HIV AND SUBSTANCE ABUSE LABORATORY CORE

艾滋病毒和药物滥用实验室核心

• 批准号: 7715318
• 负责人: EDDY RIOS-OLIVARES
• 金额: $ 24.26万
• 依托单位: UNIVERSIDAD CENTRAL DEL CARIBE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715318
• 关键词: AIDS/HIV problem; Area; Calculi; Collaborations; Communicable Diseases; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Development; Flow Cytometry; Fostering; Funding; Genotype; Goals; Grant; HIV; Human; Immunology; Informatics; Institution; Laboratories; Mentors; Monitor; Nucleic Acids; Pharmaceutical Preparations; Process; Productivity; Proteomics; Publications; Research; Research Personnel; Resources; Retroviridae; Sampling; Services; Source; Specimen; Substance abuse problem; Substance of Abuse; Support of Research; System; Technology; United States National Institutes of Health; addiction; chemokine; cytokine; health disparity; improved; repository; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In the last four years, the goal of this laboratory core facility has been to establish needed human and physical resources to support research studies in the area of HIV/AIDS and substances of abuse. Specialized personnel and research technology (nucleic acid extraction and amplification, genotyping, flow cytometry, proteomics, microarray, and cytokines and chemokines quantification) have become available to research studies in the areas of immunology, drugs abuse and HIV/AIDS related infectious diseases. Three external consultants (Drs. Madhavan Nair, Avindra Nath and Khan Bandiwala) and three mentors (Drs. Salin Merali, Robert Donahoe and Geoffrey Stone) are now available for guidance and effective development of the projects and in doing so, foster collaborations with local and external researchers. Support for the specimen repository as well as for the informatics system used for monitoring this repository has been provided. Improved scientific productivity (12 publications, 29 presentations in scientific meetings and more that 1,000 samples processed), and ongoing efforts to institutionalize this facility are described. In addition, service of this core facility has now been extended to include the Retrovirus Research Center, the PR Comprehensive HIV Health Disparity Center and the Center for Addiction Studies.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在过去的四年中，该实验室核心设施的目标是建立所需的人力和物理资源，以支持艾滋病毒/艾滋病领域的研究和虐待物质。 专业人员和研究技术（核酸提取和扩增，基因分型，流式细胞术，蛋白质组学，微阵列以及细胞因子和趋化因子定量）已可用于免疫学，药物滥用和HIV/AID相关感染性疾病领域的研究。 现在，现在有三名外部顾问（Madhavan Nair博士，Avindra Nath和Khan Bandiwala）和三位导师（Salin Merali博士，Robert Donahoe和Geoffrey Stone博士）可以进行指导和有效的项目开发，并在此过程中与当地和外部研究人员进行寄养。 已经提供了对标本存储库以及用于监视此存储库的信息系统的支持。 提高了科学生产力（12个出版物，29个科学会议中的演讲，还有1,000个样本处理），并介绍了使该设施制度化的持续努力。 此外，现在已经扩展了此核心设施的服务，包括逆转录病毒研究中心，PR综合HIV健康差异中心和成瘾研究中心。