Naional Cancer Institute, Naitonal Clinical Trials Network U10 Lead Academic Site

国家癌症研究所、国家临床试验网络 U10 首席学术网站

基本信息

批准号：
9242575
负责人：
STEVEN R ALBERTS
金额：
$ 136.79万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-05-06 至 2019-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9242575
关键词：
Address American College of Radiology Imaging Network American College of Surgeons Oncology Group Cancer and Leukemia Group B Clinic Clinic Activity Clinical Research Clinical Trials Clinical Trials Network Collection Data Eastern Cooperative Oncology Group Goals Grant Gynecologic Oncology Group Image Institutes Institution Journals Lead Leadership Malignant Neoplasms Mayo Clinic Cancer Center North Central Cancer Treatment Group Patients Publishing Radiation Therapy Oncology Group Reporting Research Research Infrastructure Research Personnel Role Site Structure Support System United States National Institutes of Health Work base burden of illness member public health relevance

Address American College of Radiology Imaging Network American College of Surgeons Oncology Group Cancer and Leukemia Group B Clinic Clinic Activity Clinical Research Clinical Trials Clinical Trials Network Collection Data Eastern Cooperative Oncology Group Goals Grant Gynecologic Oncology Group Image Institutes Institution Journals Lead Leadership Malignant Neoplasms Mayo Clinic Cancer Center North Central Cancer Treatment Group Patients Publishing Radiation Therapy Oncology Group Reporting Research Research Infrastructure Research Personnel Role Site Structure Support System United States National Institutes of Health Work base burden of illness member public health relevance

展开

项目摘要

DESCRIPTION (provided by applicant): Mayo Clinic has had a long-standing commitment to support and lead NCTN clinical trials through NCCTG, ECOG, ACOSOG, ACRIN, RTOG, and GOG. Mayo Clinic served as the founding institution and operational base for NCCTG until its merger with CALGB and ACOSOG to form the Alliance. Mayo investigators have also had leadership roles in these groups as well as in the newly forming groups (Alliance, ECOG-ACRIN, and NRG). The current clinical research structure within the Mayo Clinic Cancer Center (MCCC) continues to prioritize NIH sponsored trial, including NCTN trials, over other trials. Support systems are in place within the MCCC to maximize accrual and to support the translational components of these trials, including biospecimen collection and imaging. Mayo investigators also remained very active in trial leadership. Mayo investigators have also been very effective in utilizing data and biospecimens collected from NCTN trials to address important and relevant research questions. Through this commitment to research, Mayo investigators have published multiple reports in high impact journals and successfully obtained multiple grants, including R01 grants, to support this work.

描述（由申请人提供）：Mayo Clinic长期以来一直致力于通过NCCTG，ECOG，ACOSOG，ACRIN，RTOG和GOG来支持和领导NCTN临床试验。梅奥诊所（Mayo Clinic）担任NCCTG的创始机构和运营基地，直到与Calgb和Acosog合并以组成联盟为止。梅奥的调查人员还在这些小组以及新成立的小组（联盟，ecog-acrin和NRG）中发挥了领导作用。 Mayo临床癌症中心（MCCC）内的当前临床研究结构继续优先考虑NIH赞助的试验，包括NCTN试验，而不是其他试验。支持系统在MCCC内建立，以最大程度地提高应计并支持这些试验的翻译组成部分，包括生物测量收集和成像。梅奥的调查人员在审判领导中也仍然非常活跃。 Mayo研究人员在利用NCTN试验中收集的数据和生物测量方面也非常有效，以解决重要和相关的研究问题。通过对研究的承诺，梅奥研究人员在高影响期刊上发表了多个报告，并成功获得了包括R01赠款在内的多项赠款，以支持这项工作。