Mentoring alcohol use intervention research in HIV health care settings

指导艾滋病毒卫生保健机构中的酒精使用干预研究

• 批准号: 10762918
• 负责人: Derek D Satre
• 金额: $ 19.65万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-20 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10762918
• 关键词: Acquired Immunodeficiency Syndrome; Address; Affect; Alcohol consumption; Alcohols; Area; Award; Behavioral Sciences; Black Populations; California; Cardiovascular Diseases; Cardiovascular system; Caring; Characteristics; Clinical; Continuity of Patient Care; Data; Data Set; Development; Diagnosis; Discrimination; Disparity; Electronic Health Record; Epidemic; Ethnic Origin; Event; Faculty; Female; Funding; Goals; Grant; Grouping; HIV; HIV risk; HIV/AIDS; Health; Health system; Healthcare; Individual; Infrastructure; Interdisciplinary Study; Intervention; Intervention Studies; Interview; K-Series Research Career Programs; Latinx population; Medical; Medicine; Mental Depression; Mental Health; Mental disorders; Mentors; Obesity; Outcome; Paper; Parents; Patients; Pattern; Persons; Play; Population; Population Heterogeneity; Positioning Attribute; Prevention; Probability; Productivity; Psychiatry; Psychosocial Factor; Publishing; Registries; Reporting; Research; Research Personnel; Resources; Risk; Risk Behaviors; Risk Factors; Role; Sampling; San Francisco; Scientist; Services; Sex Differences; Sexually Transmitted Diseases; Subgroup; Training; Training Programs; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Universities; Viral; Visit; Woman; Work; alcohol abuse therapy; alcohol availability; alcohol intervention; alcohol misuse; alcohol related problem; alcohol research; alcohol risk; alcohol screening; antiretroviral therapy; cardiometabolic risk; cardiovascular risk factor; care outcomes; career; cigarette smoking; comorbidity; drinking; effective intervention; ethnic difference; ethnic disparity; ethnic minority; ethnic minority population; experience; health care settings; health disparity; high risk population; implementation intervention; implementation science; improved; infection rate; innovation; medical specialties; men; mortality; multiple chronic conditions; novel strategies; patient oriented research; person centered; physical conditioning; professor; programs; psychiatric comorbidity; racial difference; racial disparity; racial diversity; racial minority; racial minority population; screening; social health determinants; social stigma; substance use; syndemic; therapy development; transmission process

Project Summary/Abstract Unhealthy alcohol use plays a major role in risk for and exacerbation of HIV/AIDS. There is an urgent need to implement effective alcohol intervention strategies, train new researchers, and reduce ongoing health disparities in order to end the HIV epidemic. Addressing these critical issues, this K24 renewal application proposes to extend the mentoring program in patient-oriented research (POR) of Dr. Derek Satre, Professor in the University of California, San Francisco (UCSF), Department of Psychiatry and Behavioral Sciences, and Adjunct Investigator in the Kaiser Permanente Northern California Division of Research (DOR). Dr. Satre’s research program is focused on alcohol interventions in the context of HIV care, including serious comorbidities such other substance use, mental health problems, and medical conditions. In the current K24 cycle, Dr. Satre has met and exceeded the aims of the award and been highly productive: he has published 75 papers (36 with mentees as first author) and obtained two R01s in HIV and alcohol research based in health systems. His mentees are primarily clinicians and they have been very successful in their research careers, including two K awards with Dr. Satre as primary mentor, and many other mentees have received NIH grants and faculty positions. This renewal will enhance Dr. Satre’s ability to develop, and implement effective alcohol interventions with people with HIV (PWH) especially racial/ethnic minorities, who are disproportionately impacted. His mentoring will continue to be based in alcohol and HIV health settings and outstanding training programs. New in this renewal, he proposes to develop an innovative alcohol POR mentoring program within the UCSF Center for AIDS Prevention Studies (CAPS) Visiting Professor Program, to enhance the careers of underrepresented minority junior scientists. Mentees will leverage the infrastructure and resources of Dr. Satre’s ongoing studies, which include large alcohol and HIV data sets and multidisciplinary research collaborators. Dr. Satre proposes to further enhance his clinical POR mentoring by obtaining training in implementation science and social determinants of health. The proposed research to be conducted with mentees extends his recently funded R01 to examine alcohol risk profiles, access to alcohol treatment and HIV clinical outcomes, to inform alcohol intervention implementation. In summary, this K24 renewal will leverage Dr. Satre’s research mentoring program with extensive infrastructure at UCSF and DOR to support a program of expanded POR mentoring in alcohol and HIV intervention research, to advance the goal of implementing effective interventions to reduce alcohol-related problems for PWH.

