Physiological mechanisms of action relating to immediate and long-term therapeutic horseback riding intervention effects in a psychiatric population of youth with autism spectrum disorder
与自闭症谱系障碍青年精神病人群的即时和长期治疗性骑马干预效果相关的生理作用机制
基本信息
- 批准号:9901890
- 负责人:
- 金额:$ 58.53万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-01-10 至 2024-12-31
- 项目状态:已结题
- 来源:
- 关键词:AccreditationAddressAffectAgeAmbulatory Care FacilitiesAnimalsAnxietyArousalBehaviorBiologicalCardiovascular systemCaregiversClinicalColoradoCommunitiesControl GroupsDataData CollectionDoseEquus caballusFamilyFutureGoalsHeart RateHospitalizationHumanHybridsHydrocortisoneHyperactive behaviorImpairmentIndividualInternationalInterventionInvestigationLifeMaintenanceMeasurableMeasuresMediatingMediator of activation proteinMental DepressionMental HealthMental disordersOutcomeOutcome MeasureParticipantPatternPeripheralPhasePhysiologicalPopulationPrevalencePsychiatric DiagnosisPsychiatric HospitalsPsychiatric therapeutic procedurePsychophysiologyPublic HealthQuality of lifeRandomizedRandomized Controlled TrialsResearchResearch PersonnelSalivarySiteSourceStressStructureSubgroupTarget PopulationsTestingTherapeuticTherapeutic EffectWaiting ListsYouthalternative treatmentautism spectrum disordercomparison interventioncostdisabilityemotion dysregulationemotion regulationexperiencefollow-upgroup interventionhealth care service utilizationheart rate variabilityimprovedinterestintervention effectinventionpost interventionprogramsrecruitresponseskillssocialsocial cognitionsocial communicationstudy populationtherapy outcome
项目摘要
Project Summary/Abstract
Autism Spectrum Disorder (ASD) is a critical public health concern, given its negative quality of life
impacts, increasing prevalence rates, and high health care utilization costs. Two-thirds of the ASD population
have co-occurring psychiatric disorders. These individuals require intensive interventions to address
psychiatrically related aberrant behaviors (e.g., irritability and hyperactivity), which are the source of much of
the disability and cost for this population. The goal of this project is to assess physiological mechanisms
underlying Therapeutic Horseback Riding’s (THR) previously observed significant positive effects on
ASD youth, particularly those with co-occurring psychiatric disorders, and to further evaluate
durability, dose, and sub-population effects of the intervention. Aim 1: Test the hypothesis that
physiological response patterns of salivary cortisol, cardiovascular, and electrodermal activity account for our
previously observed significant outcomes (i.e., reduced irritability and hyperactivity, and improved social and
communication), and additional outcomes (emotion regulation and caregiver quality of life), in youth ages 6-16
yrs. with ASD and co-occurring psychiatric diagnoses randomized to a 10-week manualized THR intervention
compared to a no-horse Barn Activity (BA) control. Our preliminary findings suggest the psychiatrically
challenged ASD majority may be more likely to benefit from THR, particularly if outcomes are mediated by
physiological arousal. Aim 2: Evaluate the durability of Aim 1 outcomes in the THR group compared to the BA
control group six-months after the intervention period, given our preliminary evidence for maintenance of initial
outcome gains in a six-month follow-up. Aim 3: Explore dose and sub-population effects of THR and BA
interventions by comparing effect size differences in THR and BA groups to a: (1) 10-week wait-list control
group; (2) Hybrid intervention group (five weeks BA followed by five weeks THR); and (3) subsample of the
THR study population randomized following psychiatric hospitalization.
Our preliminary results, obtained at both PATH international premiere accredited riding centers proposed in
the current application demonstrate that peripheral physiological arousal data collection is feasible with ASD
youth while engaged in THR. We have also partially replicated our previous results and demonstrated that
cortisol is a viable target mediator of THR effects on aberrant behaviors in ASD youth that merits further
investigation. Our proposal has the potential to advance the field of human-animal interaction (HAI), specifically
THR, for individuals with ASD and co-occurring psychiatric disorders. It also stands to guide future researchers
interested in better understanding the physiological mechanisms associated with HAI. Our long-range goal is
to empirically establish THR as an ecologically valid, transdiagnostic intervention that targets underlying
psychophysiological arousal states in youth with a variety of mental health issues, facilitating acquisition and
long-term maintenance of critical life skills that enhance quality of life for individuals and their caregivers.
