Concordance Between Virtual and Clinical Measures of Child and Adult Height, Weight, and Neck Circumference: A Validity Sub-study (Jasmin Sanchez Diversity Supplement)

儿童和成人身高、体重和颈围的虚拟测量与临床测量之间的一致性：有效性子研究（Jasmin Sanchez 多样性补充）

• 批准号: 10711459
• 负责人: Jerica M Berge
• 金额: $ 8.58万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-15 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10711459
• 关键词: Adolescence; Adolescent; Adult; Age; Biological Markers; Body Composition; Body measure procedure; Buffers; Cardiometabolic Disease; Cardiovascular Diseases; Cardiovascular Physiology; Child; Child Behavior; Child Health; Child Rearing; Childhood; Clinical; Communities; Data; Diet; Disparity; Ecological momentary assessment; Environment; Exposure to; Family; Focus Groups; Food; Future; Geography; Health; Health Personnel; Health behavior; Height; Household; Individual; Inflammation; Information Services; Intervention; Knowledge; Life; Low income; Measures; Metabolic; Metabolic Diseases; Methodology; Methods; Neck; Neighborhoods; Oxidative Stress; Parents; Pathway interactions; Physical activity; Policies; Policy Developments; Prospective Studies; Resources; Risk; Risk Factors; Role; Schools; Science; Severities; Sleep; Stress; Surveys; Time; Weight; cardiometabolic risk; cardiometabolism; cohort; community organizations; coping; cytokine; ethnic diversity; feeding; food environment; food insecurity; improved; innovation; longitudinal, prospective study; obesity in children; prevent; prospective; protective factors; racial diversity; therapy development; virtual; Adolescence; Adolescent; Adult; Age; Biological Markers; Body Composition; Body measure procedure; Buffers; Cardiometabolic Disease; Cardiovascular Diseases; Cardiovascular Physiology; Child; Child Behavior; Child Health; Child Rearing; Childhood; Clinical; Communities; Data; Diet; Disparity; Ecological momentary assessment; Environment; Exposure to; Family; Focus Groups; Food; Future; Geography; Health; Health Personnel; Health behavior; Height; Household; Individual; Inflammation; Information Services; Intervention; Knowledge; Life; Low income; Measures; Metabolic; Metabolic Diseases; Methodology; Methods; Neck; Neighborhoods; Oxidative Stress; Parents; Pathway interactions; Physical activity; Policies; Policy Developments; Prospective Studies; Resources; Risk; Risk Factors; Role; Schools; Science; Severities; Sleep; Stress; Surveys; Time; Weight; cardiometabolic risk; cardiometabolism; cohort; community organizations; coping; cytokine; ethnic diversity; feeding; food environment; food insecurity; improved; innovation; longitudinal, prospective study; obesity in children; prevent; prospective; protective factors; racial diversity; therapy development; virtual

