Administrative Core

行政核心

• 批准号: 8643811
• 负责人: Yoel Sadovsky
• 金额: $ 2.29万
• 依托单位: MAGEE-WOMEN'S RES INST AND FOUNDATION
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8643811
• 关键词: Address; Advisory Committees; Animal Model; Collaborations; Communication; Communities; Conflict of Interest; Data Collection; Ensure; Environment; Epigenetic Process; Genetic; Goals; Institutional Review Boards; Laboratories; Leadership; Maintenance; Metabolic; Metabolism; Molecular; Policies; Principal Investigator; Program Research Project Grants; Progress Reports; Protocols documentation; Publications; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resource Sharing; Resources; Safety; United States National Institutes of Health; Universities; data modeling; data sharing; meetings; programs; success; tool; web site

Program Director/Principal Investigator (Last, First, Middle): SADOVSKY, YOEL B. Core A: Summary The goal of the proposed program project is to examine genetic, epigenetic, and cellular controls of placental metabolism and function, focusing on placental storage and metabolism of metabolic fuels. Within this context, this core will serve as the central leadership and oversight office for the administration and coordination of all activities associated with the proposed project program grant. The primary functions of the Administrative Core will be to 1) facilitate interaction and communication among affiliated research groups, and with the external advisory committee 2) coordinate infrastructure and shared resources that support all three research projects and 3) ensure that all administrative, reports, safety and compliance needs are met expeditiously and efficiently. The small yet vital administrative core will serve this goal by general planning, coordination, initiation, and management of all programmatic aspects. As synergy among the three research groups is central to the programmatic success of the project, the core will assure the efficient communication and collaboration among the three projects. This will also include the conduct of regular PI meetings as well as shared laboratory meetings at monthly intervals. Using economies-of-scale principles, the administrative core will oversee the efficient use of purchasing and use of external resources at the University of Pittsburgh and other entities. The core will assure the submission and maintenance of lACUC, IRB protocols, and other safety-related protocols, track publications, and provide progress reports and other administrative reviews to the NIH, as required. The core will convene and coordinate the interaction with program's external advisory committee. Finally, the core's PI will serve to resolve any conflicts of interests that might arise during the course of the program. The core will provide data collection and sharing tools for the research groups and cores through creation and maintenance of an internal web site, coordinated with the MWRI IT staff. The administrative core will also facilitate investigator interactions with the appropriate offices within MWRI and the University of Pittsburgh to provide appropriate external sharing of data and model organisms, in compliance with NIH policies.

计划总监/首席调查员（最后，第一，中间）：萨德夫斯基，Yoel B.核心A：摘要 提议的计划项目的目的是检查胎盘的遗传，表观遗传和细胞控制 代谢和功能，重点是胎盘储存和代谢燃料的代谢。在这种情况下， 该核心将担任所有人管理和协调的中央领导和监督办公室 与拟议项目计划赠款相关的活动。管理核心的主要功能 将是1）促进附属研究小组之间的互动和沟通，与外部 咨询委员会2）协调基础架构和共享资源，以支持所有三个研究项目 3）确保迅速满足所有行政，报告，安全和合规需求 有效。 小而重要的行政核心将通过一般规划，协调，启动和 所有程序化方面的管理。由于三个研究小组之间的协同作用是 该项目的编程成功，核心将确保有效的沟通和协作 这三个项目。这还将包括定期的PI会议以及共享实验室的举措 每月一次会议。使用规模经济原则，行政核心将监督 在匹兹堡大学和其他实体上有效利用购买和使用外部资源。这 核心将确保提交和维护LACUC，IRB协议和其他与安全有关的协议， 跟踪出版物，并根据需要向NIH提供进度报告和其他行政审查。这 核心将与计划的外部咨询委员会召集并协调互动。最后，核心的 PI将有助于解决计划过程中可能出现的任何利益冲突。 核心将通过创建为研究小组和核心提供数据收集和共享工具 维护内部网站，与MWRI IT人员协调。行政核心也将 促进调查员与MWRI和匹兹堡大学的适当办事处的互动 根据NIH政策，提供适当的数据和模型生物的外部共享。