Maintaining HIV Prevention Gains in Female Adolescents

保持女性青少年艾滋病毒预防成果

• 批准号: 7363733
• 负责人: DIANNE C MORRISON-BEEDY
• 金额: $ 61.43万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-15 至 2010-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7363733
• 关键词: AIDS prevention; Accounting; Acquired Immunodeficiency Syndrome; Address; Adolescence; Adolescent; Adult; Age; Age-Years; Behavior; Behavioral; Categories; Chlamydia; Clinic; Communities; Condition; Control Groups; Data; Disease; Elderly; Epidemic; Family Planning; Female; Female Adolescents; Frequencies; Gender; Gonorrhea; HIV; HIV Infections; Health Promotion; Healthy People 2010; Heterosexuals; Individual; Intervention; Knowledge; Maintenance; Male Adolescents; Mediating; Modeling; Motivation; Numbers; Participant; Persons; Prevalence; Prevention; Prevention intervention; Preventive; Purpose; Randomized; Randomized Controlled Trials; Rate; Recruitment Activity; Relative (related person); Reporting; Research; Risk; Risk Behaviors; Risk Reduction; Science; Sexually Transmitted Diseases; Testing; Time; Treatment Efficacy; Woman; aged; base; follow-up; health organization; male; programs; skills; transmission process

DESCRIPTION (provided by applicant): Adolescence is the only age category where the number of females becoming infected with HIV outnumber the number of males. Despite these data, only four randomized controlled trials have evaluated the efficacy of a gender-specific HIV-risk reduction program for adolescent females. The proposed research aims to address this gap in HIV prevention science, and will evaluate the short and longer-term efficacy of an HIV prevention intervention for adolescent girls. We will recruit 640 adolescent females aged 15 to 19 years from family planning clinics and randomly assign them to one of two conditions: (a) an HIV-risk reduction intervention based on the Information-Motivation-Behavioral Skills (IMB) model (Fisher & Fisher, 1992); or, (b) a structurally equivalent health promotion control group (CTL), both supplemented by booster sessions at three and six months. At a short-term (three-month) follow up, we hypothesize that IMB participants will increase HIV related knowledge, motivation, and behavioral skills, and decrease the frequency of risky sexual practices relative to CTL participants. We will reassess all participants at six and 12 months to evaluate the longer-term efficacy of the interventions. At these longer-term follow-ups, we hypothesize that IMB participants will demonstrate higher levels of HIV knowledge, motivation, and behavioral skills; decreased risky sexual practices; and decreased rates of STDs (chlamydia, gonorrhea) relative to the CTL participants. The final aim of the proposed research is to determine whether the constructs in the Information-Motivation-Behavioral Skills (IMB) Model (Fisher & Fisher, 1992), can account for variability in HIV-related behavior. We hypothesize that preventive behavior at six and 12 months will be a function of a participant's HIV-related information, motivation, and behavioral skills at the three-month follow up, and that information and motivation will be partially mediated by behavioral skills to influence the initiation and maintenance of HIV preventive behavior. The long-term intent of the proposed research is to develop a risk reduction program that can be used by community-based health organizations to reduce the risk of HIV infection among adolescent females.

描述（由申请人提供）：青春期是唯一的年龄类别，女性的数量被艾滋病毒感染了男性的数量。 尽管有这些数据，但只有四个随机对照试验评估了针对青少年女性的性别特异性艾滋病毒风险降低计划的疗效。 拟议的研究旨在解决艾滋病毒预防科学方面的这一差距，并将评估青春期女孩的艾滋病毒预防干预措施的短期和长期疗效。 我们将从计划生育诊所招募640名15至19岁的青少年女性，并将其随机分配给两个条件之一：（a）基于信息动机 - 行为行为技能（IMB）模型的HIV风险降低干预措施（Fisher＆Fisher，1992）；或（b）在结构上等效的健康促进对照组（CTL），均在三个月和六个月时补充了助推器会议。 在短期（三个月）的后续行动中，我们假设IMB参与者将增加与HIV相关的知识，动机和行为能力，并降低相对于CTL参与者的风险性行为频率。 我们将在六个月和12个月的时间重新评估所有参与者，以评估干预措施的长期疗效。 在这些长期的随访中，我们假设IMB参与者将表现出更高水平的艾滋病毒知识，动机和行为能力。危险的性行为减少；相对于CTL参与者，性病（衣原体，淋病）的发生率降低。 拟议研究的最终目的是确定信息动机行为技能（IMB）模型中的结构（Fisher＆Fisher，1992）是否可以解释与HIV相关行为的可变性。 我们假设六个月和12个月的预防行为将取决于参与者在为期三个月的随访中与参与者与HIV相关的信息，动机和行为技能的函数，并且信息和动机将由行为技能部分介导，以影响艾滋病毒预防行为的启动和维持。 拟议的研究的长期意图是制定降低风险计划，基于社区的卫生组织可以使用，以降低青少年女性中艾滋病毒感染的风险。

项目成果

Determinants of adolescent female attendance at an HIV risk reduction program.

青少年女性参加艾滋病毒风险降低计划的决定因素。

• DOI: 10.1016/j.jana.2009.11.002
• 发表时间: 2010
• 期刊: The Journal of the Association of Nurses in AIDS Care : JANAC
• 作者: Morrison-Beedy,Dianne;Carey,MichaelP;Crean,HughF;Jones,SherylH
• 通讯作者: Jones,SherylH

HIV risk behaviors and testing rates in adolescent girls: evidence to guide clinical practice.

青春期女孩的艾滋病毒风险行为和检测率：指导临床实践的证据。

• 发表时间: 2005
• 期刊: Pediatric nursing
• 作者: Morrison-Beedy,Dianne;Nelson,LaRonE;Volpe,Ellen
• 通讯作者: Volpe,Ellen

Adaptation and refinement of the HIV knowledge questionnaire for use with adolescent girls.

适应和完善艾滋病毒知识调查问卷以供青春期女孩使用。

• DOI: 10.1016/j.jana.2007.07.003
• 发表时间: 2007
• 期刊: The Journal of the Association of Nurses in AIDS Care : JANAC
• 作者: Volpe,EllenM;Nelson,LaronE;Kraus,RachelA;Morrison-Beedy,Dianne
• 通讯作者: Morrison-Beedy,Dianne

Risk reduction strategies used by urban adolescent girls in an HIV prevention trial.

城市少女在艾滋病毒预防试验中使用的降低风险策略。

• DOI: 10.2174/1570162x12666140129110129
• 发表时间: 2013
• 期刊: Current HIV research
• 影响因子: 1
• 作者: Morrison-Beedy,Dianne;Crean,HughF;Passmore,Denise;Carey,MichaelP
• 通讯作者: Carey,MichaelP

Reducing sexual risk behavior in adolescent girls: results from a randomized controlled trial.

• DOI: 10.1016/j.jadohealth.2012.07.005
• 发表时间: 2013-03
• 期刊: JOURNAL OF ADOLESCENT HEALTH
• 影响因子: 7.6
• 作者: Morrison-Beedy, Dianne;Jones, Sheryl H.;Xia, Yinglin;Tu, Xin;Crean, Hugh F.;Carey, Michael P.
• 通讯作者: Carey, Michael P.