Mentoring in Translational Research to Prevent Disparities in Childhood Obesity and Cardiometabolic Disease

指导转化研究以防止儿童肥胖和心血管代谢疾病的差异

基本信息

批准号：
10722684
负责人：
Anisha Indravadan Patel
金额：
$ 12.48万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-08 至 2028-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10722684
关键词：
Acculturation Adoption Affect Age Award Biometry Cardiometabolic Disease Child Child Care Clinical Clinical Investigator Cluster randomized trial Collaborations Communities Computer software Cost Effectiveness Analysis Data Development Dietary Assessment Disease Disparity Dissemination and Implementation Education Effectiveness Environment Ethnic Origin Faculty Feedback Fellowship Fostering Foundations Funding Future Grant Health Health Policy Health Services Research Home Income Institution Intake Intervention Leadership Learning Los Angeles Low income Maintenance Manuscripts Maternal and Child Health Mentors Mentorship Methods Mid-Career Clinical Scientist Award (K24)Midcareer Investigator Award in Patient-Oriented Research Minority Groups National Heart, Lung, and Blood Institute Nutrition Policy Obesity Overweight Pediatrics Policies Policy Maker Population Prevention strategy Public Health Publishing Race Randomized, Controlled Trials Reach, Effectiveness, Adoption, Implementation, and Maintenance Recording of previous events Research Research Institute Research Personnel Research Training Residencies Resources Role San Francisco Schools Science Scientist Statistical Data Interpretation Students Subgroup Time Training Training Programs Training and Infrastructure Translating Translational Research Translations Vision Vocational Guidance Water Water consumption Work cardiometabolism career career development children of color clinical center community engaged research community setting cost dissemination science drinking water economic evaluation elementary school ethnic disparity evidence base experience health organization implementation intervention implementation research implementation science implementation strategy improved innovation medical schools mid-career faculty multidisciplinary novel obesity in children obesity prevention patient oriented research pediatric department pediatrician peer coaching population health prevent programs racial disparity sex skills socioeconomic disparity sugar sweetened beverage therapy development training opportunity undergraduate student

Acculturation Adoption Affect Age Award Biometry Cardiometabolic Disease Child Child Care Clinical Clinical Investigator Cluster randomized trial Collaborations Communities Computer software Cost Effectiveness Analysis Data Development Dietary Assessment Disease Disparity Dissemination and Implementation Education Effectiveness Environment Ethnic Origin Faculty Feedback Fellowship Fostering Foundations Funding Future Grant Health Health Policy Health Services Research Home Income Institution Intake Intervention Leadership Learning Los Angeles Low income Maintenance Manuscripts Maternal and Child Health Mentors Mentorship Methods Mid-Career Clinical Scientist Award (K24)Midcareer Investigator Award in Patient-Oriented Research Minority Groups National Heart, Lung, and Blood Institute Nutrition Policy Obesity Overweight Pediatrics Policies Policy Maker Population Prevention strategy Public Health Publishing Race Randomized, Controlled Trials Reach, Effectiveness, Adoption, Implementation, and Maintenance Recording of previous events Research Research Institute Research Personnel Research Training Residencies Resources Role San Francisco Schools Science Scientist Statistical Data Interpretation Students Subgroup Time Training Training Programs Training and Infrastructure Translating Translational Research Translations Vision Vocational Guidance Water Water consumption Work cardiometabolism career career development children of color clinical center community engaged research community setting cost dissemination science drinking water economic evaluation elementary school ethnic disparity evidence base experience health organization implementation intervention implementation research implementation science implementation strategy improved innovation medical schools mid-career faculty multidisciplinary novel obesity in children obesity prevention patient oriented research pediatric department pediatrician peer coaching population health prevent programs racial disparity sex skills socioeconomic disparity sugar sweetened beverage therapy development training opportunity undergraduate student

