Stanford University Regional Coordinating Stroke Center for the NIH Stroke Trials Network

斯坦福大学 NIH 卒中试验网络区域卒中协调中心

基本信息

批准号：
9755525
负责人：
GREGORY W ALBERS
金额：
$ 30.8万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9755525
关键词：
American Heart Association American Stroke Association Area Basic Science Blood Vessels Brain Injuries Caring Cerebral hemisphere hemorrhage Cerebrovascular Disorders Certification Childhood stroke Clinical Clinical Research Clinical Trials Clinical Trials Design Clinical and Translational Science Awards Collection Coma Comprehensive Health Care Country Data Set Development Diagnosis Disease Education Enrollment Faculty Fellowship Fellowship Program Funding Generations Goals Grant Hospitals Image Imaging Techniques Individual Infrastructure Intervention Joints Laboratories Laboratory Research Lead Magnetic Resonance Imaging Master of Science Medical Mentors Mission National Institute of Neurological Disorders and Stroke Neurologist Neurology Neurorehabilitation Neurosurgeon Nurses Nursing Faculty Patients Probability Procedures Protocols documentation Randomized Controlled Trials Research Research Personnel Research Project Grants Running Scientist Site Specialist Stroke Stroke prevention Techniques Testing Training Translational Research United States United States National Institutes of Health Universities X-Ray Computed Tomography acute stroke base brain tissue data management design epidemiology study experience imaging approach innovation medical schools member multidisciplinary neuroimaging neurosurgery novel strategies outcome forecast patient population programs stem cell therapy stroke recovery stroke therapy stroke trials success

项目摘要

The Stanford Stroke Center, one of the first comprehensive multidisciplinary centers of its kind, was established in 1992 to develop new approaches to diagnose and treat stroke. The mission of the Stroke Center is to be the best comprehensive organization in the United States focused on stroke diagnosis, treatment, research, and education. In 1992, the Center was established by a team of neurologists, neurosurgeons, neuroradiologists, nurse specialists, basic scientists, and clinical researchers. This multi-disciplinary team has met regularly to continually refine the program for 25 years. In 2012, the Joint Commission and the American Heart Association/American Stroke Association announced that the Stanford Stroke Center was the first hospital in the United States to meet The Joint Commission's standards for Disease-Specific Care Comprehensive Stroke Center Certification. Stanford was chosen to be one of the original StrokeNet Regional Coordinating Centers (RCCs). During the initial grant period, Stanford developed the DEFUSE 3 study, which became the first clinical trial to be funded and executed by StrokeNet. This 40-site trial has been extremely successful; enrollment rates were substantially ahead of projected targets and the trial was stopped early by the DSMB because of a high probability of efficacy in the endovascular group. Stanford's regional network is one of the highest enrollers in StrokeNet studies and Stanford faculty have made major contributions to key StrokeNet committees. The Stanford-RCC will continue to provide high volume enrollment of diverse patient populations into NINDS funded stroke trials. The Stanford RCC will also continue to offer an innovative multidisciplinary fellowship program that provides comprehensive training in clinical trial design, implementation and analysis. In addition, Stanford faculty members will continue to propose new clinical trials for implementation through StrokeNet.

斯坦福中风中心是同类中最早的综合性多学科中心之一成立于 1992 年，旨在开发诊断和治疗中风的新方法。中风中心的使命致力于成为美国最好的专注于中风诊断、治疗、研究和教育。 1992年，该中心由神经科医生、神经外科医生、神经放射科医生、护理专家、基础科学家和临床研究人员。这个多学科团队拥有 25 年来定期召开会议，不断完善该计划。 2012年，联合委员会和美国心脏协会/美国中风协会宣布斯坦福中风中心是第一个美国医院满足联合委员会的疾病特异性护理标准综合中风中心认证。斯坦福大学被选为最初的 StrokeNet 区域协调中心 (RCC) 之一。期间初始资助期间，斯坦福大学开发了 DEFUSE 3 研究，成为第一个获得资助的临床试验并由 StrokeNet 执行。这次40个站点的试验非常成功；入学率是大大提前了预期目标，并且由于高风险，DSMB 提前停止了试验血管内治疗组的疗效概率。斯坦福大学的区域网络是全球入学人数最多的网络之一 StrokeNet 研究和斯坦福大学教师为 StrokeNet 的主要委员会做出了重大贡献。这斯坦福-RCC 将继续为 NINDS 提供大量不同患者群体的注册资助中风试验。斯坦福大学 RCC 还将继续提供创新的多学科奖学金该计划提供临床试验设计、实施和分析方面的全面培训。此外，斯坦福大学的教职人员将继续提议通过 StrokeNet 实施新的临床试验。