Workshops of the National Academies Roundtable on Science and Welfare in Laboratory Animal Use (ILAR Roundtable)

美国国家科学院实验动物使用科学与福利圆桌会议研讨会（ILAR 圆桌会议）

• 批准号: 10192673
• 负责人: Teresa Sylvina
• 金额: $ 2万
• 依托单位: NATIONAL ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10192673
• 关键词: Workshops; National; Academies; Roundtable; Science

PROJECT SUMMARY/ABSTRACT Application Title: Workshops of the National Academies' Roundtable on Science and Welfare in Laboratory Animal Use (ILAR Roundtable) Funding Opportunity Title: FDA Scientific Conference Grant Program (R13); PAR-19-306. This request is for funding from the Office of the FDA Commissioner (OC/OCS/OCET). The Institute for Laboratory Animal Research (ILAR) of the National Academies of Sciences, Engineering, and Medicine established the Roundtable on Science and Welfare in Laboratory Animal Use in the Fall of 2013. The purpose of the Roundtable is to foster communication and problem solving among the many different constituencies with strong interests in the use and welfare of laboratory animals in research and testing, including, government agencies, pharmaceutical and consumer product corporations, vendors, animal advocacy groups, professional societies, and academic institutions , including scientists and veterinarians. The workshops will be open to the public and webcasted, and there will be no fee charged to attend or view the workshop via the web. This application requests funds from the U.S. Food and Drug Administration to provide partial support toward convening up to two workshops a year, beginning in 2020 for a period of five years under the auspices of the Roundtable. Each workshop will focus on a critical issue related to the science and welfare of laboratory animal use, such as Micro-Physiological Systems for Efficacy and Safety Studies: A Workshop on Advances in Organs-On-Chip Technologies for Animals; The 4th R: Rehoming and Retirement of Non-Human Primates Used in Research; the Ethics and Use of Genetic Modifications in Xenotransplantation; and Laboratory Animal Use and the One Health Paradigm. The workshops present opportunities for 1) outreach to and dialogue with all communities who share an interest in the use of laboratory animals in research; 2) sharing of cutting-edge scientific information; and 3) increased understanding of the topics and identification of possible follow-on activities to improve the quality of biomedical research and laboratory animal welfare. Animal-based research is a fundamental component of the preclinical research and development and proof-of-concept studies of drugs, biologics and medical devices. Ensuring the highest quality of these studies while maintaining appropriate care and use of the animals used depends on building trust and maintaining and information sharing among the research, scientific and veterinary medical communities. As such, the purpose of Roundtable and its workshops is consistent with the mission of the FDA: "…protecting the public health by assuring the safety, efficacy and security of human and veterinary drugs, biological products, medical devices, our nation's food supply, cosmetics, and products that emit radiation”.

项目摘要/摘要 申请标题：国家学院的科学与福利圆桌会议讲习班 在实验室动物使用中 资金机会名称：FDA科学会议赠款计划（R13）； Par-19-306。 此请求是向FDA专员办公室（OC/OCS/OCET）提供资金。 美国国家科学学院实验室动物研究所（ILAR）， 工程和医学建立了实验室科学和福利的圆桌会议 动物在2013年秋天使用。圆桌会议的目的是促进交流 以及在使用强烈兴趣使用的许多不同选区之间解决问题的问题 以及在包括政府机构在内的研究和测试中实验动物的福利， 药品和消费产品公司，供应商，动物倡导团体， 专业社会和学术机构，包括科学家和兽医。 研讨会将向公众开放和网络播放，并且不会收取任何费用来参加 或通过网络查看研讨会。 该申请要求美国食品药品监督管理局的资金提供部分 从2020年开始召集多达两次研讨会的支持，为期五个 在圆桌会议的主持下。每个研讨会将重点介绍与关键问题有关的 用于实验动物使用的科学和福利，例如用于微生物学系统 功效和安全研究：关于芯片机器人器官技术进步的研讨会 动物;第四R：研究中使用的非人类灵长类动物的重新归因和退休；这 伦理和异种移植中遗传修饰的使用；和实验室动物的使用和 一个健康范式。讲习班为1）宣传与对话提供了机会 所有对实验动物在研究中使用兴趣的社区； 2）分享 尖端的科学信息； 3）对主题和 确定可能的后续活动，以提高生物医学研究的质量和 实验室动物福利。 基于动物的研究是临床前研究与开发的基本组成部分 以及对药物，生物制剂和医疗设备的概念概念研究。确保最高 这些研究的质量在维持适当的护理和使用所使用的动物的同时取决于 在研究，科学和 兽医医疗社区。因此，圆桌会议及其讲习班的目的是 与FDA的任务一致：“……通过确保安全保护公共卫生， 人类和兽医药物，生物产品，医疗设备的功效和安全性 国家的粮食供应，化妆品和发射辐射的产品”。