Biodiversity of Vietnam and Laos

越南和老挝的生物多样性

• 批准号: 6805154
• 负责人: DJAJA D SOEJARTO
• 金额: $ 85万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6805154
• 关键词: angiosperms; antiAIDS agent; antimalarial agents; antineoplastics; antitubercular agents; biomedical facility; chemoprevention; clinical research; cooperative study; culture; drug discovery /isolation; field study; folk medicine; geographic site; handbook; human subject; information systems; international cooperation; medicinal plants; plant ecology; sample collection; science education; southeast Asia; systematic biology

DESCRIPTION (provided by applicant): This proposed Phase II UIC ICBG (University of Illinois at Chicago-based ICBG) is a continuation of Phase I UIC ICBG, which has been in operation since October 1, 1998, until September 30, 2003. The specific aims of this proposed Phase II mirror those for Phase I, but with long-term second level achievements as follows: (i) integrated effort of biodiversity inventory and conservation at Cuc Phuong National Park (CPNP) in Vietnam, that will include the preparation of a Manual for taxonomic identification of the flowering plants in the park, the establishment of a Threatened Plants Rescue Center, the implementation of a conservation education program, and the transfer of GIS-based biodiversity assessment technology to Vietnam; (ii) integrated study of medicinal plants of Laos through the strengthening of the Lao Medicinal Plant Database and through a comparative ethnobotany mapping project in selected ecogeographic zones in Laos; (iii) collection of plant samples at CPNP and in Laos as an integral part of the UIC ICBG drug discovery effort during Phase II; (iv) expanded program in Phase II effort in the discovery and development of anti-HIV, anti-malaria, anti-TB, and cancer chemoptherapeutic and chemopreventive agents from plants of Vietnam and Laos; (v) setting up the infrastructure and the human resource for the preservation of traditional knowledge in the uses of plants in primary health care of local communities through the establishment of new and the upgrading of existing ethnomedical gardens established during Phase I; and, lastly, (vi) strengthening the capacity (institutional infrastructure and human resources) of host institutions in Vietnam and Laos, in higher level of expertise, to undertake research in biodiversity study and conservation, ethnobotany, and plant-based drug discovery far into the future, beyond ICBG. These specific aims are to be achieved through the close and synergistic cooperations of four Associate Programs (AP's), each with the following responsibility: (i) biodiversity inventory and conservation at CPNP (AP-1); studies on medicinal plants of Laos (AP-2); (iii) drug discovery from plants of Laos and Vietnam for AIDS, cancer, malaria and tuberculosis therapies (AP-3); and (iv) biomass production and economic development (AP-4). These four AP's will be coordinated by a Group Program, under the direction of the U C ICBG Principal Invest gator. The creation of the 4 AP's is necessary for the achievements of the specific aims as stated.

DESCRIPTION (provided by applicant): This proposed Phase II UIC ICBG (University of Illinois at Chicago-based ICBG) is a continuation of Phase I UIC ICBG, which has been in operation since October 1, 1998, until September 30, 2003. The specific aims of this proposed Phase II mirror those for Phase I, but with long-term second level achievements as follows: (i) integrated effort of biodiversity inventory and conservation at Cuc Phuong National Park （CPNP）在越南，这将包括准备公园中开花植物的分类学识别手册，建立受威胁的植物救援中心，实施保护教育计划以及将基于GIS的生物多样性评估技术转移到越南； （ii）通过加强老挝药物植物数据库的综合研究，以及通过老挝选定的生态地理区中的比较民族植物学映射项目； （iii）在CPNP和老挝收集了植物样品，这是II期UIC ICBG药物发现工作不可或缺的一部分； （iv）在第二阶段的努力中扩展了抗HIV，抗马拉里亚，抗-TB和癌症化学治疗和化学预防剂的抗HIV，抗Malaria，抗TB和越南植物植物的化学预防药物的计划； （v）建立基础设施和人力资源，以通过建立新的和升级在第一阶段建立的现有民族医学花园来维护传统知识在当地社区的初级卫生保健中使用传统知识；最后，（vi）越南和老挝的寄宿机构的能力（机构基础设施和人力资源）在更高水平的专业知识中，从事生物多样性研究和保护，民族植物学和植物性药物发现的研究，远远超过ICBG。这些具体目标将通过四个副计划（AP）的亲密和协同合作来实现，每个计划都承担以下责任：（i）CPNP（AP-1）的生物多样性清单和保护；对老挝药用植物（AP-2）的研究； （iii）从老挝和越南植物中发现艾滋病，癌症，疟疾和结核病疗法的药物（AP-3）； （iv）生物质生产与经济发展（AP-4）。这四个AP将由小组计划协调，在U C ICBG校长投资鳄鱼的指导下。对于所述的特定目的的成就，需要创建4个AP的创建。