2014 Biology of Host-Parasite Interactions Gordon Research Conference

2014年宿主-寄生虫相互作用生物学戈登研究会议

• 批准号: 8716948
• 负责人: STEPHEN L HAJDUK
• 金额: $ 0.6万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-15 至 2014-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8716948
• 关键词: Acquired Immunodeficiency Syndrome; Address; African Trypanosomiasis; Amebic colitis; Area; Biology; Centers for Disease Control and Prevention (U.S.); Chagas Disease; Collaborations; Collection; Communicable Diseases; Communities; Cryptosporidiosis; Development; Disease; Faculty; Fostering; Future; Gender; Health; Helminths; Human; Infection; Learning; Leishmaniasis; Malaria; National Institute of Allergy and Infectious Disease; Opportunistic Infections; Parasites; Parasitic Diseases; Parasitology; Pathogenesis; Pharmaceutical Preparations; Positioning Attribute; Published Comment; Reproduction spores; Research; Research Personnel; Scientist; Secure; Staging; Students; Toxoplasma; Toxoplasmosis; Training; Transplant Recipients; Trichomonas; Tropical Disease; Vaccines; Virulence Factors; Work; base; biodefense; career; congenital infection; meetings; member; neglect; parasitism; pathogen; programs; public health relevance; symposium; Acquired Immunodeficiency Syndrome; Address; African Trypanosomiasis; Amebic colitis; Area; Biology; Centers for Disease Control and Prevention (U.S.); Chagas Disease; Collaborations; Collection; Communicable Diseases; Communities; Cryptosporidiosis; Development; Disease; Faculty; Fostering; Future; Gender; Health; Helminths; Human; Infection; Learning; Leishmaniasis; Malaria; National Institute of Allergy and Infectious Disease; Opportunistic Infections; Parasites; Parasitic Diseases; Parasitology; Pathogenesis; Pharmaceutical Preparations; Positioning Attribute; Published Comment; Reproduction spores; Research; Research Personnel; Scientist; Secure; Staging; Students; Toxoplasma; Toxoplasmosis; Training; Transplant Recipients; Trichomonas; Tropical Disease; Vaccines; Virulence Factors; Work; base; biodefense; career; congenital infection; meetings; member; neglect; parasitism; pathogen; programs; public health relevance; symposium

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) Host-parasite Interactions is the most prominent venue for scientific exchange at the leading edge of modern parasite research. This conference has been consistently at the forefront of the field since its inception in 1981 (originally under the title Parasitism). The conference will focus on new concepts and approaches in the study of parasites and their interaction with humans. This meeting will specifically address mechanisms of pathogenesis both from the viewpoint of parasite virulence factors and also changes in the host associated with infection. This group includes a large number of important disease causing agents with national and global impact. Among these are classical agents of tropical disease including malaria, sleeping sickness, chagas disease, leishmaniasis and amebic dysentery and numerous helminth infections. Together they claim millions of lives around the world. Parasitic disease are also highly prevalent in the U.S. including toxoplasmosis, cryptosporidiosis and trichomiasis. Trichomonas alone causes more than 7 million symptomatic infections each year in the U.S. Toxoplasma causes congenital infection. Some of these diseases are of a particular importance as opportunistic infections in AIDS and transplant patients and a number of parasites (in particular those with spore-like infectious stages) are of biodefense concern and are featured on Appendix B of the CDC/NIAID pathogen list. Numerous important challenges remain largely unmet when facing these diseases. There is currently no effective vaccine available for any human parasite and the options for drug treatment are far from satisfactory. The GRC is highly valued by the community as an opportunity to gain an overview of the entire field, to learn about the most recent and most exciting advances and to discuss and set the national and global research agenda for the future. It is also an important opportunity for trainees to foster their professiona development.

描述（由申请人提供）：戈登研究会议（GRC）寄宿寄生虫相互作用是现代寄生虫研究领先优势的科学交流场所。自1981年成立以来，这次会议一直一直处于该领域的最前沿（最初是寄生虫的标题）。该会议将重点介绍寄生虫研究的新概念和方法及其与人类的互动。这次会议将从寄生虫毒力因子的角度以及与感染相关的宿主的变化中特别解决发病机理的机制。该小组包括大量重要疾病，导致具有国家和全球影响的药物。其中包括热带疾病的经典药物，包括疟疾，睡眠疾病，查加斯疾病，利什曼病和阿米比克痢疾以及许多蠕虫感染。他们共同夺走了世界各地数百万的生命。在美国，寄生疾病也很普遍，包括弓形虫病，隐孢子虫病和三核病病。在美国，仅毛果纳斯就会每年引起超过700万个症状感染，从而引起先天性感染。这些疾病中的某些疾病非常重要，因为艾滋病和移植患者的机会性感染，以及许多寄生虫（尤其是那些具有孢子状感染性阶段的寄生虫）引起了生物浮雕的关注，并且在CDC/NIAID病原体列表的附录B上列出了。在面对这些疾病时，许多重要的挑战在很大程度上没有得到满足。目前尚无任何人类寄生虫的有效疫苗，药物治疗的选择远非令人满意。 GRC受到社区的高度重视，这是一个概述整个领域的机会，了解最新和最令人兴奋的进步，并讨论并为未来的国家和全球研究议程进行讨论和设定。对于学员来说，这也是促进其职业发展的重要机会。