Molecular Neuroscience of Alcohol and Drug Abuse Research Training

酒精和药物滥用的分子神经科学研究培训

• 批准号: 10223173
• 负责人: Gary S. Aston-Jones
• 金额: $ 26.01万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10223173
• 关键词: Alcohol abuse; Drug abuse; Molecular; Neurosciences; Research Training

The Rutgers molecular neuroscience of alcohol and drug abuse research training (MNADRT) program in New Jersey is designed to promote the development of promising postdoctoral research fellows as independent investigators and future University faculty members who will investigate the pathogenesis of alcoholism and drug abuse. The MNADRT will emphasize a multidisciplinary approach including molecular and cellular techniques, electrophysiology, optogenetics, designer receptors exclusively activated by designer drugs, stem cell technology, neuroimaging, neuroimmunology, neurobehavioral pharmacology, and genetics to increase the understanding of pathogenesis in alcoholism and drug abuse. Training of the postdoctoral fellows will be individualized with the most important component being the research conducted by the trainee in the faculty mentor's laboratory. In addition to hands-on alcohol and drug abuse research, additional training will include seminars and conferences, grant writing, responsible conduct of research, teaching and mentoring, scientific rigor and reproducibility and other training as needed to prepare fellows for independent research. The training faculty will consist of 10 funded investigators from multiple departments at Rutgers University. The trainees will benefit from the unique strengths of alcohol and drug abuse research at Rutgers University, which include the Endocrine Research Program, Brain Health Institute, Center of Alcohol Studies, and the research cores, including genome editing core facility, bioimaging core facility, genomic informatics and biostatics services. The vast resources of Rutgers provide state-of-the-art space, laboratory facilities, and equipment that support exceptional postdoctoral training. The training program will be directed by Drs. Dipak K. Sarkar and. Gary Aston-Jones and assisted by the Internal Advisory Committee consisted of 3 senior faculty members. Broader scientific inputs to the training will be provided by an External Advisory Committee consisting of four well- known alcohol and drug abuse researchers, Drs. Fulton Crews, Paula L. Hoffman, Fernando Valenzuela and Regina M. Carelli, who have substantial knowledge in NIAAA/NIDA training of postdoctoral fellows. The program proposes four post-doctoral fellow slots. Trainees will receive two years of research training and with external support sought for later years. This institutional training grant will promote intensive training in molecular, cellular, immunological, stem cell technology, imaging techniques and basic neuroscience and neuroendocrinology in a stimulating environment leading to broadly trained independent investigators capable of adapting to the rapid advances in research in the 21st century.

罗格斯大学酒精和药物滥用分子神经科学研究培训 (MNADRT) 项目 泽西岛旨在促进有前途的博士后研究员作为独立的发展 研究人员和未来的大学教员将研究酗酒的发病机制和 药物滥用。 MNADRT 将强调多学科方法，包括分子和细胞 技术、电生理学、光遗传学、仅由设计药物激活的设计受体、干细胞 细胞技术、神经影像学、神经免疫学、神经行为药理学和遗传学，以增加 了解酗酒和药物滥用的发病机制。博士后培训将在 个性化，最重要的组成部分是学院实习生进行的研究 导师的实验室。除了酒精和药物滥用研究的实践之外，额外的培训还包括 研讨会和会议、拨款写作、负责任的研究、教学和指导、科学 严谨性和可重复性以及为研究员进行独立研究做好准备所需的其他培训。培训内容 教员将由来自罗格斯大学多个系的 10 名受资助的研究人员组成。学员们将 受益于罗格斯大学酒精和药物滥用研究的独特优势，其中包括 内分泌研究计划、脑健康研究所、酒精研究中心和研究核心， 包括基因组编辑核心设施、生物成像核心设施、基因组信息学和生物统计学服务。这 罗格斯大学的丰富资源提供了最先进的空间、实验室设施和设备，支持 特殊的博士后培训。培训计划将由博士指导。迪帕克·K·萨卡 (Dipak K. Sarkar) 和。加里 阿斯顿琼斯由 3 名高级教职人员组成的内部咨询委员会协助。更广泛的 外部咨询委员会将向培训提供科学投入，该委员会由四位资深人士组成 已知的酒精和药物滥用研究人员，博士。富尔顿·克鲁斯、保拉·L·霍夫曼、费尔南多·巴伦苏埃拉和 Regina M. Carelli，在 NIAAA/NIDA 博士后培训方面拥有丰富的知识。这 该计划提出了四个博士后研究员名额。学员将接受两年的研究培训并 随后几年寻求外部支持。该机构培训补助金将促进强化培训 分子、细胞、免疫学、干细胞技术、成像技术和基础神经科学和 神经内分泌学在一个刺激的环境中，导致训练有素的独立研究人员有能力 适应21世纪研究​​的快速发展。