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项目摘要

PROJECT SUMMARY/ABSTRACT Dr. Anisha Patel is a midcareer pediatrician-researcher at Stanford applying for a K24 Midcareer Investigator Award in Patient-Oriented Research (POR). Dr. Patel has excellent training in research (public health, health services research, community-engaged research, health policy). She has built an innovative research program that leverages community-academic-policy partnerships to prevent racial/ethnic and income-related disparities in obesity and cardiometabolic diseases funded by federal agencies, foundations, and institutional support. She also has an extensive history of mentoring in POR, with a particular emphasis on trainees underrepresented in health fields. As Associate Professor of Pediatrics at Stanford in many formal mentoring roles and as Director of Community-Engaged Research in Stanford’s Maternal and Child Health Research Institute, Dr. Patel is poised to mentor early and junior clinician-investigators in translational science. Dr. Patel is conducting numerous community-engaged studies to prevent racial/ethnic and socioeconomic disparities in childhood obesity that provide training opportunities for mentees. The first two aims of this application focus on two R01-funded cluster randomized-controlled trials (CRTs) examining the impact of drinking water promotion and access on children’s intake of water and sugar-sweetened beverages, and obesity in elementary schools (Water First, n=1249 students) and childcare centers (Healthy Drinks, Healthy Futures, n=420 children).This K24 award will leverage these two trials by applying the RE-AIM framework to examine the interventions’ reach, effectiveness, adoption, implementation, cost, and maintenance. The Specific Aims are to: 1) Estimate the short-term cost, population reach and effectiveness of Water First and Heathy Drinks, Healthy Futures interventions in increasing water intake, decreasing SSB intake, and preventing overweight, 2) Examine the impact of the interventions among different subgroups (by age, sex, racial/ethnic background, English proficiency and acculturation level), and 3) Describe how the impact of the interventions differ by fidelity to the intervention implementation strategies. These data will be used to translate evidence into practice and adapt the interventions for “real-world” settings. The research will also provide a platform for training experiences in conduct of CRTs, community-engaged research, dissemination and implementation science, intervention development, mixed methods, dietary assessment, and statistical analysis. The award will also allow Dr. Patel to expand her mentoring of early stage clinical investigators pursing translational POR and support her own career development in 1) gaining and applying mentorship and leadership skills, 2) building novel research with multi-disciplinary investigators, and 3) fostering new research expertise in dissemination and implementation research and economic evaluation at an opportune time in her career.

项目摘要/摘要阿尼莎·帕特尔（Anisha Patel）博士是斯坦福大学的中级儿科研究员以患者为导向的研究奖（POR）。帕特尔博士在研究方面拥有出色的培训（公共卫生，健康服务研究，社区参与研究，卫生政策）。她已经建立了一个创新的研究计划利用社区学术 - 政策伙伴关系来防止种族/种族和收入相关的差距由联邦机构，基金会和机构支持资助的肥胖和心脏代谢疾病。她在POR中也有广泛的心理历史，特别着重于学员在健康领域的人数不足。作为许多正式心理的斯坦福大学儿科副教授角色和斯坦福儿童健康研究中社区参与研究主任研究所，帕特尔博士被转化科学的早期和初级临床评估者中毒。帕特尔博士正在进行大量社区参与研究，以防止种族/种族和社会经济差异为门德提供培训机会的童年对象。该应用程序的前两个目的重点是两个R01资助的群集随机控制试验（CRT）检查了饮用水促进的影响以及儿童摄入水和糖效的卧室以及小学的肥胖（第一水，n = 1249名学生）和育儿中心（健康饮料，健康期货，n = 420个孩子）。 K24奖将通过应用RE-AIM框架来检查干预措施来利用这两个试验。覆盖，有效性，采用，实施，成本和维护。具体目的是：1）估计首先，水和热饮料的短期成本，人口覆盖率和有效性，健康的未来干预摄入量增加，减少SSB摄入量并防止超重的干预措施，2）检查不同子组之间干预措施的影响（按年龄，性别，种族/种族背景，英语熟练程度和文化化水平），以及3）描述干预措施的影响如何因忠诚对干预实施策略。这些数据将用于将证据转化为实践并适应 “现实世界”设置的干预措施。该研究还将为培训经验提供一个平台 CRT的进行，社区参与研究，传播和实施科学，干预开发，混合方法，饮食评估和统计分析。该奖项还将允许帕特尔博士扩大她对早期临床调查人员追求翻译的心理，并支持自己的 1）获得和运用指导和领导能力的职业发展，2）与多学科研究人员，以及3）培养传播和实施方面的新研究专业知识在她职业生涯的机会时期的研究和经济评估。