Cancer-Translational Nanotechnology Training Program (Cancer-TNT)

癌症转化纳米技术培训计划（Cancer-TNT）

• 批准号: 9321153
• 负责人: DEAN W FELSHER
• 金额: $ 37.43万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9321153
• 关键词: Malignant Neoplasms; Nanotechnology; Training Programs

 DESCRIPTION (provided by applicant): The proposed postdoctoral training program, Cancer-Translational Nanotechnology Training (Cancer-TNT) Program, is a diverse and synergistic 3-year training program bringing together 25 faculty and 9 Departments from three schools to train the next generation of interdisciplinary leaders who will pursue challenges in cancer research and clinical translation. Cancer nanotechnology is a rapidly growing field that requires close interactions of researchers from disparate fields of science, such as chemistry, materials science, cancer biology, and medicine. During the proposed 5-year cycle, we will recruit a total of 12 postdoctoral trainees to provide them with education and cross-disciplinary training to develop interdisciplinary researchers in cancer nanotechnology translation. Eight (8) trainees will complete training during the 5-year cycle. Our trainees' skill sets will bridge multiple disciplines such as chemistry, molecular biology, bioengineering, molecular imaging, nanoengineering, and clinical cancer medicine. Trainees will be able to advance cancer research, diagnosis, and management. The Molecular Imaging Program at Stanford (MIPS) from the medicine side, with the Departments of Chemistry, Materials Science and Engineering from the engineering side, will provide a solid foundation for our program. The Stanford environment also leads a productive Center for Cancer Nanotechnology Excellence (CCNE-T), an NCI Designated Comprehensive Cancer Center, an In Vivo Cellular and Molecular Imaging Center (ICMIC @ Stanford), the highly effective interdisciplinary Bio-X program, facilities for Nanofabrication and Nanocharacterization, as well as Nanoinformatics capabilities, the Canary Center for Cancer Early Detection, and a Physical Sciences Oncology Center (PSOC), in which several of our mentors have leading roles. Through these activities, we have already been successfully training the next generation of cancer nanotechnologists and we are excited by the possibility to formalize and expand training activities through the Cancer-TNT. Our program includes a diverse group of faculty mentors representing five program areas. Through this mentor group, we are able to bring together formal courses in cancer biology, cancer immunology, molecular imaging, molecular pharmacology, and gene therapy, nanomedicine, micro/nanofabrication, biochips, electrical engineering, and materials science; hands-on training activities in Nanocharacterization; and a clinical component including Stanford Oncology Clinical Lecture Series. The Cancer-TNT fellows will be recruited into a 3-year program to complete coursework and research with two complementary mentors. Trainees will prepare a mock grant proposal in their second year to help them gain experience and confidence in the grant application process. A Training Committee will oversee trainee progress, with an Advisory Committee monitoring the entire program. Stanford University, with support from the NCI, is poised to be a major training center for the rapidly growing field of cancer nanotechnology.

 描述（由应用程序提供）：拟议的博士后培训计划，癌症翻译纳米技术培训（CANCER-TNT）计划，是一项不同且协同的3年培训计划，将25名教职员工和来自三所学校的9个部门培训，培训下一代跨学科领导者，他们将在癌症研究和临床翻译中寻求挑战。癌症纳米技术是一个快速增长的领域，需要从不同科学领域的研究人员进行密切相互作用，例如化学，材料科学，癌症生物学和医学。在拟议的5年周期中，我们将招募12名博士后学员，为他们提供教育和跨学科培训，以发展癌症纳米技术翻译的跨学科研究人员。八（8）名学员将在5年周期完成培训。我们的学员的技能将桥接多个学科，例如化学，分子生物学，生物工程，分子成像，纳米工程和临床癌症医学。学员将能够推进癌症研究，诊断和管理。来自医学侧的斯坦福大学（MIPS）的分子成像计划，与工程方面的化学，材料科学和工程部门有关，将为我们的计划奠定坚实的基础。斯坦福大学的环境还领导着一个生产性癌症纳米技术卓越中心（CCNE-T），NCI指定综合癌症中心，一个体内细胞和分子成像中心（ICMIC @ stanford），高效的跨学科BIIO-X计划，是NananoFabrication和Nanano Charactional and anno Character and nanochar and anno canirational and NoNoIn and anno andarational and noano and noanoin andarational，以及检测和物理科学肿瘤学中心（PSOC），我们的几个导师扮演了领导角色。通过这些活动，我们已经成功地培训了下一代癌症纳米技术医生，我们对通过癌症TNT进行正式和扩展培训活动的可能性感到兴奋。我们的计划包括一个代表五个计划领域的教师导师的潜水员。通过这个导师小组，我们能够将癌症生物学，癌症免疫学，分子成像，分子药理学和基因治疗，纳米医学，微/纳米型，生物芯片，电气工程和材料科学的正式课程汇总在一起；纳米饰面的动手培训活动；以及包括斯坦福肿瘤学临床讲座系列的临床成分。癌症-TNT研究员将被招募为为期3年的计划，以完成两名完整的导师的课程和研究。学员将在第二年准备一项模拟赠款提案，以帮助他们获得对赠款申请流程的经验和信心。培训委员会将监督受训者的进步，并在整个计划中监视咨询委员会。斯坦福大学在NCI的支持下被毒死，成为癌症纳米技术快速增长领域的主要培训中心。