Virtual Reality Technologies for Dynamic Balance Rehabilitation in People with Stroke

用于中风患者动态平衡康复的虚拟现实技术

• 批准号: 10760428
• 负责人: BRIAN D SCHMIT
• 金额: $ 27.43万
• 依托单位: KOBUK TECHNOLOGIES LLC
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-14 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10760428
• 关键词: Advanced Development; Affect; Balance training; Clinic; Clinical; Clinical Research; Computer software; Coupling; Data; Development; Effectiveness; Elements; Environment; Equilibrium; Equipment; Exertion; Fatigue; Feasibility Studies; Future; Gait; Guidelines; Hand; Heart Rate; Individual; Knowledge; Laboratories; Length; Life; Location; Measures; Motion Sickness; Movement; Neurologic; Participant; Patients; Persons; Phase; Physical therapy; Population; Process; Protocols documentation; Quality of life; Questionnaires; Rehabilitation therapy; Research; Rest; Risk Reduction; Small Business Technology Transfer Research; Speed; Stroke; Surveys; System; Systems Development; Technology; Testing; Therapeutic Intervention; Thinness; Time; Training; Translations; Universities; Visual; Visual Fields; Walking; Work; balance recovery; clinical practice; cost; dynamic system; efficacy clinical trial; efficacy testing; efficacy trial; fall risk; falls; feasibility testing; gait rehabilitation; improved; innovation; kinematics; nervous system disorder; novel; prototype; response; side effect; software development; stroke patient; tool; treadmill; treadmill training; virtual; virtual reality; virtual reality environment; virtual reality headset; virtual reality system; walking speed; wireless

PROJECT SUMMARY/ABSTRACT This project aims to quantify and establish elements of immersive virtual reality (VR) software that, when paired with treadmill training, produce balance perturbations that can be scaled to improve dynamic balance and are tolerated by people with stroke. VR continues to be used as an interactive and engaging way for clinicians to interact with patients during physical therapy, increasing effort given by patients and reducing costs of equipment. There lacks, however, a proven immersive VR system that works for dynamic balance rehabilitation protocols for neurological patients, such as those with stroke, to improve balance during walking. Improvements in dynamic balance would lead to a decreased risk of falls, increased mobility, and would ultimately improve quality of life for patients. In addition, a VR system that can be used on a treadmill to train balance would fill an unmet clinical need for task-specific therapeutic interventions to reduce the risk of falls in people with stroke. Kobuk Technologies has developed an alpha version of such a system and will work together with Dr. Schmit at Marquette University to advance development of the system so that it can be tested in people with stroke. A feasibility study will then be conducted in people with stroke to ascertain how the system challenges balance by encouraging users to reach for targets in the VR environment while stepping on a treadmill. Information from this study will then be used to build a beta version of the VR system for efficacy testing. Aim I of the proposed research in this STTR Phase I will focus on quantifying balance responses to reaching in an immersive VR environment on a treadmill, as these data are required scaling difficulty of the VR reaching tasks. Aim II will characterize the coupling of treadmill speed and reach in a VR environment since individual walking speeds for such a system will be necessary. Aim III will determine the length of time that people with stroke tolerate an immersive VR environment during treadmill stepping. This research is critical to the development of a VR treadmill training system for the rehabilitation of balance. The project will yield a VR system that can then be used in an STTR Phase II efficacy trial to demonstrate improvements in gait function in neurologic patients. Ultimately, Kobuk Technologies will create a new low cost tool for clinicians to use with their patients during treadmill training that will substantially enhance the effectiveness of gait rehabilitation.

项目摘要/摘要 该项目旨在量化和建立沉浸式虚拟现实（VR）软件的要素， 与跑步机训练配对，产生可以缩放的平衡扰动，以提高动态平衡 并被中风的人容忍。 VR继续用作互动和引人入胜的方式 临床医生在物理治疗期间与患者互动，患者给予的努力增加并减少 设备成本。然而，缺乏一个可实现动态平衡的经过验证的沉浸式VR系统 神经系统患者（例如中风患者）的康复方案，以改善步行过程中的平衡。 动态平衡的改善将导致跌倒风险降低，流动性增加，并且会导致 最终改善了患者的生活质量。此外，可以在跑步机上使用的VR系统训练 余额将满足未满足的特定任务治疗干预措施的临床需求，以降低跌倒的风险 患有中风的人。 Kobuk Technologies开发了这样的系统的Alpha版本，并将起作用 与Marquette University的Schmit博士一起推进系统的开发，以便可以对其进行测试 在中风的人。然后，将对中风的人进行可行性研究，以确定 系统通过鼓励用户在VR环境中达到目标来挑战平衡 跑步机。然后，本研究的信息将用于构建VR系统的Beta版本以供疗效 测试。在此sttr阶段，拟议研究的目的我将重点介绍量化平衡响应 在跑步机上的沉浸式VR环境中到达，因为这些数据需要缩放VR的难度 达到任务。 AIM II将表征跑步机速度并在VR环境中触及到的耦合 需要为这样一个系统的单个步行速度。 AIM III将确定 跑步机步进期间，中风的人可以容忍沉浸式VR环境。这项研究对 VR跑步机训练系统的开发，用于恢复平衡。该项目将产生VR 然后可以在STTR II期有效性试验中使用以证明步态功能的改进的系统 在神经系统患者中。最终，Kobuk Technologies将为临床医生创建一个新的低成本工具 他们在跑步机训练中的患者将大大提高步态康复的有效性。