Alcohol and Tobacco Use and Desistance Among Asian Americans: A Lifecourse Examination of Critical Periods and Subgroup Disparities

亚裔美国人的酒精和烟草使用和戒烟：关键时期和亚群体差异的生命历程检查

• 批准号: 10187468
• 负责人: Christina Tam
• 金额: $ 19.04万
• 依托单位: PUBLIC HEALTH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-10 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10187468
• 关键词: Abstinence; Acculturation; Address; Adolescence; Adolescent; Adult; Affect; Age; Alcohol consumption; Alcohols; Applications Grants; Asian Americans; Buffers; Chinese People; Communities; Data Analyses; Development; Discrimination; Elements; Epidemiology; Ethnic Origin; Ethnic group; Family; Filipino; Future; Gender; Goals; Health; Heavy Drinking; Heterogeneity; Hispanics; Individual; Intervention; Investigation; Japanese Population; Knowledge; Koreans; Longitudinal Studies; Longitudinal trends; Mediating; Mediation; Mental Depression; Mental Health; Mentorship; Methodology; Modeling; NIH Program Announcements; National Institute on Alcohol Abuse and Alcoholism; Neighborhoods; Not Hispanic or Latino; Parents; Pathway interactions; Pattern; Population; Prevention; Research; Risk; Risk Factors; Sampling; Science; Smoking; Social Development; Social Environment; Strategic Planning; Subgroup; Time; Tobacco; Tobacco use; Translating; United States National Institutes of Health; Variant; alcohol abstinence; alcohol research; base; behavior influence; community engagement; critical period; density; design; emerging adulthood; expectation; experience; health disparity; high risk; high risk drinking; innovation; knowledge base; mortality; novel; preventive intervention; protective factors; racial and ethnic; resilience; secondary analysis; social culture; therapy development; tobacco abstinence; trend; young adult

This grant application responds to the program announcement for studies of Epidemiology and Prevention in Alcohol Research (PA-18-391) calling for exploratory and developmental research issued by the National Institute on Alcohol Abuse and Alcoholism. The application proposes a secondary analysis of data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine when and why Asian Americans engage in heavy alcohol and tobacco use and co-use across the lifecourse (from ages 12-43). In addition to exploring patterns of alcohol and tobacco co-use, we will extend the investigation of alcohol and tobacco use into adulthood with a focus on risk and resiliency factors relevant to the Asian American experience. First, the study will provide descriptions of longitudinal trends of elevated and sustained alcohol and tobacco use and co-use from adolescence to adulthood. Then, we will identify risk and resiliency predictors at multiple levels (i.e., individual, family, interpersonal, and neighborhood) for Asian Americans that are associated with sustained alcohol and tobacco use and co-use over time. We innovate by employing time-varying effect modeling to determine specific ages and developmental periods for informing preventive interventions, setting us apart from extant developmental research. The third analyses will use moderated mediation to address how contextual risks may influence behavior by ascertaining whether depression helps to explain associations of risk exposures on alcohol and tobacco use and co-use. We will examine whether protective factors at multiple levels buffer the deleterious effects of the contexts with which individuals interact. Finally, we replicate key analyses to: 1) compare Asian Americans to major US racial/ethnic groups (non-Hispanics Whites, Hispanics, and Blacks) to determine whether mechanisms are unique to this population or common across groups, and 2) assess for Asian American subgroup differences (by gender, nativity, and ethnicity) to address within-group heterogeneity in alcohol and tobacco use patterns. The objectives of this project are directly relevant to the NIH’s current strategic plan to generate knowledge for intervention development to reduce health disparities related to alcohol and tobacco. This exploratory study will inform prevention science by permitting the identification of specific contexts and mechanisms within certain developmental periods relevant to sustained alcohol and tobacco use and co-use among Asian Americans. The study will also build on prior research by extending the lifecourse examination of heavy alcohol and tobacco use into adulthood and by focusing on co-use in Asian Americans. As noted in the program announcement, this research is critical for establishing a knowledge base in developing culturally relevant preventive interventions to address use and misuse in diverse communities. Future projects will be designed to help translate the study findings into community-based, multilevel interventions for at-risk Asian Americans within specific contexts.

此赠款申请对流行病学和预防研究计划的计划公告的响应 酒精研究（PA-18-391）呼吁由国家发出的探索性和发展研究 酗酒和酒精中毒研究所。该申请提出了对数据的次要分析 国家对成人健康的纵向研究（ADD健康），以检查何时以及为什么亚洲 美国人在整个生命过程中（12-43岁）从事大量酒精和烟草的使用和共同利用。 除了探索酒精和烟草共同利用的模式外，我们还将扩展酒精的投资 和烟草在成年中使用，重点是与亚裔美国人有关的风险和弹性因素 经验。首先，该研究将提供升高和持续酒精的纵向趋势的描述， 从青春期到成年的烟草使用和共同使用。然后，我们将在 与与之相关的亚裔美国人的多个级别（即个人，家庭，人际关系和社区） 随着时间的流逝，持续的酒精和烟草使用并共用。我们通过使用时变效果无效 建模以确定特定的年龄和发展时期，以告知预防干预措施 除了额外的发展研究外。第三个分析将使用调节调解来解决如何 上下文风险可能通过确定抑郁是否有助于解释风险的关联来影响行为 关于酒精和烟草使用和共同使用的暴露。我们将检查是否在多个层面上受保护的因素 缓冲个人相互作用的上下文的有害影响。最后，我们复制关键分析 至：1）将亚裔美国人与美国主要种族/族裔（非西班牙裔白人，西班牙裔和黑人）进行比较 确定机制是该人群独有的还是跨群体共同的，以及2）评估 亚裔美国亚裔亚组差异（通过性别，耶稣降生和种族）解决集团内异质性 在酒精和烟草中使用模式。 该项目的目标与NIH目前的战略计划直接相关，以产生知识 为了减少与酒精和烟草有关的健康分布的干预开发。这项探索性研究 将通过允许在某些特定环境和机制中识别特定环境和机制来告知预防科学 与亚裔美国人中持续的酒精和烟草使用和共同使用有关的发展时期。 研究还将通过扩大重量酒精和烟草使用的生命考试来建立在先前的研究基础上 成年，并专注于亚裔美国人的共同使用。正如计划公告中指出的那样， 研究对于建立知识基础至关重要 解决潜水员社区的使用和错过。未来的项目将旨在帮助翻译研究 在特定情况下，针对高危亚裔美国人的基于社区的多层次干预措施。