Oncopathology Training Program

肿瘤病理学培训计划

• 批准号: 10459400
• 负责人: JON C. ASTER
• 金额: $ 41.13万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-04 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10459400
• 关键词: Training Programs

PROJECT SUMMARY This is a new application for a Ruth L. Kirschstein National Research Service Award Institutional Research Training Grant (T32) to train post-doctoral trainees in the field of oncopathology, defined broadly as research that seeks to improve our understanding of cancer pathogenesis and pathobiology, and in doing so provide the basis for the development of new approaches that improve cancer diagnosis, prognostication, and treatment. The overall goal of the Oncopathology Training Program (OTP) is to provide research training opportunities across the full spectrum of oncopathology research, from basic study of cancer pathogenesis using the tools of cell and molecular biology, genomics, proteomics, animal modeling, and bioinformatics, to translational research that involves the development and deployment of biomarker tests and the use of digital and computational pathology, approaches that are increasingly important in cancer research. The training program is designed to benefit the research career development of M.D. and M.D./Ph.D. trainees subsequent to their training in clinical and/or anatomic pathology, and Ph.D. trainees with educational backgrounds in computational fields interested in the emerging area of computational pathology. Support is requested for 4 postdoctoral trainees in years 1-2, and 5 trainees in years 3-5. The training program includes structured elements such as individual development plans, mentored research experiences, and customizable didactic training opportunities as well as workshops in grant writing, manuscript composition, and lab management. Each trainee will have Postdoctoral Advisory Committee comprised of the Program Director, primary research mentor, and one or more senior cancer researchers with relevant expertise that will review trainee progress, provide advice and constructive criticism, and serve as a review committee for external fellowship proposals. The OTP faculty includes 24 highly accomplished investigators, with extensive mentoring track records and substantial extramural grant support, who constitute a highly collaborative mentoring community whose expertise span a wide-range of multidisciplinary, oncopathology-relevant areas, including animal modeling of cancer, cancer immunology, cancer genomics, computational pathology and tissue imaging, cancer diagnostics, and translational cancer informatics. The OTP will also take advantage of the extensive complement of scientific and educational resources that are available at Brigham and Women’s Hospital (BWH), Harvard Medical School (HMS). and Dana Farber Cancer Institute (DFCI), including the NCI-funded Dana-Farber/Harvard Cancer Center.

项目摘要 这是Ruth L. Kirschstein国家研究服务奖机构研究的新应用程序 培训补助金（T32）培训肿瘤病理学领域的博士后学员，被广泛定义为研究 旨在提高我们对癌症发病机理和病理生物学的理解，并这样做 开发改善癌症诊断，预后和治疗的新方法的基础。 肿瘤病理学培训计划（OTP）的总体目标是提供研究培训机会 在整个肿瘤病理学研究中，从癌症发病机理的基本研究使用 细胞和分子生物学，基因组学，蛋白质组学，动物建模和生物信息学，以翻译 涉及生物标志物测试的开发和部署以及数字和使用的研究 计算病理学，在癌症研究中越来越重要的方法。培训计划 旨在使M.D.和M.D./Ph.D的研究职业发展受益。后来的学员 临床和/或解剖病理学的培训以及博士学位。具有教育背景的学员 对计算病理学新兴领域感兴趣的计算领域。要求4 1 - 2年级的博士后学员，3 - 5年级的5名学员。培训计划包括结构化 诸如个人发展计划，指导的研究经验和可定制教学等要素 培训机会以及赠款写作，手稿组成和实验室管理的讲习班。 每个学员将在项目总监，主要研究的计划主任完成博士后咨询委员会委员会 导师和一名或多名高级癌症研究人员与相关专家，他们将审查受训者的进步， 提供建议和建设性的关键主义，并担任外部奖学金建议的审查委员会。 OTP教师包括24位高度成就的调查员，并具有广泛的心理记录和 大量的壁外赠款支持，他构成了一个高度协作的心态社区 专业知识涵盖了许多多学科，与肿瘤病理学相关的地区，包括动物建模 癌症，癌症免疫学，癌症基因组学，计算病理学和组织成像，癌症 诊断和翻译癌症信息。 OTP还将利用广泛的优势 杨百翰和妇女医院可用的科学和教育资源的补充 （BWH），哈佛医学院（HMS）。和Dana Farber癌症研究所（DFCI），包括NCI资助 达纳 - 法伯/哈佛癌中心。