Biological Underpinnings of Maternal Attachment in High Risk Populations

高危人群母性依恋的生物学基础

基本信息

批准号：
9292069
负责人：
JEANNE L ALHUSEN
金额：
$ 14.66万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-02 至 2019-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9292069
关键词：
Address Adult Affect Age Area Attenuated Award Behavior Berlin Biological Biological Process Biology Caucasians Child Child Development Child Rearing Childhood Chronic stress Collection Complex Data Analyses Development Doctor of Philosophy Early Intervention Effectiveness Emotional Family Foundations Generations Goals Health Home visitation Hormones Human Hydrocortisone Impairment Income Individual Infant Intervention Knowledge Life Low income Measures Mental Health Mentors Mentorship Mother-Child Relations Mothers Neonatal Neuropeptides Outcome Outcomes Research Oxytocin Parent-Child Relations Physiological Physiological Processes Physiology Poverty Process Regulation Research Research Training Role Sampling Secure Security Shapes Site Statistical Data Interpretation Stress Supervision Training Treatment outcome Universities Virginia Woman Work biobehavior career caregiving cognitive development community setting design early childhood effective intervention ethnic minority population high risk population hypothalamic pituitary axis improved intervention program multidisciplinary primary caregiver programs protective behavior psychologic psychosocial public health relevance racial diversity response responsible research conduct skills social therapy design urban poverty

项目摘要

DESCRIPTION (provided by applicant): This K23 application prepares the candidate, Jeanne Alhusen, PhD, for a research-intensive career leading multidisciplinary efforts to improve early childhood outcomes in children targeted by early intervention programs in community settings. Specifically, I aim to become an expert in the biological and psychological underpinnings of maternal attachment and its influence on maternal-child physiological attunement, and ultimately early childhood outcomes. Understanding these relations is critical in understanding, from a biological perspective, how secure maternal attachment may confer developmental advantages in young children living in poverty and how maternal biology can impact the effectiveness of early interventions. The overall aims of this proposal are to (a) examine the relations among maternal cortisol, oxytocin, attachment style, sensitivity, (b) examine the moderating role of maternal-child cortisol attunement on the association between maternal attachment style and maternal sensitivity and (c) examine the associations between maternal-child cortisol attunement and early childhood outcomes in 75 mother-child dyads living in urban poverty. In the short-term, the current proposal will allow me to gain the skills and expertise to conduct mentored research on the biological and psychological underpinnings of maternal attachment and their relation to maternal sensitivity, maternal-child physiological attunement, and ultimately early childhood outcomes. To accomplish this, I need to acquire a fundamentally different skill set. My training plan is explicitly designed to address gaps in my knowledge of maternal attachment and its related biological processes (i.e., cortisol, oxytocin) that may compromise early childhood outcomes. Short-term training objectives include training in 1) biological measures of attachment and stress, 2) parent-child interaction assessment, 3) advanced training in treatment outcome research and related statistical analyses and, 4) skills requisite for a successful academic career (i.e., responsible conduct of research, grantsmanship, leading interdisciplinary teams). These training goals, together with the specific aims of the research plan, will lead to an R01 application, the theme of which will be incorporating the biological underpinnings of attachment into developing interventions to improve maternal attachment which will ultimately improve caregiving quality and early childhood outcomes. Throughout the mentored award period, the candidate will work under the supervision of Dr. Gayle Page, Johns Hopkins University, and Dr. Linda Bullock, the University of Virginia, experts in biobehavioral and maternal mental health research, respectively. The candidate will also receive mentorship from three senior consultants (Dr. Lane Strathearn, Dr. Lisa Berlin, Dr. Sharon Ghazarian) with complementary areas of expertise, carefully selected to address each of her training goals.

描述（由申请人提供）：这份 K23 申请为候选人 Jeanne Alhusen 博士做好了准备，她将从事研究密集型职业，领导多学科工作，以改善社区环境中早期干预计划所针对的儿童的早期儿童结局。母亲依恋的生物和心理基础及其对母婴生理协调以及最终儿童早期结果的影响的专家，从生物学的角度理解这些关系对于理解安全的母亲依恋如何赋予儿童发展优势至关重要。该提案的总体目标是（a）研究母亲皮质醇、催产素、依恋风格、敏感性之间的关系，（b）研究母亲的生物学行为的调节作用。母子皮质醇协调与母亲依恋风格和母亲敏感性之间的关系，以及（c）在短期内研究生活在城市贫困中的 75 名母子二人组中母子皮质醇协调与早期儿童结局之间的关系。目前的提案将使我获得技能和专业知识，以对母亲依恋的生物和心理基础及其与母亲敏感性、母子生理协调以及最终儿童早期结果的关系进行指导性研究。为了实现这一目标，我需要。我的培训计划明确旨在解决我对母性依恋及其相关生物过程（即皮质醇、催产素）的认识差距，这些差距可能会影响幼儿期的结果。 1）生物的依恋和压力的测量，2）亲子互动评估，3）治疗结果研究和相关统计分析的高级培训，4）成功学术生涯所需的技能（即负责任的研究行为、资助、领导跨学科团队）这些培训目标以及研究计划的具体目标将导致 R01 应用程序，其主题将是将依恋的生物学基础纳入制定干预措施以改善母亲依恋，从而最终提高护理质量和幼儿期在整个指导奖励期间，候选人将在约翰·霍普金斯大学盖尔·佩奇博士和弗吉尼亚大学琳达·布洛克博士的监督下工作，他们也分别接受生物行为和孕产妇心理健康研究专家的指导。由三位具有互补专业领域的高级顾问（Lane Strathearn 博士、Lisa Berlin 博士、Sharon Ghazarian 博士）组成，他们经过精心挑选来实现她的每个培训目标。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Integrative Review of Technology to Support Communication With Parents of Infants in the NICU.

支持新生儿重症监护室婴儿父母沟通的技术综合审查。

DOI：
发表时间：
2017
期刊：
影响因子：
0
作者：
Epstein, Elizabeth G;Arechiga, Jaqueline;Dancy, Margaret;Simon, Jordan;Wilson, Daniel;Alhusen, Jeanne L
通讯作者：
Alhusen, Jeanne L

Effects of Maternal Mental Health on Engagement in Favorable Health Practices During Pregnancy.

孕产妇心理健康对孕期良好健康习惯的影响。