Developmental Research Program

发展研究计划

• 批准号: 9766216
• 负责人: DAVID F STERN
• 金额: $ 7.48万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9766216
• 关键词: Area; Clinical; Clinical Management; Collaborations; Communities; Coupled; Cutaneous; Cutaneous T-cell lymphoma; Dermatology; Development; Diagnosis; Direct Costs; Ensure; Evaluation; Faculty; Funding; Funding Opportunities; Future; Goals; Grant; Human; Institution; Investigation; Leadership; Pilot Projects; Play; Prevention; Privatization; Program Research Project Grants; Recommendation; Research; Research Activity; Research Personnel; Research Project Grants; Resource Development; Role; Science; Skin Cancer; Source; Translational Research; Translations; United States National Institutes of Health; Yale Cancer Center; anticancer research; base; cancer risk; innovation; inter-institutional; interest; keratoacanthoma; meetings; melanoma; multidisciplinary; novel; oncology; outcome forecast; programs; research and development; success; technology development

DEVELOPMENTAL RESEARCH PROGRAM: PROJECT SUMMARY The primary goal of the Yale SPORE in Skin Cancer Developmental Research Program (DRP) is to provide limited support (maximum of $50,000/year, typically for no more than two years) for a broad spectrum of innovative skin cancer pilot projects (involving research, resources, and technology development applicable to human skin cancer risk, prevention, diagnosis, prognosis, or treatment). These pilot projects must have promising translational research potential, with anticipation that they can eventually develop into, or be incorporated into, full projects with an unequivocal clinical translational component. Such projects could either be developed into independent external funding at a scope and scale equivalent to a NIH R01 grant, or alternatively augment or replace a Project in future cycles of the Yale SPORE in Skin Cancer. A total of at least $230,000/year will be used for Developmental Research Projects ($56,262 in direct costs and at least $173,738 in institutional matching funds guaranteed by the Yale Cancer Center and the Department of Dermatology). These funds will make it possible to support up to five DRP projects annually, ranging from $30,000 to $50,000 each. A second goal of this DRP is broaden the collective of Yale investigators who are actively engaged in research related to human cutaneous oncology. During its second five-year funding period, the YSPORE DRP has funded 22 different projects (20 related to melanoma, one to cutaneous T cell lymphoma, one to keratoacanthoma) involving 28 different investigators from 15 different departments and sections at Yale, and two outside institutions. Six of the projects involved multiple PIs and encompassed multidisciplinary activities.

发展研究计划：项目摘要 皮肤癌发展研究计划（DRP）中耶鲁孢子的主要目标是提供 有限的支持（最高$ 50,000/年，通常不超过两年） 创新的皮肤癌试点项目（涉及适用于研究，资源和技术开发 人皮肤癌的风险，预防，诊断，预后或治疗）。这些试点项目必须有 有希望的转化研究潜力，并期待他们最终可以发展成或 纳入具有明确的临床翻译成分的完整项目。这样的项目可以 在范围和规模上被发展为独立的外部资金，等同于NIH R01赠款或 或者，在皮肤癌中耶鲁孢子的未来周期中增加或替换项目。至少至少 $ 230,000/年将用于发展研究项目（直接成本为56,262美元，至少 耶鲁癌症中心和部门保证的机构匹配资金$ 173,738 皮肤科）。这些资金将使每年最多支持五个DRP项目成为可能 每个$ 30,000至$ 50,000。此DRP的第二个目标是扩大耶鲁大学调查员的集体 积极从事与人皮肤肿瘤学有关的研究。在其第二个五年的资金期间， Yspore DRP资助了22个不同的项目（20个与黑色素瘤有关，一种与皮肤T细胞有关 淋巴瘤，一种致玉蛋白原瘤），涉及来自15个不同部门的28个不同研究人员， 耶鲁大学的部分和两个外部机构。六个项目涉及多个PI并包含 多学科活动。