Corepressor regulation of nuclear receptor action

核受体作用的辅阻遏物调节

• 批准号: 10562608
• 负责人: ANTHONY N HOLLENBERG
• 金额: $ 13.22万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10562608
• 关键词: Award; Cardiac Myocytes; Clinical; Foundations; Functional disorder; Gene Expression; Genes; Genome; Genomics; Heart; Hepatocyte; Human; Hyperthyroidism; Hypothyroidism; Lead; Liver; Mediating; Mediator of activation protein; Minor; Modeling; Molecular; Mus; NCOR1 gene; Nuclear; Nuclear Receptors; Nutritive Value; Parents; Play; Process; Protein Isoforms; Regulation; Research; Role; SMRT protein; Signal Transduction; Specificity; THRA gene; THRB gene; Testing; Thyroid Gland; Thyroid Hormone Receptor; Thyroid Hormones; Tissues; Tretinoin; cell type; genetic corepressor; genome wide association study; hormonal signals; hormone sensitivity; hypothalamic-pituitary-thyroid axis; insight; mouse model; novel; programs; receptor; receptor function; recruit; response; Award; Cardiac Myocytes; Clinical; Foundations; Functional disorder; Gene Expression; Genes; Genome; Genomics; Heart; Hepatocyte; Human; Hyperthyroidism; Hypothyroidism; Lead; Liver; Mediating; Mediator of activation protein; Minor; Modeling; Molecular; Mus; NCOR1 gene; Nuclear; Nuclear Receptors; Nutritive Value; Parents; Play; Process; Protein Isoforms; Regulation; Research; Role; SMRT protein; Signal Transduction; Specificity; THRA gene; THRB gene; Testing; Thyroid Gland; Thyroid Hormone Receptor; Thyroid Hormones; Tissues; Tretinoin; cell type; genetic corepressor; genome wide association study; hormonal signals; hormone sensitivity; hypothalamic-pituitary-thyroid axis; insight; mouse model; novel; programs; receptor; receptor function; recruit; response

Project Summary/Abstract As per the FOA, the project summary of the parent award has been included with the research plan.

项目摘要/摘要 根据FOA，研究计划已纳入了家长奖的项目摘要。