to improve PEARLS implementation. The team will include a geriatric psychiatrist, a person with PEARLS intervention expertise, and a case manager. A second aim is to develop an implementation plan for organizational assessment, staff education and training, monitoring of outcomes, and collaborative problem solving. The third aim is to conduct the trial testing the implementation methods to usual implementation and the fourth aim is to evaluate the trial. The evaluation plan will use mixed methods including both qualitative and quantitative methods to determine the reach, effectiveness, adoption, implementation fidelity, and maintenance of this implementation approach to determine the benefits of using an implementation management team.

描述：抑郁护理管理是一种抑郁症治疗的模型，表明在不同的环境和研究中有效性。鼓励老年人（珍珠）积极和奖励生活的计划是一项特定的多组分，抑郁症护理管理干预措施，可有效治疗家居长者中的轻微抑郁症和心律失常。尽管它有效，但成功地转化为日常练习还是不完整的。已显示使用实施顾问可以有效克服组织障碍。本研究申请的目的是研究通过案例经理转介将实施管理团队增加咨询到通常的珍珠实施的效果。调查人员假设，与当前基于转诊的实施工作相比，咨询团队将促进珍珠更大的珍珠覆盖范围。西雅图老龄化和残疾服务计划有50名案例经理，为2000多名家庭生活客户提供服务，其中400名抑郁症得分符合心情障碍或轻微抑郁症一致。 25个案例经理将被随机分配，以与实施管理团队的基于珍珠转介的护理增加，其余25名将继续进行通常的基于推荐的护理。具体目的之一是建立一个实施管理团队来改善珍珠实施。该团队将包括一位老年精神科医生，具有珍珠干预专业知识的人和病例经理。第二个目的是制定组织评估，员工教育和培训，对成果的监控以及协作解决问题的实施计划。第三个目的是对实施方法进行试验测试，第四个目标是评估试验。评估计划将使用包括定性和定量方法在内的混合方法来确定这种实施方法的覆盖范围，有效性，采用，实施保真度和维护，以确定使用实施管理团队的好处。

项目成果

期刊论文数量（13）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

High-sensitivity measurements of multiple kinase activities in live single cells.

DOI：
10.1016/j.cell.2014.04.039
发表时间：
2014-06-19
期刊：
Cell
影响因子：
64.5
作者：
Regot S;Hughey JJ;Bajar BT;Carrasco S;Covert MW
通讯作者：
Covert MW

Determining host metabolic limitations on viral replication via integrated modeling and experimental perturbation.

DOI：
10.1371/journal.pcbi.1002746
发表时间：
2012
期刊：
PLoS computational biology
影响因子：
4.3
作者：
Birch EW;Ruggero NA;Covert MW
通讯作者：
Covert MW

WholeCellKB: model organism databases for comprehensive whole-cell models.

DOI：
10.1093/nar/gks1108
发表时间：
2013-01
期刊：
Nucleic acids research
影响因子：
14.9
作者：
Karr JR;Sanghvi JC;Macklin DN;Arora A;Covert MW
通讯作者：
Covert MW

Accelerated discovery via a whole-cell model.

DOI：
10.1038/nmeth.2724
发表时间：
2013-12
期刊：
NATURE METHODS
影响因子：
48
作者：
Sanghvi, Jayodita C.;Regot, Sergi;Carrasco, Silvia;Karr, Jonathan R.;Gutschow, Miriam V.;Bolival, Benjamin, Jr.;Covert, Markus W.
通讯作者：
Covert, Markus W.

Why Build Whole-Cell Models?