Examining the long-term relationship between sleep and diet

检查睡眠和饮食之间的长期关系

• 批准号: 9911571
• 负责人: Kaitlin Storck Potts
• 金额: $ 4.55万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9911571
• 关键词: Accounting; Address; Adult; Affect; African American; Alabama; American; Area; Body mass index; Cardiovascular Diseases; Cause of Death; Characteristics; Childhood; Chronic; Cohort Studies; Communities; Complex; Data; Development; Diabetes Mellitus; Diet; Dietary intake; Disease; Drowsiness; Epidemiology; Faculty; Food; Foundations; Future; Goals; Health; Heart; Hypertension; Intervention; Knowledge; Lead; Life; Life Cycle Stages; Life Style; Link; Longitudinal Studies; Louisiana; Mentors; Methods; Mississippi; Modification; Morbidity - disease rate; Nutritional; Obesity; Outcome; Performance; Personal Satisfaction; Physical activity; Play; Population; Population Heterogeneity; Prevalence; Race; Research; Research Personnel; Research Project Grants; Research Training; Risk; Risk Factors; Role; Rural Community; Sex Differences; Sleep; Sleep Apnea Syndromes; Sleep Deprivation; Sleep Disorders; Sleep disturbances; Socioeconomic Status; Stratification; Techniques; Time; United States; United States National Institutes of Health; Weight Gain; Woman; Work; biological sex; biracial; cardiometabolic risk; cardiometabolism; cardiovascular risk factor; career; cohort; design; experience; experimental study; falls; health disparity; healthy weight; improved; lipid disorder; low socioeconomic status; meetings; men; middle age; mortality; prevent; programs; prospective; racial difference; sex; skills; sleep behavior; sleep health; sleep pattern; sleep quality; young adult

PROJECT SUMMARY/ABSTRACT Poor diet quality contributes to the excess burden of cardiometabolic diseases among U.S. adults. Short sleep and poor quality sleep are increasing and have been linked to obesity and cardiometabolic diseases. There is evidence that both diet and reduced sleep duration and quality impact African Americans and those with low socio-economic status more so than other groups, and that these differences may contribute to health disparities in cardiometabolic diseases. Specific aspects of diet have been linked to sleep outcomes in the short term and similarly, experimental studies of sleep restriction have found short sleep can lead to poor dietary choices and weight gain, demonstrating the bi-directionality of the diet and sleep relationship in the near term. However, the inter-relationship between diet and sleep is complex and has rarely been studied in the long-term nor with aspects of sleep beyond duration including quality, regularity, disturbance, and sleepiness. Therefor, this study will address this knowledge gap by examining the long-term relationships between diet and sleep in the Bogalusa Heart Study cohort of 1250 men and women from a biracial community in Louisiana that have been prospectively followed for over 40 years, since childhood. The first aim of the research is to prospectively examine the effect of multiple aspects of sleep (e.g. duration, quality, sleepiness) on dietary intake in midlife among the Bogalusa Heart Study cohort. The second aim of the research is to prospectively examine the effect of dietary intake in young adulthood on long-term sleep outcomes later in life including sleep duration, quality, regularity, disturbance, and sleepiness accounting for body mass index, risk for sleep disordered breathing, and physical activity. The third aim is to determine if differences by race, biologic sex, and socioeconomic status exist in the relationships between diet and sleep over the life course. The long-term goal in pursuing this research project and training plan is to produce an independent investigator in nutritional and lifestyle epidemiology, well prepared to pursue a research career that alleviates the burden of disparity in obesity and obesity-related morbidity and mortality for people in the Gulf South Region of the United States. This will be achieved by meeting the overall objective of this project, implementing a tailored, individualized, mentored research training experience that contributes to closing a long-standing knowledge gap in the long-term relationship between diet and sleep. The impact of this work will be to produce a future leader in nutritional and lifestyle epidemiology. The knowledge gained will allow for the development of appropriately timed and targeted intervention opportunities to maintain healthy weight and sleep patterns that prevent chronic cardiometabolic diseases among diverse populations in the U.S. while reducing health disparities. The Bogalusa Heart Study cohort is a unique and ideal setting in which to perform this research.

项目摘要/摘要 饮食质量差会导致美国成年人中心脏代谢疾病的多余负担。睡眠短 质量不佳的睡眠正在增加，并且与肥胖和心脏代谢性疾病有关。有 饮食和降低睡眠持续时间和质量都会影响非洲裔美国人和低饮食的证据 社会经济地位比其他群体更重要，并且这些差异可能有助于健康 心脏代谢疾病的差异。饮食的特定方面与睡眠结局有关 短期，同样，睡眠限制的实验研究发现睡眠短会导致较差 饮食选择和体重增加，证明了饮食和睡眠关系的双向 近期。但是，饮食和睡眠之间的相互关系很复杂，很少在 长期或与持续时间的睡眠方面的各个方面，包括质量，规律性，干扰和 嗜睡。因此，这项研究将通过检查长期关系来解决这一知识差距 在饮食和睡眠之间，在Bogalusa心脏研究队列中，由1250名男性和女性来自混血儿社区 在路易斯安那州，自童年以来一直在40多年来一直遵循。第一个目的 研究是为了前瞻性地检查睡眠多个方面的影响（例如持续时间，质量，嗜睡） 关于Bogalusa心脏研究队列中中年的饮食摄入量。这项研究的第二个目的是 前瞻性地检查成年饮食摄入量对以后长期睡眠结果的影响 包括睡眠持续时间，质量，规律性，干扰和嗜睡，占体重指数，风险 用于睡眠不足的呼吸和体育锻炼。第三个目的是确定是否按种族差异， 生物学性别和社会经济状况存在于生活过程中饮食与睡眠之间的关系中。 追求该研究项目和培训计划的长期目标是生产独立的研究者 在营养和生活方式流行病学方面，准备从事的研究职业充分减轻 肥胖和肥胖相关的发病率和死亡率的差异和死亡率 美国。这将通过满足该项目的总体目标，实施量身定制的， 个性化的指导研究培训经验，有助于结束长期知识 饮食与睡眠之间长期关系的差距。这项工作的影响将是产生未来 营养和生活方式流行病学领域的领导者。获得的知识将允许发展 适当的定时和有针对性的干预机会，以维持健康的体重和睡眠方式 在美国降低健康状况的同时，防止慢性心脏代谢疾病 差异。 Bogalusa心脏研究队列是进行这项研究的独特而理想的环境。