BMI Bioinformatics Training Grant
BMI 生物信息学培训补助金
基本信息
- 批准号:9288162
- 负责人:
- 金额:$ 35.4万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2003
- 资助国家:美国
- 起止时间:2003-07-01 至 2018-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (provided by applicant): Graduate Group in Bioinformatics seeks a second renewal of its training program in Bioinformatics and Computational Biology. The program focuses on training young scientists who can serve as leaders in research at the interface between computation and biology. Emphasis areas include these fields as well as Complex Biological Systems and Quantitative Genetics and Genomics. The training plan for coursework, enrichment activities, and research reflects the fundamentally collaborative culture at UCSF. Thus, both the formal and informal features of the program have been designed to bring together students from different disciplines and train them for team-based problem solving. Although the focus is on computational research, all students must perform an experimental rotation and are heavily exposed to experimental biology in many other aspects of their training. As a result, our graduates understand the sources of their experimental data as well as how to manipulate it and are prepared to interact in multidisciplinary teams that require an understanding of both "wet" and "dry" scientific cultures. We recruit a diverse and talented group of students with computational and quantitative backgrounds and train them to tackle challenging problems in biology at scales that span the molecular to the phenotypic. Because UCSF is a health sciences campuses, many of our students do research explicitly associated with human health and disease. The special features of our program are:
Collaborative and inter-disciplinary research. Training faculty are heavily involved in collaborative research, both within and outside of UCSF. Many of their labs (and trainees) are involved in Consortia or Centers created to address problems that cannot be solved from a single viewpoint but require contributions from many disciplines. Student publications reflect this
culture as do student initiated journal clubs and interest groups bringing together students from multiple disciplines for "Research in Progress" talks.
An innovative curriculum and special training features. Our core values of collaboration and inter- disciplinary research involve first-year students in team-based and hands-on learning. These special features of First Year training begins with a "Bootcamp" experience taught by senior students and then proceeds to a major integrative biological "Systems" course in the fall quarter featuring student teams chosen to span their different backgrounds. A Core curriculum follows in the winter to teach relevant fundamentals. The spring quarter has been refactored to provide a menu of in-depth "mini-courses" held in a small group format for substantive interactions with faculty with deep research involvement in each area.
Significant training in communication and preparation for diverse careers. Students get intensive training in oral and written communication taught in formal courses designed in part by professional staff. Many other venues teach these skills more informally. Students also are given many opportunities to participate in internships, career preparation workshops, and medical education.
描述(由申请人提供):生物信息学研究生小组寻求第二次更新其生物信息学和计算生物学培训计划。该计划的重点是培训年轻科学家,让他们成为计算和生物学之间研究领域的领导者。重点领域包括这些领域以及复杂生物系统和定量遗传学和基因组学。课程作业、丰富活动和研究的培训计划反映了加州大学旧金山分校从根本上讲的协作文化。因此,该计划的正式和非正式特征旨在将来自不同学科的学生聚集在一起,并训练他们以团队为基础解决问题。尽管重点是计算研究,但所有学生都必须进行实验轮换,并在训练的许多其他方面大量接触实验生物学。因此,我们的毕业生了解实验数据的来源以及如何操纵它,并准备在需要了解“湿”和“干”科学文化的多学科团队中进行互动。我们招募了一群具有计算和定量背景的多元化、才华横溢的学生,并训练他们解决从分子到表型的生物学中具有挑战性的问题。由于加州大学旧金山分校是一所健康科学校园,我们的许多学生都从事与人类健康和疾病明确相关的研究。我们计划的特色是:
合作和跨学科研究。培训教师积极参与加州大学旧金山分校内外的合作研究。他们的许多实验室(和学员)都参与了联盟或中心,这些联盟或中心的创建是为了解决从单一观点无法解决但需要多个学科贡献的问题。学生出版物反映了这一点
学生发起的期刊俱乐部和兴趣小组将来自多个学科的学生聚集在一起进行“正在进行的研究”讲座。
具有创新的课程设置和特色培训特色。我们的协作和跨学科研究的核心价值观让一年级学生参与基于团队的实践学习。第一年培训的这些特点从高年级学生教授的“训练营”体验开始,然后在秋季季度进行主要的综合生物“系统”课程,由选择跨越不同背景的学生团队组成。冬季将开设核心课程,教授相关基础知识。春季学期经过重新设计,提供了一系列以小组形式举办的深入“迷你课程”,以便与在每个领域都有深入研究的教师进行实质性互动。
重要的沟通培训和为不同职业做好准备。学生在部分由专业人员设计的正式课程中接受口头和书面交流的强化培训。许多其他场所以更非正式的方式教授这些技能。学生还有很多机会参加实习、职业准备研讨会和医学教育。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Ryan D. Hernandez其他文献
Genomic characterization of serial-passaged Ebola virus in a boa constrictor cell line
蟒蛇细胞系中连续传代埃博拉病毒的基因组特征
- DOI:
10.1101/091603 - 发表时间:
2016 - 期刊:
- 影响因子:0
- 作者:
Greg Fedewa;S. Radoshitzky;Xiaoli Chi;L. Dongb;M. Spear;N. Strauli;M. Stenglein;Ryan D. Hernandez;P. Jahrling;J. Kuhn;J. Derisi - 通讯作者:
J. Derisi
Cutibacterium acnes antibiotic production shapes niche competition in the human skin microbiome
痤疮皮肤杆菌抗生素生产塑造了人类皮肤微生物组的利基竞争
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
Jan Claesen;Jennifer Spagnolo;Stephany Flores Ramos;Kenji L. Kurita;Allyson L. Byrd;A. Aksenov;A. Melnik;W. R. Wong;Shuo Wang;Ryan D. Hernandez;M. Donia;P. Dorrestein;H. Kong;J. Segre;Roger G. Linington;M. Fischbach;K. P. Lemon - 通讯作者:
K. P. Lemon
Evolutionary acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.
