Medical Scientist National Research Service Award

医学科学家国家研究服务奖

• 批准号: 10703834
• 负责人: Marcus Ramsay Clark
• 金额: $ 127.72万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703834
• 关键词: Medical; National Research Service Awards; Scientist; Medical; National Research Service Awards; Scientist

PROJECT SUMMARY The mission of The University of Chicago (UChicago) Medical Scientist Training Program (MSTP) is to train the next generation of clinician-scientists for impactful careers in the biomedical sciences. Impact is broadly defined as: providing fundamental insights into disease and relevant biological mechanisms, leading or making substantial contributions to translational efforts to identify better therapies and/or filling leadership roles that will determine how limited resources can best be used to improve human health. Our overall objective is to train outstanding and self-directed clinician scientists who can formulate and answer biologically and medically- important questions. To ensure the greatest impact, our program must reflect the diversity of the U.S. population in both who it trains and who it serves. To accomplish our mission and overall objective, we defined 15 specific and measurable objectives that stress the technical, operational and professional skills that support science identity and self-efficacy and are critical for a successful career as an independent biomedical investigator. Two unique features of the program enable our mission and provide an optimal training environment for the development of clinician-scientists. First, we are our own graduate program, the Interdisciplinary Scientist Training Program (ISTP). The ISTP allows integration of graduate and medical school classes in MS1, development of tailored curricula for each trainee, coordination across training transitions and uniform oversight and expectations during the graduate phase. Second, most trainees pursue a 1-4-3 progression of study rather than the traditional 2-4-2 progression. While trainees may pursue a 2-4-2, the 1-4-3 provides a continuous and in-depth graduate experience where trainees become well-trained scientists who can propose and rigorously test hypotheses. The 1-4-3 also provides a seamless transition between the preclinical and clinical phases which facilitates overall success in medical school. Multiple programmatic features ensure that fundamental scientific and clinical knowledge are interwoven to foster the development of impactful clinician-scientists. The UChicago MSTP enjoys sustained and substantial University financial backing including generous direct investment and support of facilities that cultivate innovative science. We are requesting 25 training slots to supplement University investments to support trainees for six of the typical eight years they spend in the MSTP. This requested investment by the NIH would constitute only 13% of total anticipated cost for our MSTP. We anticipate a program size of approximately 80 trainees and expect, based on our track record, that our trainees will contribute significantly to the U.S. biomedical enterprise.

项目摘要 芝加哥大学（UCHICAGO）的任务医学科学家培训计划（MSTP）是培训 下一代生物医学科学有影响力职业的临床医生。影响很大 定义为：提供有关疾病和相关生物学机制的基本见解，领导或使 对转化努力的实质性贡献，以确定更好的疗法和/或填补领导角色 确定如何最好地使用有限的资源来改善人类健康。我们的总体目标是培训 杰出和自我指导的临床医生，他们可以在生物学上和医学上提出和回答 重要问题。为了确保最大的影响，我们的计划必须反映美国的多样性 它的训练及其服务的人的人口。为了实现我们的使命和整体目标，我们定义了 15强调支持技术，运营和专业技能的特定和可衡量的目标 科学的身份和自我效能感，对于成功的职业至关重要 研究者。该计划的两个独特功能使我们的任务并提供最佳培训 临床医生发展的环境。首先，我们是我们自己的研究生课程， 跨学科科学家培训计划（ISTP）。 ISTP允许整合研究生和医学 MS1的学校课程，为每个学员开发量身定制课程，跨培训的协调 在研究生阶段的过渡和统一的监督和期望。其次，大多数受训者追求 1-4-3研究的进展，而不是传统的2-4-2进展。虽然学员可以追求2-4-2，但 1-4-3提供了连续而深入的研究生经验，学员成为训练有素的科学家 谁可以提出并严格检验假设。 1-4-3还提供了 临床前和临床阶段促进了医学院的整体成功。多个程序化 功能确保基本的科学和临床知识交织在一起，以促进发展 有影响力的临床医生科学家。 Uchicago MSTP享有持续且实质性的大学财务 支持包括慷慨的直接投资和对培养创新科学的设施的支持。我们是 要求25个培训老虎机补充大学投资，以支持受训者典型的八名 他们在MSTP上花费了多年。 NIH要求的投资只占总数的13％ 我们的MSTP的预期成本。我们预计计划的规模约为80名，并且期望基于 根据我们的记录，我们的学员将为美国生物医学企业做出重大贡献。