Core 02: Biostatistics, Epidemiology & Research Design Core

核心02：生物统计学、流行病学

• 批准号: 10677681
• 负责人: William Johnson
• 金额: $ 34.98万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677681
• 关键词: Address; Area; Award; Biometry; Center for Translational Science Activities; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communities; Community Outreach; Consultations; Data; Dedications; Development; Disparity; Education; Ensure; Epidemiology; Faculty; Feedback; Funding; Future; Goals; Grant; Health; Individual; Institution; Instruction; Investigation; Knowledge; Leadership; Location; Louisiana; Methodology; Outcome; Outcomes Research; Peer Review; Pilot Projects; Publications; Reduce health disparities; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resources; Scientific Advances and Accomplishments; Series; Services; Statistical Data Interpretation; Subgroup; System; Techniques; Training; Translational Research; Trust; Underrepresented Populations; Underserved Population; Vertebral column; Vision; Work; analytical method; citizen science; community based research; community engagement; design; health disparity; health equity promotion; high dimensionality; improved; interest; lectures; member; programs; quantitative imaging; social; sound; success; support network; translational scientist; transmission process; user-friendly; virtual

Project Summary: Biostatistics, Epidemiology & Research Design (BERD) CORE The overall goal of the Biostatistics, Epidemiology, and Research Design (BERD) Core of the Louisiana Clinical and Translational Science Center (LA CaTS) is to ensure that all clinical and translational research conducted within the purview of LA CaTS meets the highest scientific standards for study design and analysis. During the previous two funding periods, the BERD has successfully leveraged existing faculty expertise from the primary collaborating institutions and implemented an integrated BERD support network that is now available to investigators at all participating LA CaTS institutions. The BERD now provide services and consultation to investigators across the state including our Roadmap and Meritorious Scholars, and to other investigators seeking to expand their research toward translational efforts. The LA CATS leadership, and their respective institutions, provided considerable resources enabling the BERD Core to expand our biostatistics capacity, add additional epidemiology expertise, and provide unique proficiency in biostatistical approaches. As the comprehensive BERD resource for LA CaTS investigators, this core is one of the most requested services within the LA CaTS Center. For the upcoming cycle, we will expand our support network by the following Aims: Aim 1. Provide an easily accessible, user-friendly resource of biostatistics, epidemiology, and research design expertise for clinical and translational researchers, particularly those with projects focused on underserved and underrepresented populations throughout the state. The BERD will leverage its expertise to provide new resources such as high dimensional and quantitative imaging data, to ensure all LA CaTS researchers have ready access to statistical assistance as required. Aim 2. Participate in the education of future clinical and translational researchers by providing training in objective, good-practice, scientific investigation through study- design methodologies and quantitative statistical practices. The BERD Core will work closely with the Professional Development (PD) Core and the Community Engagement and Outreach (CEO) Core to educate researchers, citizen scientists, and community stakeholders on statistical concepts. Aim 3. Expand the knowledge and use of statistical analyses to ensure studies that address disparities and promote health equity are adequately designed and use statistically rigorous techniques. Coordinating closely with the Pilot Projects Program (PPP) Core, the BERD will ensure that every project has sound statistical rigor, including adequate power for subgroup analyses, and to address issues regarding health disparities. Thus, the BERD Core strives to collaborate with clinical and translational researchers across the state to advance scientific discoveries through sound statistical techniques.

项目摘要：生物统计学，流行病学和 研究设计（BERD）核心 路易斯安那州生物统计学，流行病学和研究设计（BERD）的总体目标 临床和转化科学中心（LA CATS）是为了确保所有临床和转化研究 在洛杉矶猫的范围内进行的符合研究设计和分析的最高科学标准。 在前两个资金期间，BERD成功地利用了现有的教师专业知识 主要的合作机构，并实施了一个集成的BERD支持网络，该网络现已可用 向所有参与的洛杉矶猫机构进行调查人员。 BERD现在提供服务和咨询 全州的调查人员，包括我们的路线图和有功学者，以及其他调查人员 试图将研究扩大到翻译工作。洛杉矶猫的领导及其各自的 机构提供了大量资源，使Berd核心能够扩大我们的生物统计学能力，并补充 其他流行病学专业知识，并提供了生物统计学方法的独特水平。作为 洛杉矶猫调查员的综合BERD资源是该核心是最需要的服务之一 洛杉矶猫中心。对于即将到来的周期，我们将以以下目的扩展我们的支持网络：目标1。 提供易于访问，用户友好的生物统计学，流行病学和研究设计专业知识的资源 对于临床和转化研究人员，特别是那些专注于服务不足的项目的研究人员 全州代表性不足。 BERD将利用其专业知识提供新的 诸如高维和定量成像数据之类的资源，以确保所有洛杉矶猫的研究人员都拥有 根据需要准备获得统计帮助。目标2。参加未来临床和 翻译研究人员通过研究提供客观，良好实践，科学研究的培训 - 设计方法和定量统计实践。 Berd核心将与 专业发展（PD）核心以及社区参与和外展（CEO）核心教育 研究人员，公民科学家和社区利益相关者统计概念。目标3。扩展 知识和使用统计分析，以确保解决差异和促进健康公平的研究 经过适当的设计并使用统计上严格的技术。与飞行员密切协调 项目计划（PPP）核心，BERD将确保每个项目都有明智的统计严格，包括 用于亚组分析的足够权力，并解决有关健康差异的问题。因此，Berd 核心努力与全州的临床和转化研究人员合作，以提高科学 通过合理的统计技术发现。