SDMC - IMPAACT Leadership Group

SDMC - IMPAACT 领导小组

基本信息

批准号：
9187412
负责人：
David Eric Shapiro
金额：
$ 978.04万
依托单位：
HARVARD SCHOOL OF PUBLIC HEALTH
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-06-29 至 2020-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9187412
关键词：
AIDS clinical trial group AIDS prevention Acquired Immunodeficiency Syndrome Address Adolescent Anti-Retroviral Agents Area Behavior Therapy Biological Assay California Child Childhood Clinical Clinical Trials Clinical Trials Network Collaborations Communication Comorbidity Conduct Clinical Trials Consultations Data Development Diagnosis Doctor of Philosophy Dose Drug Interactions Drug Kinetics Ensure Epidemiologist Family health status Formulation Foundations HIV HIV Infections HIV prevention trials network HIV-infected adolescents Hepatitis Hepatitis B Hepatitis C Infant Infection International International Maternal Pediatric Adolescent AIDS Clinical Trials Intervention Laboratories Lead Leadership Licensing Methods Mission Morbidity - disease rate National Institute of Allergy and Infectious Disease Perinatal Pharmaceutical Preparations Pharmacology Population Postpartum Women Pregnant Women Prevention Principal Investigator Protocols documentation Public Health Schools Research Research Design Research Infrastructure Research Personnel Research Priority Safety Science Sexual Partners Site System Technology Testing Therapeutic Intervention Training Tuberculosis United States Universities Vaccines Vertical Disease Transmission Work antiretroviral therapy base co-infection data management design disorder prevention experience flexibility frontier high standard immunogenicity innovation international center mortality novel novel drug combination novel strategies novel therapeutics operation organizational structure pediatric AIDS pregnant prevent transmission process vaccine efficacy working group young woman

项目摘要

DESCRIPTION (provided by applicant): This application is a proposal to serve as the Statistical and Data Management Center of the lnternational Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network, as part of the IMPAACT Leadership Group (LG). The IMPAACT LG is proposing a research agenda for studies in pediatric and maternal populations to address objectives in the following NIAID high priority research areas: Vaccines of high priority to these populations; cure and/or functional cure of HIV; co-infections, co-morbidities and consequences of antiretroviral therapy; prevention of acquisition of HIV; pharmacology, drug formulate and novel interventions. Our Specific Aims are: to support the international research agenda of the IMPAACT LG by providing a group of highly-experienced statisticians, epidemiologists, data managers and other professionals who are committed to collaborating with IMPAACT investigators; to provide expertise and high quality clinical and laboratory data management and communications systems to support the development, conduct and analysis of IMPAACT studies; and to advance the mission of the IMPAACT LG through innovation in study design and analysis, providing leadership in cross-study analyses, developing efficient methods and systems, and promoting harmonization with collaborating networks.

描述（由申请人提供）：本申请是作为Incract Leaderion Group（LG）的一部分，旨在作为LNTernational孕产妇青少年艾滋病临床试验（IncraCT）网络的统计和数据管理中心。 Indaact LG提出了针对儿科和母体人群研究的研究议程，以解决以下NIAID高优先级研究领域的目标：这些人群优先级的疫苗；治愈和/或艾滋病毒的功能治愈；抗逆转录病毒疗法的共同感染，合并症和后果；预防收购艾滋病毒；药理学，药物配方和新干预措施。我们的具体目的是：通过为一组致力于与Incract Regivents合作的专业人士提供一组不可经验的LG的国际研究议程；提供专业知识和高质量的临床和实验室数据管理和通信系统，以支持不良研究的发展，进行和分析；并通过研究设计和分析中的创新来推进LG的使命，从而在跨研究分析中提供领导力，开发有效的方法和系统，并促进与协作网络的协调。