Physiology-based virtual reality training for social skills in schizophrenia

基于生理学的虚拟现实精神分裂症社交技能训练

基本信息

  • 批准号:
    10229362
  • 负责人:
  • 金额:
    $ 53.2万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-03-01 至 2024-05-31
  • 项目状态:
    已结题

项目摘要

 DESCRIPTION (provided by applicant): Social impairments are core features of schizophrenia that lead to poor outcome. Social skills and competence improve quality of life and protect against stress-related exacerbation of symptoms, while supporting resilience, interpersonal interactions, and social affiliation. To improve outcome, we must remediate social deficits. Existing psychosocial interventions are moderately effective but the effort-intensive nature (high burden), low adherence, and weak transfer of skills to everyday life present significant hurdles toward recovery. Thus, there is a dire need to develop effective, engaging and low-burden social interventions for people with schizophrenia that will result in better compliance rates and functional outcome. We will test the effectiveness of a novel adaptive virtual reality (VR) intervention in improving targeted social cognitive function (social attention as indexed by eye scanning patterns) in individuals with schizophrenia. VR technology offers a flexible alternative to conventional therapies, with several advantages, including a simplified and low-stress social interaction environment with targeted opportunities to simulate, exercise and reinforce basic elements of social skills in a very wide range of realistic scenarios, and to repea exposure to naturalistic situations from multiple angles. Our desktop VR `game' is designed as an `intelligent' system that adaptively adjusts the difficulty of social training tasks based on participant's physiological, eye tracking and performance data in real time. Such dynamic feedback-based, `closed-loop' VR supports and enhances training because it adjusts and personalizes the learning environment in real time for each participant so that he/she always learns at an optimal arousal and attentional state. Furthermore, the VR environment can potentially simulate any social scenarios, which allows the participants to exercise social skills n a wide variety of situations. Such simulation exercises can help generalize learned skills to everyday life. The R21 phase will aim to implement the social intervention VR task, test its efficacy on improving social attention (target) in schizophrenia, and determine an optimal `dose'. We hypothesize that the VR training will engage social attention and improving social attention will lead to better social outcome. The R33 phase will test the adaptive social VR game against an active control condition in a pilot randomized controlled trial to evaluate the relative efficac of the social VR on enhancing social attention and associated neural circuitry. We will also examine social outcome. If this initial work is successful, our long-term goals are to develop VR social skills training modules that are personalized, accessible, and portable so that social remediation can become an integral part of one's daily life.
 描述(由申请人提供):社交障碍是精神分裂症的核心特征,会导致不良结果。社交技能和能力可以改善生活质量,防止与压力相关的症状恶化,同时支持恢复能力、人际交往和社会归属感。为了改善结果,我们必须纠正社会缺陷。现有的社会心理干预措施效果较好,但其工作强度大(负担高)、依从性低以及日常生活技能转移能力弱,给康复带来了重大障碍。因此,迫切需要为精神分裂症患者开发有效、有吸引力且低负担的社会干预措施,以提高依从率和功能结果。我们将测试新型自适应虚拟现实(VR)干预措施在改善方面的有效性。 VR 技术为精神分裂症患者提供了一种灵活的替代疗法,具有多种优势,包括简化和传统疗法。 低压力的社交互动环境,提供有针对性的机会,在广泛的现实场景中模拟、锻炼和强化社交技能的基本要素,并从多个角度重复接触自然场景。 “智能”系统可以根据参与者的生理、眼球追踪和实时表现数据自适应地调整社交训练任务的难度,这种基于动态反馈的“闭环”VR 支持和增强训练,因为它可以进行调整和个性化。为每个参与者提供实时的学习环境,使他/她始终处于最佳的唤醒和注意力状态下学习。此外,VR 环境可以模拟任何社交场景,使参与者能够在各种情况下锻炼社交技能。此类模拟练习可以帮助将学到的技能推广到日常生活中,目的是实施社会干预 VR 任务,测试其改善精神分裂症患者社会注意力(目标)的功效,并确定最佳“剂量”。 VR培训将R33 阶段将在一项试点随机对照试验中针对主动控制条件测试自适应社交 VR 游戏,以评估社交 VR 在增强社交注意力和相关方面的相对功效。我们还将检查社交结果。如果这项初步工作成功,我们的长期目标是开发个性化、易于访问和便携式的 VR 社交技能培训模块,以便社交矫正能够成为人们日常生活中不可或缺的一部分。生活。

