Administrative Core

行政核心

• 批准号: 9332145
• 负责人: DENNIS J. HARTIGAN-O'CONNOR
• 金额: $ 10.22万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-19 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9332145
• 关键词: Address; Administrator; California; Collaborations; Communication; Data; Decision Making; Disputes; Elements; Ensure; Environment; Fostering; Future; Geography; Goals; HIV; Human; Immunity; Individual; International; Kinetics; Medicine; National Institute of Allergy and Infectious Disease; Online Systems; Peer Review; Primates; Process; Program Research Project Grants; Publications; Reporting; Research; Research Personnel; Resolution; Resource Sharing; Resources; Role; Sampling; Scientist; Specialist; Structure; T-Lymphocyte; Therapeutic; United States National Institutes of Health; Work; base; cohort; comparative; data sharing; experience; innovation; multidisciplinary; nonhuman primate; organizational structure; programs; synergism; vaccine trial

This Research Program Project, titled Role of reservoir composition and T cell immunity in HIV rebound kinetics (RETIRE-HIV), will use samples from ongoing human therapeutic vaccination trials and synergistic non-human primate studies to ask how host immunity can alter rebound kinetics. The Program has a strong multidisciplinary and international character, established by a team of expert PIs who are longstanding collaborators and have access to unique cohorts of rebounding individuals. Such diversity, including geographic diversity, requires a strong administrative structure to promote synergy between the programmatic elements by facilitating regular, structured communication. This Administrative Core will provide overall organizational structure for the Program Project, perform administrative functions, interface with NIH/NIAID staff, foster cooperation between projects and cores, encourage criticism and advice from its scientists, promote fiscal responsibility, and assure the continued excellence of the Project and its ability to address the Specific Aims. The Administrative Core will be based at UC Davis and directed by the Program Project's co-overall PIs, Drs. Hartigan-O'Connor and Barry. These investigators have long worked together as Core Scientists at the California National Primate Research Center (CNPRC). Dr. Barry was Director of the CNPRC from 2014-2015 and is now Director of the adjacent Center for Comparative Medicine. Thus, he has abundant experience in management of large collaborative projects such as this. The Core's organization is supplemented by administrators, specialists, the External Scientific Advisory Board, and an Internal Steering Committee. The specific aims of the Administrative Core are: 1. Provide an organizational and programmatic structure to promote scientific excellence. 2. Provide organizational and financial oversight and future planning, establish decision-making processes, set priorities, and resolve disputes 3. Ensure efficient data, information, and resource sharing.

这个研究计划项目，标题为储层组成和T细胞免疫在HIV中的作用 反弹动力学（退休HIV）将使用正在进行的人类治疗疫苗接种试验中的样品 和协同的非人类灵长类动物研究询问宿主免疫如何改变反弹动力学。这 计划具有强大的多学科和国际特征，由专家PI团队建立 长期的合作者，并可以访问独特的篮板个人。如此多样性， 包括地理多样性在内，需要强大的行政结构来促进 通过促进常规结构化沟通来进行程序化元素。这个行政核心将提供 计划项目的总体组织结构，执行管理功能，与 NIH/NIAID员工，促进项目与核心之间的合作，鼓励其批评和建议 科学家，促进财政责任，并确保项目的持续卓越及其能力 解决具体目标。 行政核心将设在加州大学戴维斯分校，并由该计划项目的共同抛弃PIS指导。 Hartigan-O'Connor和Barry。这些调查人员长期以来一直担任核心科学家 加利福尼亚国家灵长类动物研究中心（CNPRC）。 Barry博士于2014- 2015年担任CNPRC的主任 现在是邻近比较医学中心的主任。因此，他有丰富的经验 这样的大型协作项目的管理。核心的组织补充了 管理员，专家，外部科学顾问委员会和内部指导委员会。 行政核心的具体目的是： 1。提供组织和程序性结构，以促进卓越的科学卓越。 2.提供组织和财务监督以及未来计划，建立决策过程，设定 优先事项并解决争议 3.确保有效的数据，信息和资源共享。