Gulf Regional Area Stroke Program and Oklahoma

海湾地区中风计划和俄克拉荷马州

基本信息

批准号：
9762239
负责人：
Sean I Savitz
金额：
$ 30.65万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9762239
关键词：
Adult Alabama Anticoagulants Area Arteries Attention Brain hemorrhage Caring Cerebral hemisphere hemorrhage Clinical Research Clinical Trials Coagulation Process Collaborations Communities Conduct Clinical Trials Development Devices Education Enrollment Environment Lead Leadership Link Louisiana Minority Minority Recruitment Mississippi National Institute of Neurological Disorders and Stroke Oklahoma Oral Patients Phase Philosophy Randomized Clinical Trials Recording of previous events Recovery Rehabilitation therapy Reperfusion Therapy Research Retrieval Scientist Site Stroke Stroke prevention Testing Texas Therapeutic Training United States Universities Woman acute stroke austin bench to bedside career clinical research site design disability ethnic diversity improved metropolitan multidisciplinary novel novel marker patient population pediatric patients post stroke pre-clinical prevent programs randomized trial stroke recovery stroke therapy stroke trials working group

项目摘要

Our center for 30 years has been a leader in clinical trials testing new treatments for stroke and brain hemorrhage. In this application, we aim to continue serving as a leading regional coordinating center (RCC) in StrokeNet and have assembled a well-organized group of connected clinical sites linked by a history of productive collaboration and led by a multidisciplinary and ethnically diverse team. In Specific Aim 1, we intend to continue leading a RCC consisting of multidisciplinary teams to conduct clinical trials testing novel stroke therapies in acute stroke, stroke prevention, and stroke recovery. The UTHealth RCC will conduct clinical trials within a network of inter-connected sites throughout Texas, Oklahoma, and Louisiana, involving both adult and pediatric patients with attention to the recruitment of minorities and women. In specific Aim 2, we will continue to provide expertise and leadership for the design of novel trials and propose trials testing new stroke therapies in acute stroke, stroke prevention, and stroke recovery. We will also provide translational expertise for the development of new stroke therapies from bench to bedside and for the development and testing of novel biomarkers. In specific Aim 3, we will continue to provide a career enhancement program within our network for clinician-scientists with high potential for independent research careers in stroke.

30 年来，我们的中心一直是中风和脑部新疗法临床试验的领导者出血。在此应用中，我们的目标是继续充当领先的区域协调中心 (RCC) 在 StrokeNet 中，并组装了一组组织良好的相互连接的临床站点，通过以下方式链接有着富有成效的合作历史，由多学科、多种族的团队领导。在具体目标 1，我们打算继续领导一个由多学科团队组成的 RCC 开展测试新型中风疗法在急性中风、中风预防和中风恢复方面的临床试验。 UTHealth RCC 将在遍布各地的互连站点网络内进行临床试验德克萨斯州、俄克拉荷马州和路易斯安那州，涉及成人和儿童患者，并关注招募少数民族和妇女。在具体目标 2 中，我们将继续提供专业知识和领导新试验的设计，并提出测试急性中风新疗法的试验中风、中风预防和中风康复。我们还将为以下项目提供翻译专业知识开发从实验室到临床的新中风疗法，并开发和测试新颖的生物标志物。在具体目标 3 中，我们将继续提供职业提升计划在我们的网络中，为具有独立研究职业潜力的临床医生科学家提供服务中风。