从多态性和分歧模式推断出对人类候选顺式调控区域的进化作用。
- DOI:
- 发表时间:
2009 - 期刊:
- 影响因子:0
- 作者:
D. Torgerson;A. Boyko;Ryan D. Hernandez;Amit R. Indap;Xiao;J. Thomas;White;J. Sninsky;M. Cargill;M. D. Adams;C. Bustamante;A. Clark - 通讯作者:
A. Clark
De novo mutations across 1,465 diverse genomes reveal novel mutational insights and reductions in the Amish founder population
1,465 个不同基因组的从头突变揭示了新的突变见解和阿米什创始人群体的减少
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
M. D. Kessler;Douglas P. Loesch;J. Perry;N. Heard;B. Cade;Heming Wang;M. Daya;J. Ziniti;S. Datta;J. Celedón;M. Soto;L. Avila;S. Weiss;K. Barnes;S. Redline;R. Vasan;Andrew D. Johnson;R. Mathias;Ryan D. Hernandez;James G. Wilson;D. Nickerson;G. Abecasis;S. Browning;S. Zoellner;J. O’Connell;B. Mitchell;T. O’Connor - 通讯作者:
T. O’Connor
Title : Dumpster diving in RNA-sequencing to find the source of every last read Authors :
标题:深入研究 RNA 测序,寻找每一次最后阅读的来源 作者:
- DOI:
- 发表时间:
2016 - 期刊:
- 影响因子:0
- 作者:
S. Mangul;H. Yang;N. Strauli;F. Gruhl;Timothy Daley;S. Christenson;Agata Wesolowska;Roberto Spreafico;C. Rios;Celeste Eng;Andrew D. Smith;Ryan D. Hernandez;Roel A. Ophoff;J. R. Santana;Prescott G. Woodruff;E. Burchard;M. Seibold;S. Shifman;E. Eskin;N. Zaitlen - 通讯作者:
N. Zaitlen
Ryan D. Hernandez的其他文献
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{{ truncateString('Ryan D. Hernandez', 18)}}的其他基金
Post Baccalaureate Research Opportunity To Promote Equity In Learning (PROPEL).
促进学习公平的学士学位后研究机会 (PROPEL)。
- 批准号:
10569475 - 财政年份:2022
- 资助金额:
$ 35.4万 - 项目类别:
Post Baccalaureate Research Opportunity To Promote Equity In Learning (PROPEL).
促进学习公平的学士学位后研究机会 (PROPEL)。
- 批准号:
10706542 - 财政年份:2022
- 资助金额:
$ 35.4万 - 项目类别:
Rarely Common: Uncovering the dominant role of rare variants in the genetic architecture of complex human traits.
罕见:揭示罕见变异在复杂人类特征的遗传结构中的主导作用。
- 批准号:
10531261 - 财政年份:2021
- 资助金额:
$ 35.4万 - 项目类别:
Rarely Common: Uncovering the dominant role of rare variants in the genetic architecture of complex human traits.
罕见:揭示罕见变异在复杂人类特征的遗传结构中的主导作用。
- 批准号:
10366074 - 财政年份:2021
- 资助金额:
$ 35.4万 - 项目类别:
Rarely Common: Uncovering the dominant role of rare variants in the genetic architecture of complex human traits.
罕见:揭示罕见变异在复杂人类特征的遗传结构中的主导作用。
- 批准号:
10219000 - 财政年份:2021
- 资助金额:
$ 35.4万 - 项目类别:
Maximizing Opportunities for Research Excellence
最大限度地提高卓越研究的机会
- 批准号:
8996171 - 财政年份:1998
- 资助金额:
$ 35.4万 - 项目类别:
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