Primate Diagnostic Services Laboratory

灵长类动物诊断服务实验室

• 批准号: 9207539
• 负责人: Richard Grant
• 金额: $ 44.34万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9207539
• 关键词: Animals; Biological Assay; Breeding; Caring; Certification; Collaborations; Comparative Pathology; Country; Data; Decision Making; Detection; Diagnostic; Diagnostic Services; Diagnostic tests; Ensure; Fees and Charges; Goals; Health; Human; Individual; Infectious Agent; International; Laboratories; Medical Care Team; Methods; Mission; Monitor; Notification; Occupational Health; Periodicity; Play; Preparation; Primates; Procedures; Provider; Readiness; Reagent; Reporting; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Role; Sampling; Serologic tests; Serotyping; Services; Source; Specificity; System; Test Result; Testing; Time; Update; Validation; Variant; Veterinarians; Viral; Viral Antigens; Virus; Washington; Work; Zoonoses; animal care; base; disease transmission; germ free condition; improved; interest; operation; price lists; programs; recombinant peptide; repository

DIVISION OF PRIMATE RESOURCES: PRIMATE DIAGNOSTIC SERVICES LABORATORY PROJECT SUMMARY The Primate Diagnostic Services Laboratory (PDSL) plays an important role in the Center’s breeding, research and occupational health programs through timely testing and notification of veterinarians and colony managers of the virus status of all animals. The goals of this effort are threefold: 1) Periodic monitoring of the virus status of animals to identify and separate infected animals in the interest of improving the overall health of the colony, maintain specific pathogen free (SPF) groups and determine the research-readiness of individual animals for specific studies based on their virus, fungal, and parasitic status; and 2) Decrease the possibility if infected animals interfering with interpretation of study data and decrease potential for viral zoonotic disease transmission to human care providers and investigators; and 3) provide banked and characterized viral stocks, particularly SRV stocks, and concentrated virus antigen preparations of all known SRV serotypes, to be used as assay reagents in the PDSL and made available to other primate diagnostic labs upon request. These goals are achieved by working closely with the Associate Director (AD), Division of Primate Resources Operations (DPRO), Breeding Colony Management Services (BCMS), Veterinary Services (VS), Comparative Pathology Services (CPS), and Primate Service (PS) Units within the WaNPRC as well as maintaining close contacts and collaborations with other NPRC testing laboratories. Colony veterinarians and managers across the country rely on PDSL virus testing results to segregate groups of animals according to their viral status and planned use(s) in research projects.

灵长类动物资源部：灵长类动物诊断服务实验室 项目摘要 灵长类动物诊断服务实验室（PDSL）在中心的繁殖，研究中起着重要作用 以及通过及时测试和通知兽医和殖民地经理的职业健康计划 所有动物的病毒状况。这项工作的目标是三重：1）定期监测病毒状况 为了改善菌落的整体健康，识别和分离感染动物的动物的动物， 维持特定的无病原体（SPF）组，并确定单个动物的研究对 根据其病毒，真菌和寄生状态的具体研究； 2）如果感染了可能性 动物与研究数据的解释相互作用并减少病毒性人畜共患病的潜力 向人类护理提供者和研究人员传播； 3）提供了存储和特征的病毒库存， 特别是使用所有已知SRV血清型的SRV库存和浓缩病毒抗原制剂 作为PDSL中的测定试剂，可应要求提供给其他主要诊断实验室。这些目标 通过与灵长类动物资源运营部副主任（AD）紧密合作来实现 （DPRO），繁殖菌落管理服务（BCMS），兽医服务（VS），比较病理学 WANPRC中的服务（CPS）和灵长类服务（PS）单位，并保持密切联系和 与其他NPRC测试实验室的合作。全国殖民地兽医和经理 依靠PDSL病毒测试结果根据动物的病毒状态分离动物并计划 在研究项目中使用。