ABSTRACT (HL 160587) Food insecurity is known to be associated with metabolic and cardiovascular disease in adults. However, there is a gap in our knowledge; specifically a lack of studies investigating factors that influence the emergence of cardiometabolic risks from food insecurity during childhood and adolescence. An improved understanding of the role of timing and severity of food insecurity on children’s cardiometabolic health (CMH), the mechanisms/pathways between food insecurity and CMH, and the factors that buffer against or exacerbate this risk are needed to inform intervention development to prevent later cardiometabolic disease amongst children who are food insecure. The main objective of this prospective study is to understand how cardiometabolic risk arises from food insecurity during childhood and identify malleable factors for intervention to buffer the negative health impact of food insecurity on adolescent’s CMH. We will leverage an established cohort of racially/ethnically diverse children from low-income households (n=627) participating in a prospective, longitudinal study examining childhood obesity disparities (HL126171: Berge PI). Survey and ecological momentary assessment (EMA) data have already been collected, including measures of food insecurity, household environment (e.g., food environment, family functioning), child health behavior (e.g., diet quality, sleep, physical activity) and parent behaviors (e.g., feeding practices, stress, coping) at two time points (~24 months apart) at ages 5-10. New measures proposed at ages 11-16 will include: (1) measures of CMH (Life’s Simple 7 and state-of-the-science measures of body composition, metabolic and cardiovascular function, oxidative stress and inflammation (i.e., cytokines)), (2) Geographical Information Services (GIS) data, and (3) focus groups with families, school representatives, community organizations, and healthcare providers to identify intervention targets and refine policies to reduce harmful health effects of food insecurity. Specifically, this state-of-the art study will: (1) determine the impact of exposure to household food insecurity (i.e., severity, timing) on child/adolescent CMH; (2) identify mechanisms/pathways between food insecurity and CMH; (3) evaluate the extent to which child behaviors, parent factors, and access to resources impact the relationship between food insecurity and CMH; and (4) using mixed-methodologies (biomarkers, focus groups, EMA, GIS), prospectively examine the dynamics (e.g., severity, timing) of household food insecurity throughout childhood and adolescence, and identify risk and protective factors at the level of the family, neighborhood, school, and community to inform intervention and policy development. This approach is innovative because it represents a departure from the status quo by focusing on when and how cardiometabolic risk emerges from food insecurity during childhood and the multi-level factors which buffer against or exacerbate this risk, and significant because it is expected to have implications for intervention development to prevent future cardiometabolic diseases among adolescents from food insecure households.

摘要（HL 160587） 众所周知，粮食不安全与成年人的代谢和心血管疾病有关。但是，那里 在我们的知识上是一个差距；特别是缺乏研究影响影响因素的研究 儿童和青少年期间粮食不安全的心脏代谢风险。对 粮食不安全性的时间和严重性在儿童心脏代谢健康（CMH）中的作用， 粮食不安全与CMH之间的机制/途径，以及缓冲或加剧这一点的因素 需要风险来为干预开发提供信息，以防止儿童的后期心脏代谢疾病 粮食不安全。这项前瞻性研究的主要目的是了解心脏代谢的风险 儿童期间的粮食不安全产生，并确定可延展的因素以缓冲负面 粮食不安全对青少年CMH的健康影响。我们将利用已建立的队列 来自低收入家庭的种族/种族多元化儿童（n = 627）参加了前瞻性的， 纵向研究检查了儿童肥胖差异（HL126171：Berge PI）。调查与生态 瞬时评估（EMA）数据已经收集，包括粮食不安全的措施， 家庭环境（例如食品环境，家庭功能），儿童健康行为（例如，饮食质量， 睡眠，体育锻炼）和父行为（例如，喂养实践，压力，应对）在两个时间点（〜24） 相隔几个月）5-10岁。 11-16岁时提出的新措施将包括：（1）CMH的措施（生命的 简单的7和最先进的身体成分，代谢和心血管功能的措施， 氧化应激和炎症（即细胞因子）），（2）地理信息服务（GIS）数据，（3） 与家庭，学校代表，社区组织和医疗保健提供者的焦点小组 确定干预目标和完善政策，以减少粮食不安全的有害健康影响。具体来说， 这项最先进的研究将：（1）确定暴露于家庭粮食不安全的影响（即严重程度， 定时）在儿童/青少年CMH上； （2）确定粮食不安全与CMH之间的机制/途径； （3） 评估儿童行为，父母因素和获得资源的访问程度 在粮食不安全和CMH之间； （4）使用混合方法（生物标志物，焦点组，EMA，GIS）， 前瞻性地检查整个童年家庭粮食不安全的动态（例如严重性，时机） 和青少年，并确定家庭，邻里，学校和 为干预和政策制定提供信息的社区。这种方法具有创新性，因为它代表了 通过关注何时以及如何从粮食不安全感中出现心脏代谢风险来偏离现状 在童年时期和违反这种风险的缓冲或加剧的多层次因素，并且很大 因为预计它对干预开发有影响，以防止未来的心脏代谢 粮食不安全家庭的青少年疾病。