Modifiable Behavior & Dietary Predictors of Overweight in Children with ASD

可修改的行为

• 批准号: 8637572
• 负责人: Susana R Patton
• 金额: $ 23.95万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8637572
• 关键词: Adult; Affect; Age; Arthritis; Atherosclerosis; Autistic Disorder; Behavior; Behavioral; Biochemical Markers; Bite; Blood Glucose; Blood Pressure; Body mass index; Characteristics; Child; Child Behavior; Childhood; Chronic; Clinical; Cognitive; Colorectal Cancer; Consumption; Coronary heart disease; Data; Development; Diagnosis; Diet; Dyslipidemias; Eating; Epidemic; Ethnography; Evidence based intervention; Exercise; Face; Family; Fatty acid glycerol esters; Food; Food Selections; Fruit or Vegetable; Future; Goals; Health; High Prevalence; Home environment; Hypertension; Impairment; Insulin; Insulin Resistance; Intervention; Knowledge; Lead; Life; Link; Lipids; Methodology; Methods; Mission; Motor Skills; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Overweight; Parents; Population; Preventive Intervention; Process; Public Health; Reporting; Research; Research Priority; Risk; Running; Stress; Time; United States National Institutes of Health; Vulnerable Populations; Weight; Weight maintenance regimen; Youth; autism spectrum disorder; base; burden of illness; cost; dietary control; evidence base; experience; feeding; high risk; hypertensive heart disease; improved; innovation; longitudinal design; medical specialties; patient population; prevent; programs; public health relevance; therapy development; young adult

DESCRIPTION (provided by applicant): Pediatric overweight has reached epidemic levels and, at 36%, children with autism spectrum disorder (ASD) have a higher rate of overweight than typically developing children. Pediatric overweight is a major health problem because it is linked to childhood onset of dyslipidemia, hypertension, high blood sugar, and Type 2 Diabetes. Also youths who grow up overweight, will as adults, face higher rates of hypertension, heart disease, atherosclerosis, colorectal cancer, arthritis, and chronic overweight. Yet, despite a pressing need for effective prevention and intervention efforts for overweight in children with ASD, we are significantly hampered in developing appropriate programs because we lack empirical data on potentially important dietary and behavioral factors. Children with ASD have unique impairments and behaviors that can complicate weight management, including difficulty with motor skills, cognitive difficulties, problematic mealtime behaviors and greater food refusal and selectivity than typically developing children, which make it highly unlikely that available weight management interventions for typically developing children will generalize to them. Therefore, there is a critical need for research examining factors related to overweight in children with ASD specifically. The long-term goal of our research is to identify evidence-based methods for preventing and treating overweight in children with ASD. The goal of the current project is to identify parent and child mealtime behavior and diet characteristics that are related to child weight status as a basis for future research to develop a suitable weight management program for children with ASD. The current study aims are: 1) identify child and parent mealtime behaviors associated with present and future weight in young children with ASD and 2) assess if diet variables are related to present and future child weight. This project is significant because t is expected to provide much needed information on factors related to overweight in children with ASD, which can be used to develop and refine weight management programs for children with ASD, an understudied population for weight management. The project is innovative because of its proposed home-based ethnographic methodology and longitudinal design, which both represent a substantial departure from existing studies in children with ASD and offer the opportunity to collect data necessary for intervention development. We expect our approach will greatly expand the body of knowledge for this under-studied but vulnerable population of children and will lay the groundwork for the development and dissemination of tailored weight management programs, two research goals which are in line with priorities for the NIH Autism Interagency Coordinating Center and the Autism Treatment Networks. Given the large number of children with ASD and the high prevalence of overweight in this population, the development and dissemination of tailored weight management programs for these children is expected to lead to improved health and functioning for a large number of children.

描述（由申请人提供）：儿童超重已达到流行水平，患有自闭症谱系障碍 (ASD) 的儿童超重率为 36%，高于正常发育儿童的超重率。儿童超重是一个主要的健康问题，因为它与儿童期血脂异常、高血压、高血糖和 2 型糖尿病的发病有关。此外，超重的青少年在成年后，患高血压、心脏病、动脉粥样硬化、结直肠癌、关节炎和慢性超重的几率也会更高。然而，尽管迫切需要对自闭症谱系障碍儿童超重进行有效的预防和干预工作，但我们在制定适当的计划方面受到严重阻碍，因为我们缺乏有关潜在重要饮食和行为因素的经验数据。患有自闭症谱系障碍 (ASD) 的儿童具有独特的障碍和行为，可能会使体重管理复杂化，包括运动技能困难、认知困难、有问题的进餐行为以及比正常发育儿童更严重的拒食和选择性，这使得对正常发育儿童提供体重管理干预措施的可能性极小。孩子们会对他们进行概括。因此，迫切需要专门研究与自闭症儿童超重相关的因素。我们研究的长期目标是找到预防和治疗自闭症儿童超重的循证方法。当前项目的目标是确定父母和孩子相关的进餐行为和饮食特征 以儿童体重状况作为未来研究的基础，为患有自闭症谱系障碍的儿童制定合适的体重管理计划。目前的研究目标是：1）确定儿童和家长的进餐行为与自闭症谱系障碍幼儿当前和未来的体重相关；2）评估饮食变量是否与当前和未来的儿童体重相关。该项目意义重大，因为预计将提供有关自闭症谱系障碍儿童超重相关因素的急需信息，这些信息可用于为自闭症谱系障碍儿童（体重管理方面尚未得到充分研究的人群）制定和完善体重管理计划。该项目之所以具有创新性，是因为其提出的基于家庭的人种学方法和纵向设计，这两者都与自闭症儿童的现有研究有很大不同，并提供了收集干预发展所需数据的机会。我们期望我们的方法将大大扩展这一研究不足但脆弱的儿童群体的知识体系，并为定制体重管理计划的开发和传播奠定基础，这两个研究目标与 NIH 自闭症优先事项一致机构间协调中心和自闭症治疗网络。鉴于患有自闭症谱系障碍的儿童数量众多，而且该人群中超重的患病率很高，为这些儿童制定和传播量身定制的体重管理计划预计将改善大量儿童的健康和功能。