项目概要/摘要
自闭症谱系障碍 (ASD) 因其负面的生活质量而成为一个重要的公共卫生问题
影响、患病率上升以及高昂的医疗保健使用成本。 三分之二的 ASD 人口。
这些人同时患有精神疾病,需要加强干预来解决。
与精神相关的异常行为(例如易怒和多动),这是许多问题的根源
该项目的目标是评估该人群的残疾和费用。
潜在的治疗性骑马 (THR) 之前观察到对
ASD 青少年,特别是那些同时患有精神疾病的青少年,并进一步评估
干预措施的持久性、剂量和亚群效应 目标 1:检验以下假设。
唾液皮质醇、心血管和皮肤电活动的生理反应模式解释了我们的
先前观察到的显着结果(即减少烦躁和多动,并改善社交和
沟通),以及 6-16 岁青少年的其他结果(情绪调节和照顾者的生活质量)
患有自闭症谱系障碍 (ASD) 和同时发生的精神病诊断,随机接受为期 10 周的手动 THR 干预
与无马厩活动(BA)对照相比,我们的初步研究结果表明,从精神病学角度来看。
大多数患有自闭症谱系障碍的人可能更有可能从 THR 中受益,特别是如果结果是由
目标 2:评估 THR 组与 BA 组中目标 1 结果的持久性。
鉴于我们维持初始水平的初步证据,对照组在干预期后六个月
六个月随访中的结果增益 目标 3:探索 THR 和 BA 的剂量和亚群效应。
通过比较 THR 和 BA 组的效应大小差异来进行干预:(1) 10 周等待名单对照
组;(2) 混合干预组(五周 BA,随后五周 THR);以及 (3) 子样本
THR 研究人群在精神病院住院后随机分组。
我们在 PATH 国际首屈一指的骑行中心获得的初步结果
当前的应用表明,利用 ASD 收集外周生理唤醒数据是可行的
我们还部分复制了我们之前的结果并证明了这一点。
皮质醇是 THR 对 ASD 青少年异常行为影响的可行目标调节因子,值得进一步研究
我们的研究有可能推动人与动物相互作用(HAI)领域的发展,特别是。
THR,对于患有自闭症谱系障碍和并发精神疾病的个体来说,它也可以指导未来的研究人员。
有兴趣更好地了解与 HAI 相关的生理机制。我们的长期目标是。
凭经验将 THR 确立为一种生态有效的跨诊断干预措施,针对潜在的
患有各种心理健康问题的青少年的心理生理唤醒状态,有助于获得和
长期维持关键的生活技能,提高个人及其护理人员的生活质量。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('ROBIN L GABRIELS', 18)}}的其他基金
Physiological mechanisms of action relating to immediate and long-term therapeutic horseback riding intervention effects in a psychiatric population of youth with autism spectrum disorder
与自闭症谱系障碍青年精神病人群的即时和长期治疗性骑马干预效果相关的生理作用机制
- 批准号:
10083751 - 财政年份:2020
- 资助金额:
$ 58.53万 - 项目类别:
Physiological mechanisms of action relating to immediate and long-term therapeutic horseback riding intervention effects in a psychiatric population of youth with autism spectrum disorder
与自闭症谱系障碍青年精神病人群的即时和长期治疗性骑马干预效果相关的生理作用机制
- 批准号:
10328514 - 财政年份:2020
- 资助金额:
$ 58.53万 - 项目类别:
Physiological mechanisms of action relating to immediate and long-term therapeutic horseback riding intervention effects in a psychiatric population of youth with autism spectrum disorder
与自闭症谱系障碍青年精神病人群的即时和长期治疗性骑马干预效果相关的生理作用机制
- 批准号:
10557844 - 财政年份:2020
- 资助金额:
$ 58.53万 - 项目类别:
Effects of Therapeutic Horseback Riding on Children and Adolescents with Autism S
骑马治疗对自闭症儿童和青少年的影响
- 批准号:
7993477 - 财政年份:2010
- 资助金额:
$ 58.53万 - 项目类别:
Effects of Therapeutic Horseback Riding on Children and Adolescents with Autism S
骑马治疗对自闭症儿童和青少年的影响
- 批准号:
8488485 - 财政年份:2010
- 资助金额:
$ 58.53万 - 项目类别:
Effects of Therapeutic Horseback Riding on Children and Adolescents with Autism S
骑马治疗对自闭症儿童和青少年的影响
- 批准号:
8290415 - 财政年份:2010
- 资助金额:
$ 58.53万 - 项目类别:
Effects of Therapeutic Horseback Riding on Children and Adolescents with Autism S
骑马治疗对自闭症儿童和青少年的影响
- 批准号:
8142971 - 财政年份:2010
- 资助金额:
$ 58.53万 - 项目类别:
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