项目摘要/摘要 不健康的饮酒在艾滋病毒/艾滋病的风险和加剧中起着重要作用。迫切需要 实施有效的酒精干预策略，培训新研究人员并降低持续的健康状况 差异是为了结束艾滋病毒的流行。解决这些关键问题，此K24更新应用程序 提议扩大以患者为导向的研究（POR）Derek Satre博士的心理计划的提议 加州大学旧金山大学（UCSF），精神病学和行为科学系， Kaiser Permanente北加州研究部（DOR）的兼职研究员。 Satre博士 研究计划的重点是在艾滋病毒护理的背景下进行酒精干预，包括严重 合并症，例如其他药物使用，心理健康问题和医疗状况。在当前的K24中 骑自行车，萨特雷博士已经达到并超出了该奖项的目标，并且高度生产力：他已经出版了75 论文（36名与梅内斯（Menees）作为第一作者），并获得了基于卫生的HIV和酒精研究的两个R01 系统。他的Menees是主要临床医生，他们在研究职业中非常成功， 包括SATRE博士作为主要导师，包括两个K奖，许多其他MENET都获得了NIH赠款 和教师职位。这种更新将增强萨特雷博士的发展和实施有效酒精的能力 与艾滋病毒（PWH）尤其是种族/族裔少数群体的干预措施，他们不成比例 受影响。他的心理将继续以酒精和艾滋病毒健康环境和出色的培训为基础 程序。在此续约中，他提议在此内制定创新的酒精心理计划 UCSF艾滋病预防研究中心（CAPS）访问教授计划，以增强 代表性不足的少数民族初级科学家。受训者将利用博士的基础设施和资源。 Satre的正在进行的研究包括大型酒精和艾滋病毒数据集和多学科研究 合作者。 Satre博士提出的建议，以进一步增强他的临床心理性。 实施科学和卫生的社会决定者。提出的研究与 门德斯扩展了他最近资助的R01，以检查酒精风险概况，获得酒精治疗和艾滋病毒 临床结果，以告知酒精干预的实施。总而言之，此K24更新将利用 Satre博士的研究心理计划，在UCSF和DOR上具有广泛的基础设施，以支持该计划 在酒精和艾滋病毒干预研究中进行的越来越多的POR精神 有效的干预措施以减少PWH的酒精相关问题。

项目成果

Patient and provider factors associated with receipt and delivery of brief interventions for unhealthy alcohol use in primary care.

• DOI: 10.1111/acer.14702
• 发表时间: 2021-10
• 期刊: Alcoholism, clinical and experimental research
• 作者: Lu Y;Chi FW;Parthasarathy S;Palzes VA;Kline-Simon AH;Metz VE;Weisner C;Satre DD;Campbell CI;Elson J;Ross TB;Awsare SV;Sterling SA
• 通讯作者: Sterling SA

Remission From Unhealthy Drinking Among Patients With an Alcohol Use Disorder: A Longitudinal Study Using Systematic, Primary Care-Based Alcohol Screening Data.

酒精使用障碍患者不健康饮酒的缓解：一项使用系统的、基于初级保健的酒精筛查数据的纵向研究。

• DOI: 10.15288/jsad.2020.81.436
• 发表时间: 2020
• 期刊: Journal of studies on alcohol and drugs
• 影响因子: 3.4
• 作者: Palzes,VanessaA;Kline-Simon,AndreaH;Satre,DerekD;Sterling,Stacy;Weisner,Constance;Chi,FeliciaW
• 通讯作者: Chi,FeliciaW

Risk profiles of adults with heavy alcohol use: Drinking patterns, behavioral and metabolic factors, health problems, and racial and ethnic disparities.

成人大量饮酒的风险概况：饮酒模式、行为和代谢因素、健康问题以及种族和民族差异。

• DOI: 10.1111/acer.15211
• 发表时间: 2023
• 期刊: Alcohol, clinical & experimental research
• 作者: Palzes,VanessaA;Chi,FeliciaW;Weisner,Constance;Kline-Simon,AndreaH;Satre,DerekD;Sterling,Stacy
• 通讯作者: Sterling,Stacy