Administrative Core A

行政核心A

基本信息

批准号：
10388086
负责人：
GERARD DAVID SCHELLENBERG
金额：
$ 52.04万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-04-15 至 2026-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10388086
关键词：
Abbreviations Alzheimer&apos s Disease Alzheimer&apos s Disease Core Center Alzheimer&apos s disease related dementia Artificial Intelligence Award Chromatin Collaborations Communities Consent Data Data Analyses Data Protection Data Set Development Disease Documentation Ensure Epigenetic Process European Fostering Frontotemporal Dementia Funding Genetic Genetic Diseases Genome Genomics Grant Health Sciences Institution Institutional Review Boards International Joints Lead Lewy Body Disease Machine Learning Meta-Analysis Methods Molecular Molecular Conformation National Institute on Aging Newsletter Paralysed Parkinson&apos s Dementia Pathogenesis Pick Disease of the Brain Principal Investigator Process Progressive Supranuclear Palsy Proteomics Protocols documentation Provider Publications Quality Control Reporter Research Research Personnel SNP array Schedule Site Source Systems Analysis Teleconferences Telephone United States National Institutes of Health University Health Services Variant Work cognitive system computerized data processing corticobasal degeneration dashboard data harmonization data sharing data storage site database of Genotypes and Phenotypes deep learning deep neural network exome follow-up functional genomics gene discovery genomic data meetings member metabolomics neural network neuroimaging phenotypic data single-cell RNA sequencing symposium trait web site whole genome working group

Abbreviations Alzheimer&apos s Disease Alzheimer&apos s Disease Core Center Alzheimer&apos s disease related dementia Artificial Intelligence Award Chromatin Collaborations Communities Consent Data Data Analyses Data Protection Data Set Development Disease Documentation Ensure Epigenetic Process European Fostering Frontotemporal Dementia Funding Genetic Genetic Diseases Genome Genomics Grant Health Sciences Institution Institutional Review Boards International Joints Lead Lewy Body Disease Machine Learning Meta-Analysis Methods Molecular Molecular Conformation National Institute on Aging Newsletter Paralysed Parkinson&apos s Dementia Pathogenesis Pick Disease of the Brain Principal Investigator Process Progressive Supranuclear Palsy Proteomics Protocols documentation Provider Publications Quality Control Reporter Research Research Personnel SNP array Schedule Site Source Systems Analysis Teleconferences Telephone United States National Institutes of Health University Health Services Variant Work cognitive system computerized data processing corticobasal degeneration dashboard data harmonization data sharing data storage site database of Genotypes and Phenotypes deep learning deep neural network exome follow-up functional genomics gene discovery genomic data meetings member metabolomics neural network neuroimaging phenotypic data single-cell RNA sequencing symposium trait web site whole genome working group

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项目摘要

Core A Project Summary/Abstract Core A (Administrative Core) will oversee, facilitate and coordinate all GCAD activities carried out by the other two cores. Core A will also coordinate analyses by investigators funded to analyze Alzheimer’s Disease Sequencing Project (ADSP) data. Core A Specific Aims are: (1) Coordinate acquisition of ADRD genetic, FG, and phenotype data; (2) Coordinate data processing, harmonization and analyses; (3) Support/foster collaboration between ADSP investigators and related projects; (4) Disseminate data and findings to a diverse group of ADRD researchers; (5) Provide administrative support to GCAD including governance, Institution Review Board (IRB) protocol review, and data sharing compliance.

核心项目摘要/摘要核心A（行政核心）将监督，促进和协调所有GCAD活动由其他两个核心出来。核心A还将协调资助的调查人员的分析分析阿尔茨海默氏病测序项目（ADSP）数据。核心一个具体目标是：（1）协调ADRD遗传，FG和表型数据的采集；（2）协调数据处理，协调和分析；（3）ADSP之间的支持/寄养协作调查人员及相关项目；（4）将数据和调查结果传播给一组不同的ADRD 研究人员；（5）为GCAD提供行政支持，包括治理，机构审查委员会（IRB）协议审查和数据共享合规性。