CareBand: A Collaborative Pilot Study to Optimize a Life-Space Performance Metric for Monitoring and Early Detection of Alzheimer's Disease and Related Dementias in Rural and Indigenous Communities

CareBand：一项合作试点研究，旨在优化生活空间绩效指标，以监测和早期发现农村和土著社区的阿尔茨海默病和相关痴呆症

• 批准号: 10212745
• 负责人: Wayne Richard Warry
• 金额: $ 43.87万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10212745
• 关键词: Address; Aging; Algorithmic Analysis; Algorithms; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Behavior; Caregiver Burden; Caregivers; Caring; Cellular Phone; Cognitive; Communities; Complement; Data; Data Set; Dementia; Dementia caregivers; Development; Devices; Diagnosis; Early Diagnosis; Ensure; Environment; Ethics; Frequencies; Geography; Goals; Gold; Home; Impaired cognition; Incidence; Indigenous; Industry; Internet; Interview; Learning; Life; Life Style; Location; Measures; Medical; Memory; Minnesota; Monitor; Movement; Native-Born; Patient Self-Report; Performance; Persons; Physical environment; Pilot Projects; Population; Population Heterogeneity; Prevalence; Privatization; Reporting; Research; Research Personnel; Rural; Rural Community; Rural Population; Sampling; Services; Social Environment; Speed; System; Technology; Time; Translating; Uncertainty; Universities; age related; aging in place; base; clinical predictors; clinically relevant; community based participatory research; cost effective; data modeling; diaries; experience; falls; health care availability; health care service; health disparity populations; health equity; improved; indigenous community; industry partner; innovation; movement analysis; pre-clinical; rurality; sensor; technology development; validation studies; wearable device

Project Summary/Abstract Despite having higher rates of ADRD, increased caregiver stress and a lack of accessible healthcare services compared to urban counterparts, rural and Indigenous populations are grossly underrepresented in dementia research, especially in technology development. This R21 project, titled CareBand: A Collaborative Pilot Study to Optimize a Life-Space Performance Metric for Monitoring and Early Detection of ADRD in Rural and Indigenous Communities addresses urgent dementia disparities by developing aging-in-place technology to monitor dementia-related behaviours. This project brings together the University of Minnesota’s Memory Keepers - Medical Discover Team (MK-MDT) with an Industry partner, CareBand Inc., to digitize and expand existing metrics for the recording and analysis of movement through personal (in-home) and community environments, called life-space, using CareBand’s already available and proven, unobtrusive wearable wristband device. CareBand uses LoRa technology making it accessible to those without Internet or cellular services. This research will develop a new metric, a life-space performance (LSP) score, that will capture mobility through the exact calculation of distance based on amount, frequency and speed and as well as quality of movements (stability, falls, speed) across any clinically relevant period of time. Our long-term goal is to use LSP metrics to track cognitive decline from pre-clinical subjective cognitive complaints through all stages of ADRD among geographically and culturally diverse populations. Our overall hypothesis is that culture and geography are significant factors in determining one’s life-space and that the accurate measure of LSP in Indigenous and rural populations can be achieved by developing measures that account for their unique contexts. Using a community-based participatory research approach, we will partner with Indigenous and rural communities to pilot CareBand allowing us to collect data on rural and Indigenous life-space utilization to produce a LSP score that will benefit PWD and their caregivers. Our research has three specific aims. First, we will conduct depth interviews to generate qualitative data to inform the LSP data model by identifying and prioritizing the most critical life-space behaviors for directing care decisions. Second, the CareBand will be piloted for 12 weeks in rural and Indigenous with 20 People with Dementia caregivers, to capture location, movement and speed of movement inside and outside the home. Third, we will develop a set of algorithms by analyzing the qualitative and quantitative results captured in Aims 1 and 2 to create an LSP Score. This research will digitize life-space measures into a LSP score which includes indicators appropriate to rural and Indigenous populations and will lay the groundwork for a subsequent R01 application to validate the context specific LSP metrics against existing gold standards. The culturally appropriate LSP measure will contribute to health equity through improved early detection, diagnosis and care for rural and Indigenous populations.

项目概要/摘要 尽管 ADRD 发生率较高，但护理人员压力增加且缺乏可获得的医疗服务 与城市捐助者相比，农村和原住民患痴呆症的人数严重不足 研究，特别是在技术开发方面，这个 R21 项目名为 CareBand：协作试点研究。 优化生活空间绩效指标，以监测和早期发现农村和农村地区的 ADRD 原住民社区通过开发就地老龄化技术来解决紧迫的痴呆症差异 该项目汇集了明尼苏达大学的记忆中心。 Keepers - Medical Discover Team (MK-MDT) 与行业合作伙伴 CareBand Inc. 一起进行数字化和扩展 用于记录和分析个人（家庭）和社区运动的现有指标 环境，称为生活空间，使用 CareBand 已经可用且经过验证的、不引人注目的可穿戴设备 CareBand 使用 LoRa 技术，让那些没有互联网或蜂窝网络的人也能使用它。 这项研究将开发一个新的指标，即生活空间绩效（LSP）分数，该指标将捕获服务。 通过基于数量、频率和速度精确计算距离以及以及 我们的长期目标是在任何临床相关时间段内的运动质量（稳定性、跌倒、速度）。 使用 LSP 指标来跟踪临床前主观认知主诉的认知下降 我们的总体假设是，文化是 ADRD 的不同阶段。 地理和地理是决定一个人的生活空间的重要因素，并且LSP的准确测量 土著和农村人口可以通过制定考虑到其独特性的措施来实现 我们将采用基于社区的参与性研究方法，与土著和农村地区合作。 社区试点 CareBand 使我们能够收集有关农村和原住民生活空间利用的数据 产生有利于残疾人及其护理人员的 LSP 分数 我们的研究有三个具体目标。 将进行深度访谈以生成定性数据，通过识别和分析为 LSP 数据模型提供信息 优先考虑最关键的生活空间行为来指导护理决策 其次，CareBand 将是。 在农村和原住民中，由 20 名痴呆症患者护理人员进行了 12 周的试点，以捕捉位置、 第三，我们将开发一套算法。 分析目标 1 和 2 中捕获的定性和定量结果以创建 LSP 分数。 研究将把生活空间衡量数字化为 LSP 分数，其中包括适合农村和农村地区的指标 原住民，并将为后续 R01 申请验证背景奠定基础 针对现有黄金标准的具体 LSP 指标 适合文化的 LSP 衡量标准将有助于 通过公平改善健康状况，改善农村和土著居民的早期发现、诊断和护理。