项目成果

期刊论文数量(7)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Extraction of Emotional Information via Visual Scanning Patterns: A Feasibility Study of Participants with Schizophrenia and Neurotypical Individuals.
通过视觉扫描模式提取情感信息:精神分裂症和神经典型个体参与者的可行性研究。
  • DOI:
    10.1145/3282434
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    2.4
  • 作者:
    Wade,Joshua;Nichols,HeathmanS;Ichinose,Megan;Bian,Dayi;Bekele,Esube;Snodgress,Matthew;Amat,AshwaqZaini;Granholm,Eric;Park,Sohee;Sarkar,Nilanjan
  • 通讯作者:
    Sarkar,Nilanjan
Decoupling of spontaneous facial mimicry from emotion recognition in schizophrenia.
  • DOI:
    10.1016/j.psychres.2019.03.035
  • 发表时间:
    2019-05
  • 期刊:
  • 影响因子:
    11.3
  • 作者:
    Torregrossa LJ;Bian D;Wade J;Adery LH;Ichinose M;Nichols H;Bekele E;Sarkar N;Park S
  • 通讯作者:
    Park S
Improving treatments for psychotic disorders: beyond cognitive behaviour therapy for psychosis.
  • DOI:
    10.1080/17522439.2020.1742200
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    1.2
  • 作者:
    Nelson B;Torregrossa L;Thompson A;Sass LA;Park S;Hartmann JA;McGorry PD;Alvarez-Jimenez M
  • 通讯作者:
    Alvarez-Jimenez M
Cross-cultural comparisons of psychosocial distress in the USA, South Korea, France, and Hong Kong during the initial phase of COVID-19.
  • DOI:
    10.1016/j.psychres.2020.113593
  • 发表时间:
    2021-01
  • 期刊:
  • 影响因子:
    11.3
  • 作者:
    Dean DJ;Tso IF;Giersch A;Lee HS;Baxter T;Griffith T;Song L;Park S
  • 通讯作者:
    Park S
The acceptability and feasibility of a novel virtual reality based social skills training game for schizophrenia: Preliminary findings.
  • DOI:
    10.1016/j.psychres.2018.10.014
  • 发表时间:
    2018-12
  • 期刊:
  • 影响因子:
    11.3
  • 作者:
    Adery LH;Ichinose M;Torregrossa LJ;Wade J;Nichols H;Bekele E;Bian D;Gizdic A;Granholm E;Sarkar N;Park S
  • 通讯作者:
    Park S
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SOHEE PARK其他文献

SOHEE PARK的其他文献

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{{ truncateString('SOHEE PARK', 18)}}的其他基金

Spatial Self Boundary, Interpersonal Distance and Social Impairments in Schizophrenia
精神分裂症的空间自我边界、人际距离和社交障碍
  • 批准号:
    10674677
  • 财政年份:
    2022
  • 资助金额:
    $ 53.2万
  • 项目类别:
Spatial Self Boundary, Interpersonal Distance and Social Impairments in Schizophrenia
精神分裂症的空间自我边界、人际距离和社交障碍
  • 批准号:
    10374251
  • 财政年份:
    2022
  • 资助金额:
    $ 53.2万
  • 项目类别:
Physiology-based virtual reality training for social skills in schizophrenia
基于生理学的虚拟现实精神分裂症社交技能训练
  • 批准号:
    9228395
  • 财政年份:
    2016
  • 资助金额:
    $ 53.2万
  • 项目类别:
Physiology-based virtual reality training for social skills in schizophrenia
基于生理学的虚拟现实精神分裂症社交技能训练
  • 批准号:
    10011942
  • 财政年份:
    2016
  • 资助金额:
    $ 53.2万
  • 项目类别:
Physiology-based virtual reality training for social skills in schizophrenia
基于生理学的虚拟现实精神分裂症社交技能训练
  • 批准号:
    9570088
  • 财政年份:
    2016
  • 资助金额:
    $ 53.2万
  • 项目类别:
Restoring oscillations underlying adaptive control in schizophrenia with direct current
用直流电恢复精神分裂症自适应控制的振荡
  • 批准号:
    9764494
  • 财政年份:
    2016
  • 资助金额:
    $ 53.2万
  • 项目类别:
Restoring oscillations underlying adaptive control in schizophrenia with direct current
用直流电恢复精神分裂症自适应控制的振荡
  • 批准号:
    9344699
  • 财政年份:
    2016
  • 资助金额:
    $ 53.2万
  • 项目类别:
Physiology-based virtual reality training for social skills in schizophrenia
基于生理学的虚拟现实精神分裂症社交技能训练
  • 批准号:
    9019492
  • 财政年份:
    2016
  • 资助金额:
    $ 53.2万
  • 项目类别:
Etiology of Working Memory Deficit in Schizophrenia
精神分裂症工作记忆缺陷的病因学
  • 批准号:
    7147706
  • 财政年份:
    2006
  • 资助金额:
    $ 53.2万
  • 项目类别:
Etiology of Working Memory Deficit in Schizophrenia
精神分裂症工作记忆缺陷的病因学
  • 批准号:
    7897787
  • 财政年份:
    2006
  • 资助金额:
    $ 53.2万
  • 项目类别:

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