Clinical and Translational Science Collaborative of Northern Ohio, Systems Marketing Analysis for Research Translation (SMART) Innovation Program

北俄亥俄州临床和转化科学合作组织研究转化系统营销分析 (SMART) 创新计划

• 批准号: 10703736
• 负责人: Brian Joseph Biroscak
• 金额: $ 72.46万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703736
• 关键词: Acceleration; Address; Advanced Development; Advocate; Area; Benchmarking; Calibration; Case Study; Clinical; Clinical Research; Clinical Sciences; Clinical effectiveness; Collaborations; Communities; Community Developments; Data; Dissemination and Implementation; Educational workshop; Effectiveness; Engineering; Equity; Goals; Health; Intervention; Investments; Lead; Marketing; Measurable; Methods; Modeling; Ohio; Outcome; Output; Patients; Performance; Phase; Process; Program Evaluation; Provider; Proxy; Public Health; Reduce health disparities; Research; Research Personnel; Research Project Grants; Risk; Services; Social Marketing; Speed; Structure; Suicide; System; Testing; Thinking; Translational Research; Translations; Violence; Work; beneficiary; clinical translation; commercialization; community setting; design; dynamic system; effective intervention; effectiveness research; evidence base; experience; follow-up; health care delivery; health disparity; health equity; health equity promotion; health inequalities; implementation context; implementation design; implementation outcomes; implementation strategy; improved; innovation; learning progression; manufacture; medication compliance; model building; models and simulation; novel; patient navigator; population health; programs; public health intervention; research study; scale up; screening; tool; translational research program

PROJECT ABSTRACT The Systems Marketing Analysis for Research Translation (SMART) Innovation Program brings a cutting- edge set of tools together to improve clinical and translational research effectiveness, efficiency, and equity and thereby enhance public health and health care delivery. The SMART Innovation Program supports CTSA Program Goals by (1) developing, demonstrating, and disseminating an operational innovation that improves the efficiency and effectiveness of clinical translational, (2) a structured, participatory method for promoting partnerships and collaborations to facilitate and accelerate translational research projects local, regionally, and nationally, and (3) creating and providing this with an explicit emphasis on addressing health disparities and deliver the benefits of translational science to all. More specifically, we build on our collective prior experience and collaboration combining community based-system dynamics as a participatory method for selection and tailoring of implementation strategies with a social marketing approach within a novel set-based concurrent engineering approach borrowed from manufacturing to accelerate translational research and health equity. Our primary hypothesis is that the integration of participatory system dynamics modeling with social marketing analysis improves clinical and translational research effectiveness, efficiency, and equity by reducing the complexity of translational research. The SMART Innovation program is designed to work with clinical researchers at any stage of the translational research continuum with an emphasis on the design of implementation strategies that maximize implementation outcomes of fidelity, reach, and sustainability of clinical interventions to promote health equity. More specifically, the SMART Innovation program begins with market analysis of the end user of the innovation (e.g., patient in the case of medication adherence, provider in the case of suicide screening and referral) to characterize the initial distribution of “demand” for the clinical innovation and its potential impact on reducing health inequities. This preliminary analysis provides the basis for a 2.5-day participatory group model building workshop with clinical researchers, implementation researchers, and end-users (or proxies, e.g., a patient navigator, advocate) to conceptualize the implementation context as a system, select and tailor implementation strategies, and refine an implementation. The program then supports the refinement of the analysis through a second phase of marketing analysis, leading to a more efficient translation of clinical and community innovations to improve health outcomes and health equity.

项目摘要 研究翻译系统营销分析 (SMART) 创新计划带来了前沿- 边缘工具集一起提高临床和转化研究的有效性、效率和公平性 从而加强公共卫生和医疗保健的提供。SMART 创新计划支持 CTSA。 计划目标是 (1) 开发、展示和传播可改善运营的创新 临床转化的效率和有效性，(2) 一种结构化的、参与性的促进方法 建立伙伴关系和协作，以促进和加速本地、区域和地区的转化研究项目 在全国范围内，(3) 制定和提供这一方案，并明确强调解决健康差距和 更具体地说，我们以我们之前的集体经验为基础。 和协作社区结合基于系统动力学作为选择和参与的参与方法 在新颖的基于集合的并发中使用社会营销方法定制实施策略 借鉴制造业的工程方法来加速转化研究和健康公平。 主要假设是参与系统动力学模型与社会营销的整合 分析通过减少 转化研究的复杂性。 SMART 创新计划旨在与处于任何阶段的临床研究人员合作 转化研究连续体，重点是设计实施策略，最大限度地发挥 临床干预措施的保真度、覆盖范围和可持续性的实施结果，以促进健康公平。 更具体地说，SMART 创新计划首先对创新的最终用户进行市场分析 （例如，在坚持服药的情况下为患者，在自杀筛查和转诊的情况下为提供者） 描述临床创新“需求”的初始分布及其对减少临床创新的潜在影响 该初步分析为 2.5 天的参与小组模型构建提供了基础。 与临床研究人员、研究人员实施和最终用户（或代理人，例如患者 导航者、倡导者）将实施环境概念化为一个系统，选择和定制实施 然后，该程序通过以下方式支持分析的细化。 营销分析的第二阶段，使临床和社区的转化更加有效 改善健康结果和健康公平的创新。