Training in Biostatistics for Heart, Lung and Blood Disease Research

心脏、肺和血液疾病研究生物统计学培训

• 批准号: 9270074
• 负责人: James Dennis Neaton
• 金额: $ 19.12万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9270074
• 关键词: Biometry; Heart Diseases; Hematological Disease; Lung diseases; Research; Training

 DESCRIPTION (provided by applicant): There is a critical shortage of biostatisticians to work on clinical and translational research teams. This proposal aims to train predoctoral students to become biostatistical scientists that will provide leadership to multidisciplinary teams in academic settings that conduct research aimed at preventing and treating heart, lung, and blood disease. The training program is innovative, rigorous, and multidisciplinary. It builds on an already strong program that provides foundational courses in statistical theory and biostatistical applications and several existing collaborations to create a Heart, Lung, and Blood Disease Clinical Trials Area of Emphasis in our PhD program. This area of emphasis will include courses in cardiac physiology, public health aspects of cardiovascular disease, advanced clinical trial design, and a journal club/seminar series that focuses on the design, analysis, and reporting of clinical trials of interventions for the prevention and treatment of heart, lung, and blood disease Each trainee with have a senior biostatistical mentor, a junior biostatistical mentor who can serve as a role model, and a senior clinical mentor with expertise in heart, lung or blood disease. We also plan to promote interactions among our trainees and young clinical researchers. Trainees will develop methods and work on applications using data from clinical trials aimed at preventing and treating heart, lung, and blood disease. They will attend statistica and medical conferences with their mentors and, in order to gain an appreciation for field work and data collection, spend 2 weeks at a clinical site participating in an ongoing clinical trial. Trainees will be supported for 3 of their 5 years in our PhD program. Support for other years will come from a heart, lung, or blood disease research project. Salary, tuition, and limited travel support is requested for 2 new predoctoral trainees in each year of the grant. Substantial institutional support for this training program has been provided by the School of Public Health and the Division of Biostatistics. This reflects the institutional commitment to multidisciplinary research in general, and the recognition of the many challenges that exist to reduce the burden of heart, lung, and blood disease in the U.S. and worldwide. There is a critical shortage of biostatisticians to provide leadership to multidisciplinary teams conducting research aimed at preventing and treating heart, lung, and blood disease. This training program addresses this shortage by establishing an area of emphasis on heart, lung, and blood disease clinical trials in an already strong PhD program that provides foundational courses in statistical theory and biostatistical applications. This innovative training program includes course work on the underlying biology and epidemiology of these diseases and mentoring from a committed faculty of biostatisticians and senior clinicians. (End of Abstract)

 描述（由应用程序提供）：生物统计学家严重短缺临床和翻译研究团队。该提案旨在培训前学生，成为生物统计学科学家，这些科学家将在学术环境中为多学科团队提供领导才能，以预防和治疗心脏，肺部和血液疾病进行研究。培训计划是创新，严格且多学科的。它建立在一个已经很强的计划的基础上，该计划提供了统计理论和生物统计应用的基础课程，以及在我们的博士学位计划中创建心脏，肺和血液疾病临床试验领域的几种现有合作。这一重点领域将包括心脏生理学，心血管疾病的公共卫生方面，高级临床试验设计以及期刊俱乐部/研讨会系列，重点介绍设计，分析和报告的临床试验，以预防和治疗心脏，肺部和血液疾病的临床临床试验，并具有高级临床临床型司法机构，可以在高级临床中扮演高级精神，培养高级精神上的精神，培养了一定的精神上的精神，培养了高级精神上的精神，该临床疾病能够为您提供高级精神上的精神效应，以便为您服务于高级临床，而培养了高级精神上的临床疾病，该临床疾病能够为您提供高级临床，并能够为您提供高级临床，并能够为您提供高级临床，并能够为您提供高级临床培训。心脏，肺或血液疾病的专业知识。我们还计划促进学员和年轻临床研究人员之间的互动。受训者将使用旨在预防和治疗心脏，肺和血液疾病的临床试验的数据开发方法并在应用方面进行工作。他们将与他们的导师一起参加统计和医疗会议，为了对现场工作和数据收集获得赞赏，在参加正在进行的临床试验的临床现场度过了2周。在我们的博士学位课程中，将为学员提供5年的支持中的3年。对其他年份的支持将来自心脏，肺或血液疾病研究项目。在赠款的每一年中，请要求2名新的托管前学员提供工资，学费和有限的旅行支持。公共卫生学院和生物统计局提供了对该培训计划的大量机构支持。这反映了一般对多学科研究的制度承诺，以及对减少美国和全球血液燃烧的许多挑战的认识。生物统计学家严重短缺，为旨在预防和治疗心脏，肺部和血液疾病的多学科团队提供领导才能。该培训计划通过在已经很强的博士学位计划中建立了对心脏，肺和血液疾病临床试验的重视领域来解决这一短缺，该试验提供了统计理论和生物统计学应用的基础课程。这项创新的培训计划包括有关这些疾病的基本生物学和流行病学的课程工作，以及来自忠实的生物统计学家和高级临床医生的心理工作。 （抽象的结尾）