Improving Outcomes for Care Partners of Persons with Traumatic Brain Injury

改善脑外伤患者护理伙伴的治疗效果

基本信息

批准号：
9886675
负责人：
Noelle E. Carlozzi
金额：
$ 66.93万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-27 至 2024-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9886675
关键词：
Accelerometer Affect Anxiety Beds Car Phone Cardiovascular Diseases Caregiver research Caregivers Caring Charge Clinical Clinical Trials Clinical Trials Design Communities Control Groups Data Data Collection Development Devices Diabetes Mellitus Emotional Stress Ensure Evaluation Face Family Family Caregiver Fatigue Feedback Financial Activity Funding Goals Health Health Priorities Heart Home environment Hour Individual Intervention Leisure Activities Life Machine Learning Measurement Measures Mental Depression Mental Health Mental disorders Monitor National Institute of Nursing Research Outcome Patient Outcomes Assessments Patient Self-Report Personal Satisfaction Persons Phenotype Physical Function Physical activity Physical assessment Population Psyche structure Quality of life Randomized Randomized Controlled Trials Rehabilitation Outcome Reporting Request for Applications Research Research Priority Risk Role Self Care Self Management Sleep Sleep disturbances Social Functioning Stress Symptoms System Time Traumatic Brain Injury Treatment Efficacy Validation Work Wrist adaptive intervention base care outcomes care recipients care systems caregiver strain caregiving control trial cost design fitbit functional outcomes group intervention health assessment health management health related quality of life high dimensionality improved improved outcome innovation insight loved ones member multidisciplinary novel physical conditioning post intervention prevent psychologic sensor sleep health smoking cessation social statistics therapy design tv watching

项目摘要

Abstract Care partners of persons with moderate to severe traumatic brain injury (TBI) are often required to assume a caregiver role, bearing primary responsibility for assisting the person with TBI in physical, mental, financial, and leisure activities. As a result of these new caregiving responsibilities, it is common for these care partners to report problems with physical, mental, and social health, as well as compromised health-related quality of life (HRQOL). Given that care partners’ well-being and functioning affects both their own personal health outcomes, as well as the functional and rehabilitation outcomes of the person with TBI, there is a critical need to develop novel health management interventions to ensure better health outcomes for both members of the TBI care partnership dyad. Therefore, our long-term goal is to improve the health and well-being of these care partners, as well as their ability to provide care to their loved one. Thus, the proposed randomized control trial will examine the efficacy of a just-in-time adaptive intervention (JITAI), or personalized self-management intervention that uses objective mobile sensor data feedback to improve physical activity, sleep, and HRQOL in 240 care partners of persons with TBI. Our primary objectives are to: 1) assess the efficacy of this novel personalized self-management intervention (i.e., JITAI) for preventing the development of adverse symptoms (e.g., mobility, sleep, poor HRQOL); and 2) use data collected from wearables (i.e., the Fitbit Charge®) and real-time assessments of HRQOL to identify care partners with the greatest risk for negative physical and mental HRQOL outcomes, as well as the timing for when they are at greatest risk. We expect care partners that are randomized to receive the JITAI will demonstrate improvements in HRQOL, physical activity and sleep relative to controls. We also hypothesize is that objective, data-derived mobile phenotypes can predict risk for adverse caregiver HRQOL. The scientific premise for the proposed research is based on our multidisciplinary team with expertise in caregiver research, evaluation of HRQOL using patient-reported outcomes, clinical trials implementation, expertise in real time assessment of HRQOL, as well as the statistical expertise in high- dimensional statistics and machine learning. Furthermore, the innovation is grounded in the examination of a real-time, real-world, personalized and scalable JITAI designed to improve HRQOL in care partners. Ultimately, this study will allow us to identify care partners at the greatest risk for negative physical and mental health outcomes, and will provide important efficacy data to support the clinical utility of a low cost, low burden self-management intervention to improve HRQOL for care partners of persons with TBI.

抽象的中度至重度创伤性脑损伤 (TBI) 患者的护理伙伴通常需要承担护理人员的角色，承担在身体、精神、经济和心理方面协助 TBI 患者的主要责任由于这些新的护理责任，这些护理伙伴通常会进行休闲活动。报告身体、心理和社会健康问题，以及与健康相关的生活质量受损 (HRQOL)。考虑到护理伙伴的福祉和功能会影响他们自己的个人健康。以及 TBI 患者的功能和康复结果，迫切需要制定新颖的健康管理干预措施，以确保双方成员获得更好的健康结果因此，我们的长期目标是改善这些护理人员的健康和福祉。伴侣，以及他们为亲人提供护理的能力，因此，提出了随机对照试验。将检查及时适应性干预（JITAI）或个性化自我管理的功效使用客观的移动传感器数据反馈来改善身体活动、睡眠和 HRQOL 的干预措施 240 名 TBI 患者的护理伙伴我们的主要目标是：1) 评估这部小说的功效。用于预防不良症状发展的个性化自我管理干预（即 JITAI）（例如，行动能力、睡眠、较差的 HRQOL）；以及 2) 使用从可穿戴设备（即 Fitbit Charge®）收集的数据；实时评估 HRQOL，以确定最有可能出现负面身体和健康状况的护理合作伙伴心理 HRQOL 结果，以及他们面临最大风险的时间。我们期望护理合作伙伴。随机接受 JITAI 的患者将在 HRQOL、体力活动和睡眠方面表现出改善相对于对照，我们还追求的是客观的、数据衍生的移动表型可以预测风险。拟议研究的科学前提基于我们的多学科。团队在护理人员研究、使用患者报告的结果评估 HRQOL、临床试验方面拥有专业知识实施、实时评估 HRQOL 的专业知识以及高水平统计专业知识此外，创新基于对维度统计和机器学习的检查。实时、真实、个性化和可扩展的 JITAI 旨在改善护理合作伙伴的 HRQOL。最终，这项研究将使我们能够确定最有可能遭受身心负面影响的护理伙伴健康结果，并将提供重要的疗效数据来支持低成本、低负担的临床效用自我管理干预，以改善 TBI 患者护理伙伴的 HRQOL。