Wave-Cam: A novel micro-radar imaging array for non-rigid motion estimation in hybrid medical imaging

Wave-Cam：一种新型微雷达成像阵列，用于混合医学成像中的非刚性运动估计

基本信息

批准号：
9895557
负责人：
Clifford Lindsay
金额：
$ 28.06万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-21 至 2022-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9895557
关键词：
3-Dimensional Accounting Address Agreement Anatomy Anterior Asses Back Beds Body Surface Cessation of life Characteristics Clinical Clothing Confidence Intervals Data Detection Devices Diagnosis Disease Electromagnetic Energy Electromagnetics Electronics Financial compensation Gender Goals Heart Diseases Human Human Volunteers Hybrids Image Industry Inferior Injections Life Malignant Neoplasms Measures Medical Imaging Medical center Methods Military Personnel Modality Monitor Motion Multimodal Imaging Myocardial perfusion Noise Operative Surgical Procedures Patient imaging Patients Performance Perfusion Phase Positron-Emission Tomography Prevalence Process Radar Radiation Resolution Sampling Security Semiconductors Surface System Technology Testing Therapeutic Thick Time Uncertainty Universities Validation Vermont attenuation base clinical imaging cost digital imaging potential imaging study imaging system interest medical schools metal oxide millimeter miniaturize multimodality novel perfusion imaging prevent prototype radiotracer reconstruction respiratory screening single photon emission computed tomography software development volunteer

项目摘要

Abstract During medical imaging, patient motion is unavoidable and can result in significant image degradation. Heart disease and cancer account for almost half of all deaths in the U.S. and considering the prevalence of imaging for diagnosis, therapeutic monitoring, and surgical planning for these diseases, degraded images due to patient motion can have significant implications. Furthermore, in multi-modal imaging the potential for misalignment from patient motion between sequential acquisitions distorts intermodality alignment decreasing the utility of imaging. Existing strategies for motion correction are classified as either: 1) data-driven by utilizing imaging data or 2) use of a device external to the imaging system(s) that estimates motion of internal volumes of interest (VOI) by tracking the motion of a surrogate, such as the patient’s body surface. External motion tracking (EMT) is a popular alternative to data-driven approaches as it is unaffected by modality characteristics, such noise levels and radiotracer distribution and can be used for tracking in multi-modal systems. The majority of EMT cameras actively illuminate patients with visible or near infrared electromagnetic radiation that is reflected back by patient garments. The opaqueness of garments to this type of radiation prevents tracking of the patient’s actual body surface, thereby adding a level of uncertainty when estimating the motion. Thus, if the patient is clothed, then current EMTs only track garments or markers which are themselves acting as surrogates to the patient’s body surface, which is tantamount to tracking a surrogate to another surrogate to the VOI. Our premise is that patient garments pose an unsurmountable barrier to EMTs that limit their motion tracking and compensation performance in clinical imaging. As such, we propose to develop a novel EMT that utilizes a part of the electromagnetic spectrum for which clothing is transparent, thus overcoming this limitation, and in turn transforming the way motion tracking is performed in clinical settings.

抽象的在医学成像过程中，患者运动不可避免，并且可能导致显着的图像降解。心疾病和癌症几乎占美国所有死亡的一半，并考虑了成像的流行对于这些疾病的诊断，热监测和外科手术计划，患者会降解图像运动可以具有重大影响。此外，在多模式成像中，从顺序采集之间的患者运动扭曲了模式间比对减少了成像的效用。现有的运动校正策略归类为：1）使用成像数据或2）使用数据驱动成像系统外部设备的设备，该设备通过跟踪替代物的运动，例如患者的身体表面。外部运动跟踪（EMT）是数据驱动方法的流行替代方案，因为它不受模态特征的影响，这种噪声水平和放射性示意剂分布，可用于在多模式系统中进行跟踪。大多数EMT摄像机积极阐明患者反映的可见或接近红外电子辐射的患者服装。服装对这种辐射的不透明性阻止了患者实际身体的跟踪表面，从而在估计运动时会增加一定程度的不确定性。那，如果病人穿衣服，那就当前的EMT仅跟踪服装或标记本身就是对患者身体的代孕表面，这与跟踪替代物的替代替代物的差异。我们的前提是病人服装对EMT构成了限制其运动跟踪和赔偿的不可观的障碍临床成像的性能。因此，我们建议开发一种利用一部分的小说EMT 服装是透明的电磁频谱，从而克服了这种限制，然后又改变运动跟踪的方式在临床环境中进行。