Sustained Training in Aging and HIV Research (STAHR)

老龄化和艾滋病毒研究持续培训（STAHR）

• 批准号: 9888426
• 负责人: DILIP V. JESTE
• 金额: $ 25.07万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9888426
• 关键词: Acquired Immunodeficiency Syndrome; Address; Adult; Age; Aging; Area; Bioinformatics; Biological Markers; Biology of Aging; Biometry; California; Cessation of life; Chronic Disease; Clinical; Cognitive aging; Collaborations; Communities; Complex; Country; Development; Development Plans; Disease Management; Distance Learning; Educational workshop; Elderly; Engineering; Ethics; Evaluation; Faculty; Family Practice; Fostering; Functional disorder; Funding; Funding Mechanisms; Geriatric Psychiatry; HIV; Highly Active Antiretroviral Therapy; Home environment; Immunology; Impaired cognition; Individual; Infrastructure; Institutes; Institution; Intervention; Knowledge; Manuscripts; Medicine; Mental Health; Mental disorders; Mentors; Mentorship; Morbidity - disease rate; National Institute of Mental Health; Neuronal Plasticity; Neurosciences; Neurosciences Research; Outcome Measure; Personal Satisfaction; Pharmacy Schools; Polypharmacy; Postdoctoral Fellow; Preventive Medicine; Process; Psychiatry; Publications; Research; Research Institute; Research Personnel; Research Project Grants; Research Support; Research Training; Resources; Science; Scientist; Seeds; Sum; Training; Training Programs; Universities; career; career development; cohort; community involvement; comorbidity; cultural competence; design; experience; improved; innovation; interest; medical schools; multidisciplinary; neuroAIDS; neurobehavioral; neurocognitive disorder; neuropsychiatry; novel strategies; prevent; programs; psychosocial; public health relevance; resilience; skills; stressor; success; summer institute; summer research; translational scientist

 DESCRIPTION (provided by applicant): This application aims to develop, implement, and evaluate an innovative research training program designed to expand the number of NIMH-funded new investigators conducting mental health research at the intersection of HIV and aging. Over half of HIV-infected adults in the US are over age 50, and this number is expected to rise. The coexistence of HIV and aging in the context of mental health encompasses a complex relationship with issues of physical and psychiatric comorbidity, polypharmacy, cognitive impairment, and psychosocial stressors on one hand, and positive aspects such as successful aging, resilience, and neuroplasticity on the other. Yet, there is much to be known about pathophysiology, biomarkers, and interventions for enhancing mental health as well as for treating and preventing mental illnesses, including neurocognitive disorders, in older adults with HIV. Fostering the development of researchers with knowledge and expertise in both aging and HIV will be critical for the promotion of urgently needed research in this field. The proposed Sustained Training in Aging and HIV Research (STAHR) program builds on the infrastructure and expertise available at two major research programs at the University of California, San Diego (UCSD): the Sam and Rose Stein Institute for Research on Aging and the HIV Neurobehavioral Research Program. It seeks to address several strategic objectives of the NIMH Division of AIDS Research and the Office of AIDS Research. It will involve faculty from different departments in the UCSD School of Medicine as well as the Schools of Pharmacy and Engineering, along with mentors from other institutions. The program will target clinical and translational post- doctoral fellows and junior faculty from across the country, with previous training in either aging or HIV research, but interested in gaining expertise in the intersection o these two factors. Four new scholars will be selected every year; each will have a primary mentor at her/his home institution and a co-mentor at UCSD. These scholars will attend a 4-week summer institute during their first year and an annual 3-day workshop at UCSD for 3 years. A secondary aim of STAHR is to establish a network of mentors with interest in HIV and aging research to serve as a standing resource for the trainees. Training will aim to increase knowledge and skills on HIV/Aging research, and will also include training in research process and career development. There will be an Individual Development Plan for each scholar, which will outline mentoring activities and research experiences. Innovative distance learning opportunities will be offered in topics such as team science, funding mechanisms, mentorship training, and cultural competence. Other features include active involvement of community stakeholders, group projects, sessions on mentoring, and wide dissemination of STAHR results. There will be rigorous short and long-term evaluation of the scholars' career progress. STAHR will aim to develop high quality independently-funded investigators, who will make lasting contributions to mental health research in HIV/Aging, and sow the seeds for developing a new sub-field of Geriatric HIV Neuropsychiatry.

 描述（由申请人提供）：本申请旨在开发、实施和评估一项创新研究培训计划，旨在扩大 NIMH 资助的新研究人员的数量，在艾滋病毒和老龄化交叉领域进行心理健康研究。在美国，感染艾滋病毒的成年人年龄超过 50 岁，而且这一数字预计还会上升。在心理健康方面，艾滋病毒与老龄化的共存包含了与身体和精神共病、多重用药、认知等问题的复杂关系。一方面是损伤和心理社会压力，另一方面是成功老龄化、复原力和神经可塑性等积极方面。然而，关于病理生理学、生物标志物以及增强心理健康以及治疗和治疗的干预措施，还有很多值得了解的地方。预防感染艾滋病毒的老年人的精神疾病，包括神经认知障碍 培养具有老龄化和艾滋病毒知识和专业知识的研究人员，对于促进该领域迫切需要的研究至关重要。研究(STAHR) 项目建立在加州大学圣地亚哥分校 (UCSD) 两个主要研究项目的基础设施和专业知识的基础上：萨姆和罗斯斯坦衰老研究所和艾滋病毒神经行为研究项目。 NIMH 艾滋病研究部和艾滋病研究办公室的战略目标 该项目将涉及加州大学圣地亚哥分校医学院、药学院和工程学院不同部门的教师以及其他机构的导师。临床每年都会选出四名新学者，他们来自全国各地，接受过老龄化或艾滋病毒研究方面的培训，但有兴趣获得这两个因素的专业知识；这些学者将在第一年参加为期 4 周的暑期学院，并在 UCSD 参加为期 3 年的年度为期 3 天的研讨会。建立导师网络对艾滋病毒和老龄化研究的兴趣作为学员的长期资源。培训旨在增加艾滋病毒/老龄化研究的知识和技能，还将包括研究过程和职业发展方面的培训。每位学者将概述指导活动和研究经验，将提供创新的远程学习机会，主题包括团队科学、资助机制、指导培训和文化能力，其他特色包括社区利益相关者的积极参与、小组项目和会议。 STAHR 的指导和广泛传播STAHR 将对学者的职业进展进行严格的短期和长期评估，旨在培养高质量的独立资助的研究人员，他们将为艾滋病毒/老龄化的心理健康研究做出持久的贡献，并播下种子。开发老年艾滋病毒神经精神病学的新子领域。