Virtual Reality Technologies for Dynamic Balance Rehabilitation in People with Stroke

用于中风患者动态平衡康复的虚拟现实技术

• 批准号: 10760428
• 负责人: BRIAN D SCHMIT
• 金额: $ 27.43万
• 依托单位: KOBUK TECHNOLOGIES LLC
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-14 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10760428
• 关键词: Advanced Development; Affect; Balance training; Clinic; Clinical; Clinical Research; Computer software; Coupling; Data; Development; Effectiveness; Elements; Environment; Equilibrium; Equipment; Exertion; Fatigue; Feasibility Studies; Future; Gait; Guidelines; Hand; Heart Rate; Individual; Knowledge; Laboratories; Length; Life; Location; Measures; Motion Sickness; Movement; Neurologic; Participant; Patients; Persons; Phase; Physical therapy; Population; Process; Protocols documentation; Quality of life; Questionnaires; Rehabilitation therapy; Research; Rest; Risk Reduction; Small Business Technology Transfer Research; Speed; Stroke; Surveys; System; Systems Development; Technology; Testing; Therapeutic Intervention; Thinness; Time; Training; Translations; Universities; Visual; Visual Fields; Walking; Work; balance recovery; clinical practice; cost; dynamic system; efficacy clinical trial; efficacy testing; efficacy trial; fall risk; falls; feasibility testing; gait rehabilitation; improved; innovation; kinematics; nervous system disorder; novel; prototype; response; side effect; software development; stroke patient; tool; treadmill; treadmill training; virtual; virtual reality; virtual reality environment; virtual reality headset; virtual reality system; walking speed; wireless

PROJECT SUMMARY/ABSTRACT This project aims to quantify and establish elements of immersive virtual reality (VR) software that, when paired with treadmill training, produce balance perturbations that can be scaled to improve dynamic balance and are tolerated by people with stroke. VR continues to be used as an interactive and engaging way for clinicians to interact with patients during physical therapy, increasing effort given by patients and reducing costs of equipment. There lacks, however, a proven immersive VR system that works for dynamic balance rehabilitation protocols for neurological patients, such as those with stroke, to improve balance during walking. Improvements in dynamic balance would lead to a decreased risk of falls, increased mobility, and would ultimately improve quality of life for patients. In addition, a VR system that can be used on a treadmill to train balance would fill an unmet clinical need for task-specific therapeutic interventions to reduce the risk of falls in people with stroke. Kobuk Technologies has developed an alpha version of such a system and will work together with Dr. Schmit at Marquette University to advance development of the system so that it can be tested in people with stroke. A feasibility study will then be conducted in people with stroke to ascertain how the system challenges balance by encouraging users to reach for targets in the VR environment while stepping on a treadmill. Information from this study will then be used to build a beta version of the VR system for efficacy testing. Aim I of the proposed research in this STTR Phase I will focus on quantifying balance responses to reaching in an immersive VR environment on a treadmill, as these data are required scaling difficulty of the VR reaching tasks. Aim II will characterize the coupling of treadmill speed and reach in a VR environment since individual walking speeds for such a system will be necessary. Aim III will determine the length of time that people with stroke tolerate an immersive VR environment during treadmill stepping. This research is critical to the development of a VR treadmill training system for the rehabilitation of balance. The project will yield a VR system that can then be used in an STTR Phase II efficacy trial to demonstrate improvements in gait function in neurologic patients. Ultimately, Kobuk Technologies will create a new low cost tool for clinicians to use with their patients during treadmill training that will substantially enhance the effectiveness of gait rehabilitation.

项目概要/摘要 该项目旨在量化和建立沉浸式虚拟现实（VR）软件的元素，当 与跑步机训练相结合，产生可调节的平衡扰动以改善动态平衡 并且中风患者可以耐受。 VR 继续被用作一种互动且引人入胜的方式 临床医生在物理治疗期间与患者互动，增加患者的努力并减少 设备成本。然而，缺乏经过验证的可实现动态平衡的沉浸式 VR 系统 针对神经系统患者（例如中风患者）的康复方案，以改善行走时的平衡能力。 动态平衡的改善会降低跌倒的风险，增加活动能力，并会 最终提高患者的生活质量。此外，还有一个VR系统，可以在跑步机上使用来训练 平衡将满足针对特定任务的治疗干预措施的未满足的临床需求，以降低跌倒的风险 中风患者。 Kobuk Technologies 已开发出此类系统的 alpha 版本，并且可以运行 与马凯特大学的施密特博士一起推进系统的开发，以便进行测试 中风患者。然后将对中风患者进行可行性研究，以确定如何 系统通过鼓励用户在 VR 环境中踩踏时达到目标来挑战平衡 跑步机。这项研究的信息将用于构建 VR 系统的测试版以提高功效 测试。 STTR 第一阶段拟议研究的目标 I 将侧重于量化平衡反应 在跑步机上达到沉浸式 VR 环境，因为这些数据需要缩放 VR 的难度 达成任务。 Aim II 将在 VR 环境中表征跑步机速度和范围的耦合 这种系统需要单独的行走速度。目标 III 将决定该时间的长度 中风患者在跑步机上行走时可以忍受沉浸式 VR 环境。这项研究对于 开发用于平衡康复的VR跑步机训练系统。该项目将产生 VR 然后可用于 STTR II 期疗效试验以证明步态功能的改善 在神经系统患者中。最终，Kobuk Technologies 将创建一种新的低成本工具，供临床医生使用 他们的患者在跑步机上进行训练，这将大大提高步态康复的有效性。