Core 02: Biostatistics, Epidemiology & Research Design Core

核心02：生物统计学、流行病学

• 批准号: 10677681
• 负责人: William Johnson
• 金额: $ 34.98万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677681
• 关键词: Address; Area; Award; Biometry; Center for Translational Science Activities; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communities; Community Outreach; Consultations; Data; Dedications; Development; Disparity; Education; Ensure; Epidemiology; Faculty; Feedback; Funding; Future; Goals; Grant; Health; Individual; Institution; Instruction; Investigation; Knowledge; Leadership; Location; Louisiana; Methodology; Outcome; Outcomes Research; Peer Review; Pilot Projects; Publications; Reduce health disparities; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resources; Scientific Advances and Accomplishments; Series; Services; Statistical Data Interpretation; Subgroup; System; Techniques; Training; Translational Research; Trust; Underrepresented Populations; Underserved Population; Vertebral column; Vision; Work; analytical method; citizen science; community based research; community engagement; design; health disparity; health equity promotion; high dimensionality; improved; interest; lectures; member; programs; quantitative imaging; social; sound; success; support network; translational scientist; transmission process; user-friendly; virtual

Project Summary: Biostatistics, Epidemiology & Research Design (BERD) CORE The overall goal of the Biostatistics, Epidemiology, and Research Design (BERD) Core of the Louisiana Clinical and Translational Science Center (LA CaTS) is to ensure that all clinical and translational research conducted within the purview of LA CaTS meets the highest scientific standards for study design and analysis. During the previous two funding periods, the BERD has successfully leveraged existing faculty expertise from the primary collaborating institutions and implemented an integrated BERD support network that is now available to investigators at all participating LA CaTS institutions. The BERD now provide services and consultation to investigators across the state including our Roadmap and Meritorious Scholars, and to other investigators seeking to expand their research toward translational efforts. The LA CATS leadership, and their respective institutions, provided considerable resources enabling the BERD Core to expand our biostatistics capacity, add additional epidemiology expertise, and provide unique proficiency in biostatistical approaches. As the comprehensive BERD resource for LA CaTS investigators, this core is one of the most requested services within the LA CaTS Center. For the upcoming cycle, we will expand our support network by the following Aims: Aim 1. Provide an easily accessible, user-friendly resource of biostatistics, epidemiology, and research design expertise for clinical and translational researchers, particularly those with projects focused on underserved and underrepresented populations throughout the state. The BERD will leverage its expertise to provide new resources such as high dimensional and quantitative imaging data, to ensure all LA CaTS researchers have ready access to statistical assistance as required. Aim 2. Participate in the education of future clinical and translational researchers by providing training in objective, good-practice, scientific investigation through study- design methodologies and quantitative statistical practices. The BERD Core will work closely with the Professional Development (PD) Core and the Community Engagement and Outreach (CEO) Core to educate researchers, citizen scientists, and community stakeholders on statistical concepts. Aim 3. Expand the knowledge and use of statistical analyses to ensure studies that address disparities and promote health equity are adequately designed and use statistically rigorous techniques. Coordinating closely with the Pilot Projects Program (PPP) Core, the BERD will ensure that every project has sound statistical rigor, including adequate power for subgroup analyses, and to address issues regarding health disparities. Thus, the BERD Core strives to collaborate with clinical and translational researchers across the state to advance scientific discoveries through sound statistical techniques.

项目摘要：生物统计学、流行病学和 研究设计 (BERD) 核心 路易斯安那州生物统计学、流行病学和研究设计 (BERD) 核心的总体目标 临床和转化科学中心 (LA CaTS) 旨在确保所有临床和转化研究 在 LA CatTS 的范围内进行的研究符合研究设计和分析的最高科学标准。 在前两个资助期间，BERD 成功地利用了来自以下机构的现有教师专业知识： 主要合作机构并实施了现已可用的综合 BERD 支持网络 所有参与 LA CatTS 机构的调查人员。 BERD 现在为以下人士提供服务和咨询： 全州的调查人员，包括我们的路线图和优秀学者，以及其他调查人员 寻求将他们的研究扩展到转化工作。 LA CATS 领导层及其各自的 机构，提供了大量资源，使 BERD 核心能够扩大我们的生物统计能力，添加 额外的流行病学专业知识，并提供生物统计方法的独特熟练程度。作为 为 LA CatS 调查人员提供全面的 BERD 资源，该核心是内部最需要的服务之一 洛杉矶 CatS 中心。对于即将到来的周期，我们将通过以下目标扩大我们的支持网络：目标 1。 提供易于访问、用户友好的生物统计学、流行病学和研究设计专业知识资源 对于临床和转化研究人员，特别是那些项目重点关注服务不足和 全州人口代表性不足。 BERD 将利用其专业知识提供新的 高维和定量成像数据等资源，以确保所有 LA CatTS 研究人员拥有 根据需要随时获得统计援助。目标 2. 参与未来临床和医学教育 转化研究人员通过研究提供客观、良好实践、科学研究的培训 设计方法和定量统计实践。 BERD 核心将与 专业发展 (PD) 核心和社区参与和外展 (CEO) 核心教育 研究人员、公民科学家和社区利益相关者了解统计概念。目标 3. 扩展 统计分析的知识和使用，以确保研究能够解决差异并促进健康公平 充分设计并使用严格的统计技术。与飞行员密切配合 作为项目计划 (PPP) 的核心，BERD 将确保每个项目都具有良好的统计严谨性，包括 足够的能力进行亚组分析，并解决有关健康差异的问题。因此，BERD Core 致力于与全州的临床和转化研究人员合作，推动科学发展 通过健全的统计技术发现。