Developmental Pathways of Substance Use among Sexual Minority Women

性少数女性物质使用的发展途径

• 批准号: 9129447
• 负责人: Connor J McCabe
• 金额: $ 3.97万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-16 至 2018-08-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9129447
• 关键词: Accounting; Address; Adolescence; Adolescent; Affect; Age; Alcohol abuse; Alcohol or Other Drugs use; Bisexual; Buffers; Childhood; Data; Data Analyses; Data Set; Development; Disease; Drug abuse; Drug usage; Early identification; Elderly; Environmental Risk Factor; Epidemiologic Studies; Equation; Factor Analysis; Goals; Growth; Heterosexuals; Individual; Intervention; Lesbian; Lesbian Gay Bisexual; Life; Longevity; Measures; Mediating; Mediation; Mediator of activation protein; Mental Health; Minority; Modeling; National Institute of Drug Abuse; Parents; Pathway interactions; Population; Populations at Risk; Prevalence; Prevention program; Preventive Intervention; Preventive treatment; Process; Prospective Studies; Psyche structure; Public Health; Reporting; Research; Risk; Risk Factors; Sampling; Sex Orientation; Sexual abuse; Social support; Source; Stress; Substance Use Disorder; Targeted Research; Testing; Time; United States; Woman; Women Status; Youth; age related; coping; deter alcohol use; early childhood; emotion dysregulation; experience; girls; health disparity; inner city; innovation; intervention program; member; peer; physical abuse; physical assault; prospective; psychologic; public health relevance; resilience; response; sexual minority; stressor; theories; young adult

 DESCRIPTION (provided by applicant): Alcohol and drug abuse among sexual minority women (SMW) is an increasingly recognized public health concern in the United States. Across a multitude of nationally-representative samples, SMW populations report higher rates of substance use and disorder (SU/D) across the lifespan, and further report greater levels of adversity in both childhood and adolescence as members of a stigmatized group.1,2 Although minority stress models suggest that higher levels of adversity may explain mental health disparity among sexual minority populations,3,4 few studies have examined the impact of adversity across development among SMW in predicting SU/D in later life; none have examined psychological mediators of this proposed pathway; and none have examined moderators of this developmental pathway. The goal of the present proposal is to examine the impact of adversity on psychological risk factors of SU/D across development and address protective factors that reduce risk for later SU/D among SMW. Specifically, the proposed study will test whether adversity and subsequent increases in emotion dysregulation (ED) among SMW in childhood and adolescence account for higher levels of SU/D through young adulthood, and will examine whether social support from peers and parents within adolescence buffers this proposed risk pathway. Data will be drawn from 2,278 heterosexual and 173 sexual minority women who participated in the Pittsburgh Girls Study. The Pittsburgh Girls Study is a large, diverse sample of inner-city girls followed prospectively from age 5 to age 23, and contains a large longitudinal sample of SMW ideal for addressing the proposed study aims. Factor analysis, latent growth curve modeling (LGM), and multi-group structural equation modeling (SEM) will be used to test 1) whether ED and adversity experiences in childhood and adolescence predict increases and higher levels of SU/D through young adulthood; 2) whether ED mediates the effects of adversity and SMW status on SU/D, and whether ED moderates the impact of adolescent adversity on SU/D; and 3) whether social support moderates the effect of ED and early and adolescent adversity on later SU/D across sexual orientation groups. Addressing these questions will inform both preventative and treatment intervention efforts to reduce the prevalence of substance disorder among lesbian, gay, and bisexual populations by informing the early identification of environmental risk factors associated with sexual minority status across development; by identifying target psychological processes that have a direct impact on substance use and disorder among lesbian, gay, and bisexual individuals; and by addressing risk and resilience in the context of social support within this at-risk population.

 描述（由适用提供）：在美国，性少数妇女（SMW）中的酒精和药物滥用是美国越来越认可的公共卫生问题。在众多全国代表性的样本中，SMW人群报告了整个寿命的物质使用和混乱率（SU/D）的率更高，并进一步报告了在儿童期和青少年中，作为污名化组的成员的广告水平更高。11,2。少数派压力模型中的较高的广告能够在预测广告中的较高水平，这表明了较高的广告范围的发展，而少数少数研究的少数研究却少于3,4，4，少数的研究，而是3 3,4,4,4,4,4,4后来的苏/D；没有人检查过这一拟议途径的心理媒介。没有人检查过这种发展途径的主持人。本提案的目的是检查广告对跨开发的心理风险因素的影响，并解决受保护因素，以降低SMW中以后SU/D的风险。具体而言，拟议的研究将测试童年时期和青少年在SMW中的广告和随后的情绪失调（ED）是否会占更高水平的SU/D到年轻人，并将检查青少年缓冲区中同伴和父母的社会支持是否这一拟议的风险途径。数据将来自2,278个异性恋和173名参加匹兹堡女孩研究的性少数妇女。匹兹堡女孩的研究是一个大型的潜水城市中心女孩样本，从5岁到23岁，并包含大量的SMW纵向样本，非常适合解决拟议的研究目的。因子分析，潜在生长曲线建模（LGM）和多组结构对等模型（SEM）将用于测试1）ED和青少年的ED和广告经验是否可以预测到年轻成年期的SU/D的增加和更高水平； 2）ED是否介导了广告和SMW状态对SU/D的影响，以及ED是否适应了青少年广告对SU/D的影响； 3）社会支持是否会节省ED和早期和青少年广告对跨性取向群体的后期SU/D的影响。解决这些问题将为预防性和治疗干预措施提供介绍，以减少女同性恋，同性恋和双性恋人群中物质障碍的普遍性，通过告知对整个发展中与性少数族裔状况相关的环境风险因素的早期识别；通过确定对女同性恋，同性恋和双性恋个人中对药物使用和混乱有直接影响的目标心理过程；通过在这种高危人群中的社会支持背景下解决风险和韧性。