Toward Validating a Measure of Tonic and Phasic Irritability in Community and Clinical Samples

在社区和临床样本中验证强直性和阶段性烦躁性的测量

• 批准号: 10681607
• 负责人: Jamilah Silver
• 金额: $ 4.46万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10681607
• 关键词: 17 year old; 6 year old; Adolescence; Adolescent; Adult; Age; Anger; Area; Assessment tool; Attentional deficit; Behavioral Symptoms; Child; Child Rearing; Childhood; Clinic; Clinical; Communities; Data; Development; Disease; Equipment and supply inventories; Ethnic Origin; Etiology; Exhibits; Factor Analysis; Functional disorder; Generalized Anxiety Disorder; Goals; Grain; Hyperactivity; Impairment; Intervention; Interview; Literature; Longevity; Longitudinal Studies; Measurement; Measures; Mental Depression; Mental Health; Mental Health Services; Mental disorders; Methodology; Methods; Modeling; Moods; Onset of illness; Outcome; Outpatients; Parents; Participant; Patient Self-Report; Pattern; Phase; Population; Predictive Factor; Prevention approach; Process; Psychiatry; Psychology; Psychometrics; Psychopathology; Race; Reporting; Research; Research Personnel; Sampling; School-Age Population; Schools; Services; Severities; Structure; Substance Use Disorder; Surveys; Symptoms; Temperament; Testing; Validity and Reliability; Work; Youth; biological sex; cognitive interview; design; effective therapy; emotional symptom; follow up assessment; functional disability; functional outcomes; informant; instrument; longitudinal course; longitudinal dataset; negative affect; novel; prevent; psychologic; response; risk prediction; sound; suicidal; text searching; theories; therapy development; treatment response

Project Summary/Abstract Irritability is one of the most common mental health problems in children and adolescents. Moreover, it is one of the strongest predictors of later psychopathology and functional impairment in adulthood. Irritability can manifest in a variety of ways, which has recently led some investigators to conceptualize it as consisting of two components: tonic irritability, defined as persistently angry or grumpy mood; and phasic irritability, defined as short-lived temper outbursts. Though this distinction has been raised conceptually, research examining whether tonic/phasic irritability are empirically separable and differ in their clinical correlates, underlying mechanisms, longitudinal course, and treatment response is limited. A significant obstacle for empirical work in this area has been that no psychometrically validated measure that differentiates between tonic/phasic irritability is currently available for research or clinical use. Long-term objectives. I propose to develop and evaluate the first multi-informant measure of tonic/phasic irritability for school-age children and adolescents. This measure will fill an urgent gap in the literature by providing a psychometrically-sound, multi-informant instrument that will advance research on the etiopathogenesis of tonic/phasic irritability and help develop and evaluate targeted approaches to prevention and treatment. Design. I developed the tonic/phasic scale by 1) conducting a comprehensive literature search of existing instruments that cover related constructs, 2) utilizing experts in developmental psychopathology to revise and refine the item pool, and 3) conducting cognitive interviews with parents of children and adolescents using a combined think-aloud and debriefing methodology. The proposed project will collect data from five samples including three convenience community samples (a total of ~800 parents of 6–17-year-old children and ~800 unrelated 13–17-year-old youth) collected through Qualtrics XM panels, allowing for an iterative scale development process; a longitudinal dataset (~215 parents of 6-year-olds enriched for irritability) with a wider set of validating measures; and a clinical sample (~150 parents and their ~150 10–17-year-old children in outpatient psychology and psychiatry clinics) to evaluate the generalizability of the measure to a more severely impaired population. In each sample, participants will complete a brief survey assessing irritability and emotional and behavioral symptoms. Aims/Methods. The aims of this project are five-fold: 1) develop and refine a novel multi-informant scale for assessing youth tonic/phasic irritability using classical psychometric and item-response theory (IRT) analyses; 2) evaluate convergent and discriminant validity by examining concurrent relationships of tonic/phasic irritability with existing measures of irritability, parental psychopathology, parenting style, child temperament, and child psychopathology; 3) assess predictive validity by modeling relationships between tonic/phasic irritability and later measures of youth psychological problems; 4) evaluate measurement invariance for informant, age, biological sex, and race/ethnicity; and 5) develop a shortened version of the rating scale using IRT.

项目概要/摘要 烦躁是儿童和青少年最常见的心理健康问题之一。 成年后的精神病理学和功能障碍的最强预测因子可以。 以多种方式表现出来，最近一些研究人员将其概念化为由两个组成 成分：强直性烦躁，定义为持续愤怒或脾气暴躁的情绪；以及阶段性烦躁，定义为 尽管这种区别是在概念上提出的，但研究仍在进行检验。 强直性/阶段性烦躁是否在经验上是可分离的，并且其临床相关性是否不同，潜在的 机制、纵向病程和治疗反应是有限的，这是实证工作的一个重大障碍。 这个领域一直没有经过心理测量验证的措施来区分强直/阶段性 我建议制定和临床使用的长期目标。 评估学龄儿童和青少年的强直/阶段性烦躁的第一个多信息测量。 这项措施将通过提供心理测量学上合理的、多信息的方法来填补文献中的一个紧迫空白。 该仪器将推进强直/阶段性烦躁病因的研究，并帮助开发和 评估有针对性的预防和治疗方法 1) 对涵盖相关结构的现有工具进行全面的文献检索，2）利用 发展精神病理学专家修改和完善项目库，以及 3）进行认知 使用出声思考和汇报相结合的方法对儿童和青少年的父母进行访谈。 拟议项目将从五个样本收集数据，其中包括三个便利社区样本（一个 总共约 800 名 6-17 岁儿童的父母和约 800 名无亲属关系的 13-17 岁青少年）通过 Qualtrics XM 面板，允许迭代规模开发过程（约 215 个父母） 6 岁儿童因易怒而丰富），具有更广泛的验证措施和临床样本（约 150 个）； 心理和精神病学门诊的父母及其约 150 名 10-17 岁的孩子）来评估 该措施对更严重受损人群的普遍性。在每个样本中，参与者都会这样做。 完成一项评估烦躁以及情绪和行为症状的简短调查。 该项目有五个目标：1）开发和完善一种新颖的多信息量表来评估青少年 使用经典心理测量和项目反应理论 (IRT) 分析进行强直/阶段性烦躁 2) 评估； 通过检查强直/阶段性烦躁与 现有的易激惹、父母精神病理学、养育方式、儿童气质和儿童的衡量标准 精神病理学；3）通过模拟强直/阶段性烦躁和 青少年心理问题的后期测量；4）评估调查对象、年龄、 生物性别和种族/族裔；以及 5) 使用 IRT 制定简化版本的评级量表。