2017 Cell Biology of Metals Gordon Research Conference and Gordon Research Seminar

2017金属细胞生物学戈登研究会议暨戈登研究研讨会

• 批准号: 9328227
• 负责人: MICHAEL J. PETRIS
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-22 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9328227
• 关键词: Academia; Applied Research; Area; Bacteria; Basic Science; Biochemistry; Biogenesis; Biological Models; Biology; Cells; Cellular biology; Chemistry; Collaborations; Columbidae; Communicable Diseases; Development; Discipline; Disease; Environment; Enzymes; Evaluation; Fertilization; Fostering; Future; Genetic; Goals; Government Agencies; Health; Homeostasis; Human; Industry; Institution; International; Ions; Knowledge; Lead; Link; Medicine; Metabolic Diseases; Metalloproteins; Metals; Methodology; Microbe; Molecular; Nature; Oral; Organelles; Participant; Physiology; Play; Proteins; Regulation; Research; Research Personnel; Role; Scientist; Series; Signal Transduction; Snow; Structural Biologist; System; Therapeutic; Time; Vermont; Whole Organism; Work; absorption; career; cofactor; graduate student; high standard; human disease; improved; innovation; interest; lectures; meetings; metal metabolism; metalloenzyme; novel diagnostics; novel strategies; pathogen; peer; posters; prognostic; programs; structural biology; symposium; unpublished works

Project Description (Summary/Abstract) The Gordon Research Conference (GRC) series on the “The Cell Biology of Metals” provides a truly outstanding forum for scientific exchanges, presentations and discussions in the emerging field of metals in biology, focusing on the acquisition, distribution, sensing and utilization of metals in proteins, cells and systems from bacteria to humans. This GRC series was initiated in 2005 and in the next cycle was immediately oversubscribed, illustrating that the meeting filled an important niche exploring the molecular mechanisms of metal utilization in proteins, organelles, and whole organisms. This conference has now become a cornerstone of the field and is unique in attacking broad research questions such as how metal cofactors are assembled to how metal ions play roles in metabolic and infectious diseases. The Cell Biology of Metals GRC is held every two years and has consistently attracted more than 140 attendees. The Gordon Research Conference series is internationally renowned for the high-quality, cutting edge nature of its meetings, showcasing unpublished work; the program of the proposed 2017 conference strives to maintain this high standard. The 2017 Cell Biology of Metals GRC will be held on July 23 – 28 at Mount Snow in West Dover, VT. This application describes the preliminary program, which is organized around the theme of “Mechanisms from Microbes to Humans”. Session topics include metals in enzyme function, metalloenzyme strucutres, metal homeostasis, metal sensing and dynamics, metalloprotein biogenesis and signaling, metals in host-pathogen interactions and metals in physiology and disease. The conference will be comprised of keynote presentations, research and poster talks, poster discussions, and informal scientific discussions. This meeting will bring together an outstanding and diverse cadre of molecular and structural biologists, biochemists, geneticists, cell biologists, physiologists and clinicians to interact and brainstorm on new discoveries, ideas and directions in basic and applied research on the cell biology of metals. Given the increase in the number of metabolic and infectious diseases linked to changes in cellular metal homeostasis, this meeting fills a critical niche for investigating the underlying mechanism(s) of these disorders and for brainstorming approaches for novel diagnostics, prognostics, and therapeutics.

项目描述（摘要/摘要） Gordon研究会议（GRC）系列“金属细胞生物学”提供了曲折 杰出的科学交流论坛，在新兴金属领域中的基础和讨论中的杰出论坛 生物学，专注于蛋白质，细胞和系统中金属的获取，分布，传感和利用 从细菌到人类。 过度额定的，说明了会议填补了探索分子机制的厌恶的利基市场 蛋白质，细胞器和整个生物的使用。 该领域的基石和IND攻击诸如金属辅因子的攻击场所 组装金属离子如何在代谢和传染病中发挥作用。 每两年举行一次，并一直吸引了140多名参与者 会议系列以国际著名，以高质量，最前沿的IS会议的性质， 展示未出版的工作； 标准。 2017年金属的细胞生物学GRC将于7月23日至28日在弗吉尼亚州西多佛的Snow举行。 应用描述了初步计划，该程序围绕“机制”组织 人类的微生物”。会话主题包括酶功能中的金属，金属酶纹状体，金属 稳态，金属感测和动力学，金属蛋白生物发生和信号传导，宿主 - 病原体中的金属 生理和疾病中的相互作用和金属将由主题演讲组成 演讲，研究和海报会议，海报讨论和信息讨论。 将汇集一个杰出而多样化的分子和结构生物学家，生物化学家， 遗传学家，细胞生物学家，生理学家和临床医生就新发现，思想和思想进行互动和集思广益 基础和应用金属细胞生物学的方向。 与细胞金属稳态变化有关的代谢和传染病，这次会议充满了关键 研究这些疾病的基本机制以及用于头脑风暴方法的利基市场 新颖的诊断，程序和治疗学。