Biological Underpinnings of Maternal Attachment in High Risk Populations

高危人群母性依恋的生物学基础

基本信息

批准号：
9292069
负责人：
JEANNE L ALHUSEN
金额：
$ 14.66万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-02 至 2019-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9292069
关键词：
Address Adult Affect Age Area Attenuated Award Behavior Berlin Biological Biological Process Biology Caucasians Child Child Development Child Rearing Childhood Chronic stress Collection Complex Data Analyses Development Doctor of Philosophy Early Intervention Effectiveness Emotional Family Foundations Generations Goals Health Home visitation Hormones Human Hydrocortisone Impairment Income Individual Infant Intervention Knowledge Life Low income Measures Mental Health Mentors Mentorship Mother-Child Relations Mothers Neonatal Neuropeptides Outcome Outcomes Research Oxytocin Parent-Child Relations Physiological Physiological Processes Physiology Poverty Process Regulation Research Research Training Role Sampling Secure Security Shapes Site Statistical Data Interpretation Stress Supervision Training Treatment outcome Universities Virginia Woman Work biobehavior career caregiving cognitive development community setting design early childhood effective intervention ethnic minority population high risk population hypothalamic pituitary axis improved intervention program multidisciplinary primary caregiver programs protective behavior psychologic psychosocial public health relevance racial diversity response responsible research conduct skills social therapy design urban poverty

项目摘要

DESCRIPTION (provided by applicant): This K23 application prepares the candidate, Jeanne Alhusen, PhD, for a research-intensive career leading multidisciplinary efforts to improve early childhood outcomes in children targeted by early intervention programs in community settings. Specifically, I aim to become an expert in the biological and psychological underpinnings of maternal attachment and its influence on maternal-child physiological attunement, and ultimately early childhood outcomes. Understanding these relations is critical in understanding, from a biological perspective, how secure maternal attachment may confer developmental advantages in young children living in poverty and how maternal biology can impact the effectiveness of early interventions. The overall aims of this proposal are to (a) examine the relations among maternal cortisol, oxytocin, attachment style, sensitivity, (b) examine the moderating role of maternal-child cortisol attunement on the association between maternal attachment style and maternal sensitivity and (c) examine the associations between maternal-child cortisol attunement and early childhood outcomes in 75 mother-child dyads living in urban poverty. In the short-term, the current proposal will allow me to gain the skills and expertise to conduct mentored research on the biological and psychological underpinnings of maternal attachment and their relation to maternal sensitivity, maternal-child physiological attunement, and ultimately early childhood outcomes. To accomplish this, I need to acquire a fundamentally different skill set. My training plan is explicitly designed to address gaps in my knowledge of maternal attachment and its related biological processes (i.e., cortisol, oxytocin) that may compromise early childhood outcomes. Short-term training objectives include training in 1) biological measures of attachment and stress, 2) parent-child interaction assessment, 3) advanced training in treatment outcome research and related statistical analyses and, 4) skills requisite for a successful academic career (i.e., responsible conduct of research, grantsmanship, leading interdisciplinary teams). These training goals, together with the specific aims of the research plan, will lead to an R01 application, the theme of which will be incorporating the biological underpinnings of attachment into developing interventions to improve maternal attachment which will ultimately improve caregiving quality and early childhood outcomes. Throughout the mentored award period, the candidate will work under the supervision of Dr. Gayle Page, Johns Hopkins University, and Dr. Linda Bullock, the University of Virginia, experts in biobehavioral and maternal mental health research, respectively. The candidate will also receive mentorship from three senior consultants (Dr. Lane Strathearn, Dr. Lisa Berlin, Dr. Sharon Ghazarian) with complementary areas of expertise, carefully selected to address each of her training goals.

描述（由应用程序提供）：本k23申请为候选人珍妮·阿尔胡森（Jeanne Alhusen）博士做好准备，为研究密集型职业领先的多学科努力，以改善社区环境中早期干预计划针对的儿童的幼儿幼儿结局。具体而言，我的目标是成为生物依恋的生物学和心理基础的专家，及其对母子生理调整的影响，并最终是幼儿期的成果。从生物学的角度来看，理解这些关系对于理解至关重要，安全的孕产妇依恋如何会在贫困中的幼儿中会有发展优势，以及孕产妇生物学如何影响早期干预措施的有效性。该提案的总体目的是（a）检查孕妇皮质醇，催产素，依恋样式，敏感性，（b）研究母亲儿童的调整对孕产妇依恋风格和母体植物敏感性和（c）在孕产妇的植物效应和（c）对孕产妇的相关性之间的关联的调节作用，并研究孕产妇的早期植物的关联。城市贫困。在短期内，当前的提案将使我能够获得有关孕产妇依恋的生物学和心理基础的技能和专业知识，及其与产妇敏感性，母亲孩子的生理调整以及最终的早期儿童成果的关系。为此，我需要获得根本不同的技能。我的培训计划是明确设计的，目的是解决我对质地依恋及其相关生物过程（即皮质醇，催产素）的差距，这些过程可能会损害幼儿的早期结果。短期培训对象包括1）培训1）依恋和压力的生物学测量，2）亲子互动评估，3）治疗结果研究和相关统计分析的高级培训，以及4）成功的学术职业所需的技能（即负责任的研究，助学士，助学士，领导跨学科团队）。 These training goals, together with the specific aims of the research plan, will lead to an R01 application, the theme of which will be incorporating the biologic underpinnings of attachment into developing interventions to improve maternal attachment which Throughout the mended award period, the candidate will work under the supervision of Dr. Gayle Page, Johns Hopkins University, and Dr. Linda Bullock, the University of Virginia, experts in biobehavioral and maternal mental health research, 分别。候选人还将从三位高级顾问（Lane Strathearn博士，莱萨·柏林博士，莎朗·加扎尔博士）的心态中获得完善的专业领域，并精心挑选以解决她的每个培训目标。