Predoctoral Training Program in Biotechnology

生物技术博士前培训计划

基本信息

批准号：
10200820
负责人：
Robert John Kerns
金额：
$ 21.3万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
1990
资助国家：
美国
起止时间：
1990-07-01 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10200820
关键词：
Biotechnology Training Programs pre-doctoral

项目摘要

Project Summary This application requests continued support for 6 trainees for a Predoctoral Training Program (TP) in Biotechnology that was first funded in 1990. If granted, these 6 lines will be matched by 6 more lines by the University of Iowa, through its Center for Biocatalysis and Bioprocessing (CBB). The CBB will also continue to provide the administrative and additional financial. This institutional match will allow the TP to select a yearly cohort of 12 predoctoral students. The CBB will also provide administrative assistance and training in industrial settings and will expose trainees to commercial aspects of biotechnology. This matching support will greatly increases the effectiveness of the funds requested from NIH and assures an extensive industrial emphasis in training. The TP is designed to provide a deep and diverse education to trainees, including academic training covering qualitative and quantitative aspects of biotechnology, hands- on introduction to industrial methods, and preparation for professional life in biotechnology. Trainees are required to: a) complete an industrial internship for three months; b) take at least one course in each of the three core areas of biotechnology (Biocatalysis, Bioreactors & Bioseparations, Molecular Biology & Genetics); c) take the program's capstone course, “Introduction to Biocatalysis”; d) take a course in Responsible Conduct of Research; e) participate in the “Perspectives in Biocatalysis” class and activities every semester; f) participate in TP's Seminars; g) present research in an annual Biocatalysis and Bioprocessing Conference and the annual TP symposium; and h) participate in various trainee-cohort social and networking activities. Candidates are selected toward the end of their first year in graduate school, and support for trainees may be renewed for up to two years, however all trainees continue in the program until graduation. The recruiting pool is based not on departmental affiliation but on interest in biotechnology, graduate training. Currently 33 trainers from four different colleges, and two interdisciplinary PhD programs participate in this TP. The diverse trainers cohort, together with the CBB partnership, provides trainees with a broad training experience including significant exposure to non-academic career paths. The TP is administered by a Leadership Team (a PI and three Co-PIs) and an Executive Committee. An External Review Panel provides independent input to assure relevance to the leadership and training needs of Biotech industry and research.

项目摘要该申请要求继续支持6名学员进行培训前培训生物技术的计划（TP）于1990年首次资助。如果被授予，这6行将由爱荷华大学通过其生物催化中心搭配6条线和生物处理（CBB）。 CBB还将继续提供行政和额外的财务。这项机构比赛将使TP能够选择一年一度的队列 12名学生。 CBB还将提供行政援助，在工业环境中培训，将使受训人员接触到生物技术。这种匹配的支持将大大提高 NIH要求的资金并承担了培训的广泛工业重点。 TP旨在为受训者提供深厚的多元化教育，包括学术培训涵盖生物技术的定性和定量方面关于工业方法的介绍，并为职业生涯做准备生物技术。需要学员必须：a）完成三个工业实习月份； b）在生物技术的三个核心领域中，至少要参加一门课程（生物催化，生物反应器和生物序列，分子生物学和遗传学）； c）拿程序的顶峰课程，“生物催化概论”； d）参加课程负责任的研究； e）参与“生物催化的观点” 每个学期的课堂和活动； f）参加TP的研讨会； g）目前的研究在年度生物催化和生物处理会议和年度TP研讨会上； h）参加各种受训者 - 霍特社会和网络活动。候选人在研究生院第一年结束时被选中，对学员的支持可能会续签长达两年，但是所有受训者仍在继续在计划直到毕业。招聘池不是基于部门会员，但对生物技术，研究生培训感兴趣。目前有33名培训师来自四个不同的大学和两个跨学科博士学位课程参加了该TP。这潜水员培训师队列以及CBB合作伙伴关系，为培训提供了广泛的培训经验，包括大量接触非学术职业道路。 TP由领导团队（PI和三个共同提议）和高管管理委员会。外部审核面板提供了独立的输入以确保相关性满足生物技术行业和研究的领导和培训需求。

项目成果

期刊论文数量（163）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Miniaturization of gene transfection assays in 384- and 1536-well microplates.

384 孔和 1536 孔微孔板中基因转染测定的小型化。

DOI：
10.1016/j.ab.2014.10.001
发表时间：
2015
期刊：
Analytical biochemistry
影响因子：
2.9
作者：
Li,Jing;Crowley,SamuelT;Duskey,Jason;Khargharia,Sanjib;Wu,Meng;Rice,KevinG
通讯作者：
Rice,KevinG

Organic nanocrystals of the resorcinarene hexamer via sonochemistry: evidence of reversed crystal growth involving hollow morphologies.

DOI：
10.1021/ja211141p
发表时间：
2012-04-25
期刊：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
影响因子：
15
作者：
Sander, John R. G.;Bucar, Dejan-Kresimir;Baltrusaitis, Jonas;MacGillivray, Leonard R.
通讯作者：
MacGillivray, Leonard R.

The Escherichia coli cell division protein and model Tat substrate SufI (FtsP) localizes to the septal ring and has a multicopper oxidase-like structure.

DOI：
10.1016/j.jmb.2008.12.043
发表时间：
2009-02-20
期刊：
JOURNAL OF MOLECULAR BIOLOGY
影响因子：
5.6
作者：
Tarry, Michael;Arends, S. J. Ryan;Roversi, Pietro;Piette, Evan;Sargent, Frank;Berks, Ben C.;Weiss, David S.;Lea, Susan M.
通讯作者：
Lea, Susan M.

Fluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg(2+) to the second metal binding site.

氟喹诺酮类药物通过促进 Mg(2) 与第二个金属结合位点的结合来刺激拓扑异构酶 IV 的 DNA 切割活性。