Long-term trajectories of psychosocial functioning among transgender youth and their parents.

跨性别青少年及其父母心理社会功能的长期轨迹。

• 批准号: 10804174
• 负责人: Laura Elizabeth Kuper
• 金额: $ 62.08万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-25 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10804174
• 关键词: Address; Adolescence; Adult; Age; Automobile Driving; Caring; Characteristics; Child; Climate; Collaborations; Communities; Critiques; Data; Development; Distress; Enrollment; Estrogens; Family; Gender; Growth; Health Personnel; Health Services Accessibility; Individual; International; Knowledge; Literature; Location; Long-Term Effects; Longitudinal Studies; Measurement; Measures; Mental Health; Methods; Minor; Movement; Outcome; Parents; Pattern; Persons; Play; Policies; Politics; Process; Provider; Puberty; Quality of life; Regrets; Reporting; Research; Risk; Running; Sample Size; Social support; Statutes and Laws; Stress; Subgroup; Testosterone; Time; United States; Victimization; Youth; barrier to care; cohort; demographics; experience; follow-up; gender affirming care; gender affirming hormone therapy; gender diversity; gender dysphoria; gender minority stress; improved; minority stress; multidisciplinary; neglect; parental influence; parental role; personalized approach; personalized care; policy recommendation; programs; protective factors; psychosocial; puberty blocker; resilience; resilience factor; stress state; stressor; transgender; trend; Address; Adolescence; Adult; Age; Automobile Driving; Caring; Characteristics; Child; Climate; Collaborations; Communities; Critiques; Data; Development; Distress; Enrollment; Estrogens; Family; Gender; Growth; Health Personnel; Health Services Accessibility; Individual; International; Knowledge; Literature; Location; Long-Term Effects; Longitudinal Studies; Measurement; Measures; Mental Health; Methods; Minor; Movement; Outcome; Parents; Pattern; Persons; Play; Policies; Politics; Process; Provider; Puberty; Quality of life; Regrets; Reporting; Research; Risk; Running; Sample Size; Social support; Statutes and Laws; Stress; Subgroup; Testosterone; Time; United States; Victimization; Youth; barrier to care; cohort; demographics; experience; follow-up; gender affirming care; gender affirming hormone therapy; gender diversity; gender dysphoria; gender minority stress; improved; minority stress; multidisciplinary; neglect; parental influence; parental role; personalized approach; personalized care; policy recommendation; programs; protective factors; psychosocial; puberty blocker; resilience; resilience factor; stress state; stressor; transgender; trend

Project Summary/Abstract Over the past several years, concerns have escalated across the globe regarding the lack of knowledge about the long-term effects of gender-affirming hormone therapy (GAHT; puberty suppression, estrogen, testosterone) for transgender and gender diverse (TGD) youth, resulting in widespread legislation and policy recommendations restricting TGD youth’s access to this treatment. Simultaneously, research demonstrating short-term improvements in psychosocial functioning (e.g., mental health (MH) and quality of life (QoL)) among TGD youth receiving GAHT has been steadily accumulating and standards of care continue to support their use. Unfortunately, studies remain limited by short follow-up periods and small sample sizes. As the volume and diversity of youth presenting for care is growing, concerns over the stability of TGD youth’s identities and the likelihood they will regret treatment are also increasing. However, lack of research on within-group differences in TGD youth’s psychosocial trajectories while receiving GAHT leaves providers with little guidance on how to individualize care. More broadly, research is limited by poor measurement of gender dysphoria and lack of inclusion of minority stress and resilience (MSR) factors, which are particularly pronounced in the current sociopolitical climate. The functioning of parents of youth receiving GAHT has also been overlooked despite the critical role parents play in the mental health of TGD youth. The proposed project leverages the longest-running study of TGD youth receiving GAHT in the United States to address each of these critical gaps in the literature. This study is being conducted at the first and largest multidisciplinary gender-affirming care program for TGD youth in the Southwest US and has enrolled nearly 700 families since the program was founded in 2014. The aims of the project are to (1) characterize the 5- and 8-year trajectories of psychosocial functioning among TGD youth receiving GAHT (including gender dysphoria, MSR, MH, QoL) and their parents (including MSR and QoL), including how these trajectories influence each other over time, (2) identify and explore the characteristics of subgroups of individuals who share similar baseline and longitudinal experiences of gender dysphoria (youth) and MSR (youth, parents), and (3) assess the temporal relationships between MH (youth), QoL (youth and parents), and sociopolitical stress, including factors that moderate the impact of this unique form of stress. We will also explore the characteristics and trajectories of youth who experience changes in their gender and/or stop treatment. The project will be guided by a community-based participatory approach that will collaborate with TGD youth and their parents throughout the research process, including in the selection of additional measures to better capture gender dysphoria and sociopolitical stress. Given TGD youth are at heightened risk of experiencing a broad range of adverse psychosocial outcomes, identifying methods to relieve distress and promote healthy development is particularly urgent. The proposed project will provide critical empirical guidance on how to do so.

项目摘要/摘要 在过去的几年中，关于缺乏有关有关的知识的关注 性别疗法的马内治疗（Gaht;青春期抑制，雌激素，， 睾丸激素）针对跨性别和性别多样性（TGD）青年，导致了广泛的立法和政策 建议限制TGD青年获得此治疗的建议。同时，研究证明 短期改善社会心理功能（例如心理健康（MH）和生活质量（QOL）） 接收Gaht的TGD青年一直在悄悄地积累，护理标准继续支持他们的 使用。不幸的是，研究仍受到短时间的随访期和少量样本量的限制。作为音量 和护理的年轻人的多样性正在增长，对TGD青年身份的稳定和 他们会后悔治疗的可能性也在增加。但是，缺乏关于集团内部的研究 接收Gaht的TGD青年的心理社会轨迹的差异使提供者几乎没有指导 关于如何个性化护理。更广泛地，研究受到性别烦躁不良和 缺乏少数压力和韧性（MSR）因素，这在 当前的社会政治气候。接受Gaht的青年父母的运作也被忽略了 尽管父母在TGD青年的心理健康中起着至关重要的作用。提议的项目利用了 在美国接受GAHT的TGD青年进行的最长运行的研究以解决这些关键差距 在文献中。这项研究是在第一和最大的多学科性别肯定的护理中进行的 美国西南部的TGD青年计划，自该计划是该计划以来已经注册了近700个家庭 该项目的目的成立于2014年。 在接收Gaht的TGD青年中（包括性别烦躁不安，MSR，MH，QOL）和他们的父母 （包括MSR和QOL），包括这些轨迹如何随着时间的推移如何相互影响，（2）识别和 探索具有相似基线和纵向经验的个人亚组的特征 性别烦躁不安（青年）和MSR（青年，父母），以及（3）评估MH之间的临时关系 （青年），QoL（青年和父母）和社会政治压力，包括缓解这种影响的因素 独特的压力形式。我们还将探索经验丰富的年轻人的特征和轨迹 他们的性别和/或停止治疗的变化。该项目将以社区的参与为指导 在整个研究过程中，将与TGD青年及其父母合作的方法，包括 选择其他措施，以更好地捕捉性别烦躁不安和社会政治压力。给定TGD 年轻人面临着广泛的广告心理社会成果的风险，确定 缓解困扰和促进健康发展的方法尤其紧急。拟议的项目将 提供有关如何这样做的关键经验指导。